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VBI researchers establish new tree of life for gamma-proteobacteria

A new "tree of life" has been constructed by researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech for the gamma-proteobacteria, a large group of medically and scientifically important bacteria that includes Escherichia coli, Salmonella typhimurium, and other disease-causing organisms.

18 May 2010

Population Diagnostics receives NINDS grant for identifying genetic causes of Parkinson's Disease

Population Diagnostics, Inc. ("PDx"), a private company with a novel approach to revealing the genetic causes of disease and predicting drug response, announced today it has been awarded a federal grant to identify the genetic causes of Parkinson's Disease. Funded by the National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health, the project is being led by Eli Hatchwell, MD, PhD, an Associate Professor at Stony Brook University Medical Center and a co-founder of PDx.

18 May 2010

152 research and training grants awarded to researchers at 93 institutions nationwide

The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has awarded 152 new national research and training grants totaling $50,717,000 in the first of two grants cycles for 2010. The grants, primarily to early career researchers, cover a broad range of investigator-initiated ideas at 93 institutions nationwide, from whether cadmium exposure increases the risk of endometrial cancer, to studies of plant and bacterial-bourne compounds, to a study on a protein called survivin that could lead to novel drugs targeting prostate cancer.

18 May 2010

WaferGen Biosystems first-quarter revenues increase to $389,785

WaferGen Biosystems, Inc., a leading developer of state-of-the-art genome analysis systems, today reported performance results for the first quarter ended March 31, 2010.

17 May 2010

Blood-flow fMRI to be used to study brain-wide impact of neural circuitry changes

Like a motorist who knows that the "check engine" light indicates something important but ill-defined is happening, neuroscientists have relied heavily on an incompletely understood technology called functional magnetic resonance imaging to show them what the brain is doing when people respond to different stimuli.

17 May 2010

UNC-developed technique has broad applications in cancer, biomedical research

A precise understanding of cellular growth and movement is the key to developing new treatments for cancer and other disorders caused by dysfunctional cell behavior. Recent breakthroughs in genetic medicine have uncovered how genes control whether cellular proteins are turned 'on' or 'off' at the molecular level, but much remains to be understood about how protein signaling influences cell behavior.

17 May 2010

Genes living in the outskirts of chromosomes more prone to duplication: Study

The ability of yeast cells to convert sugar to alcohol, the key process in the production of beer and wine, can be attributed to a remarkable evolutionary process. The genes that allow yeast to digest sugars in fruits and grains have been duplicated several times over the course of time - allowing for optimal conversion of different types of sugars (such as sucrose and maltose) into alcohol.

17 May 2010

Research sheds light on early embryogenesis, genetic disease

Chromosome 22q11 deletion syndrome (also known as DiGeorge syndrome) is the most common human chromosome deletion syndrome, having an estimated incidence of at least one in 4,000 live births.

15 May 2010

HSPH researchers succeed in locking malaria parasites within infected blood cells

Harvard School of Public Health researchers and colleagues seeking to block invasion of healthy red blood cells by malaria parasites have instead succeeded in locking the parasites within infected blood cells, potentially containing the disease.

15 May 2010

LiU researchers discover new mechanism in stem cell regulation

A hitherto unknown function that regulates how stem cells produce different types of cells in different parts of the nervous system has been discovered by researchers at Linköping University.

15 May 2010

Ecological speciation linked to emergence of new fungal diseases in plants

A new commentary on the nature of pathogens is raising startling new questions about the role that fundamental science research on evolution plays in the understanding of emerging disease.

15 May 2010

Fat tissue different in men and women

The age-old question of why men store fat in their bellies and women store it in their hips may have finally been answered: Genetically speaking, the fat tissue is almost completely different.

15 May 2010

Oxygen levels induce X chromosome inactivation in female cells: Study

Oxygen levels in the lab can permanently alter human embryonic stem (ES) cells, specifically inducing X chromosome inactivation in female cells, according to Whitehead Institute researchers. Human ES cells have been routinely created and maintained at atmospheric levels of oxygen, which is about 20%. Cells in the body are usually exposed to only 1-9% oxygen.

14 May 2010

Measuring gene expression in healthy women may predict future breast cancer risk, say scientists

Researchers at Georgetown Lombard Comprehensive Cancer Center have been able to show, in mice, how just a little adjustment in the expression of two common genes can promote the kind of cellular changes that led to breast cancer. They say these tweaks likely mimic natural variation women have in expression of the two genes.

14 May 2010

Mild-mannered organelles can detect virus invasion signals: Researchers

Within cells, an ancient antiviral duo can deliver a one-two knockout to thwart invading viruses, report researchers who have just unmasked the cellular sidekick that throws the first punch. The findings mean scientists must rethink the design of antiviral immunity and how the body fends off viruses of all types, including influenza and HIV.

14 May 2010

CyGene Laboratories reports heightened interest in at-home genetic testing

CyGene Laboratories Inc. today announced that it has experienced unprecedented levels of interest and requests for information following recent media coverage of Walgreens' decision to offer genetics testing kits supplied by Pathway Genomics in certain of their retail stores.

13 May 2010

Research article focuses on how IECs respond to probiotic strain B. lactis HN019

Probiotics are a group of live microorganisms administered in adequate amounts which confer a beneficial health effect on the host. This bacterial community plays a pivotal role in human nutrition and health by promoting the supply of nutrients, preventing pathogen colonization and shaping and maintaining normal mucosal immunity.

13 May 2010

Researchers to discuss various implications for personalized medicine during one-day symposium

On May 27, researchers with the National Human Genome Research Institute and the National Cancer Institute, along with Group Health Cooperative in Seattle and Henry Ford Health System, will debate and discuss that question during the one-day symposium "Multiplex Initiative: Implications for Personalized Medicine."

13 May 2010

Four caged xanthones can inhibit growth of CCA cell lines: Research article

Cholangiocarcinoma is a malignant tumor, characterized by a poor prognosis and unresponsive to conventional chemotherapeutic agents. Therefore, searching for novel and effective therapeutic agents for CCA is necessary. In previous studies, several caged xanthones from G. hanburyi have been reported to be potent antiproliferatives as well as having anticancer and anti-tumor activities and they induce apoptosis in various cancer cell lines.

13 May 2010

NARSAD honours UNC's Patrick Sullivan with 2010 Distinguished Investigator Award

Patrick Sullivan, MD has received a 2010 Distinguished Investigator Award from NARSAD for a comparison of genetics in schizophrenia and bipolar disorder.

13 May 2010

Genes News and Research

VBI researchers establish new tree of life for gamma-proteobacteria

Population Diagnostics receives NINDS grant for identifying genetic causes of Parkinson's Disease

152 research and training grants awarded to researchers at 93 institutions nationwide

WaferGen Biosystems first-quarter revenues increase to $389,785

Blood-flow fMRI to be used to study brain-wide impact of neural circuitry changes

UNC-developed technique has broad applications in cancer, biomedical research

Genes living in the outskirts of chromosomes more prone to duplication: Study

Research sheds light on early embryogenesis, genetic disease

HSPH researchers succeed in locking malaria parasites within infected blood cells

LiU researchers discover new mechanism in stem cell regulation

Ecological speciation linked to emergence of new fungal diseases in plants

Fat tissue different in men and women

Oxygen levels induce X chromosome inactivation in female cells: Study

Measuring gene expression in healthy women may predict future breast cancer risk, say scientists

Mild-mannered organelles can detect virus invasion signals: Researchers

CyGene Laboratories reports heightened interest in at-home genetic testing

Research article focuses on how IECs respond to probiotic strain B. lactis HN019

Researchers to discuss various implications for personalized medicine during one-day symposium

Four caged xanthones can inhibit growth of CCA cell lines: Research article

NARSAD honours UNC's Patrick Sullivan with 2010 Distinguished Investigator Award

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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