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Protein crucial in mediating anti-inflammatory actions of nuclear lipid receptors discovered

Researchers at the Swedish medical university Karolinska Institutet have discovered a protein that is crucial in mediating the anti-inflammatory actions of nuclear lipid receptors. The findings, published in the research journal Genes & Development, link lipid metabolism and inflammation and open up new possibilities for developing treatments of metabolic diseases associated with inflammation, such as diabetes and atherosclerosis.

17 Feb 2010

UWM engineer creates software program that foresees outcome before stem cell divides

A software program created by an engineer at the University of Wisconsin-Milwaukee (UWM) can not only predict the types of specialized cells a stem cell will produce, but also foresee the outcome before the stem cell even divides.

17 Feb 2010

Study: Researchers use genomics to decode blueprint of Plasmodium falciparum

Scientists battling malaria have earned a major victory. According to a Nature Genetics study, an international group of researchers has used genomics to decode the blueprint of Plasmodium falciparum - a strain of malaria most resistant to drugs that causes the most deaths around the world.

17 Feb 2010

Iowa State University researchers awarded 30 ARRA grants worth $16.38M

Iowa State University researchers have so far won 30 grants worth a total $16.38 million from federal agencies awarding money from the American Recovery and Reinvestment Act (ARRA).

17 Feb 2010

Study confirms link between mammographic breast density and breast cancer

A University of Melbourne study has revealed that certain breast cancer genetic variants increase mammographic density, confirming the link between mammographic breast density and breast cancer.

17 Feb 2010

First field study shows lack of exposure to morning light delays sleep in teenagers

The first field study on the impact of light on teenagers' sleeping habits finds that insufficient daily morning light exposure contributes to teenagers not getting enough sleep.

17 Feb 2010

TKS4 protein plays significant role in Frank-Ter Haar syndrome

An international team of investigators at Sanford-Burnham Medical Research Institute (Sanford-Burnham, formerly Burnham Institute for Medical Research), Nijmegen Centre for Molecular Life Sciences and other organizations have discovered that TKS4, a protein implicated in cancer metastasis, also plays a significant role in Frank-Ter Haar syndrome (FTHS), a rare fatal disorder.

17 Feb 2010

Quintiles' anatomic pathology services now available in China to help develop effective cancer treatments

Quintiles today announced the availability of anatomic pathology services through its central laboratory in Beijing, China, to help biopharmaceutical companies develop more effective cancer treatments. These services complement assay development, digital pathology and core lab offerings available through the facility to help customers comply with China’s restrictions on tissue import/export.

17 Feb 2010

Ingenuity Systems releases new IPA software for life science researchers

Ingenuity® Systems, the leading provider of information solutions for life science researchers, today announced the addition of dynamic reports, new weekly content updates, and metabolomics workflow support in the latest release of IPA® software.

16 Feb 2010

Malaria: Nose of mosquito transplanted

Scientists at Vanderbilt and Yale universities have successfully transplanted most of the "nose" of the mosquito that spreads malaria into frog eggs and fruit flies and are employing these surrogates to combat the spread of the deadly and debilitating disease that afflicts 500 million people.

16 Feb 2010

Study: Common underlying mechanism causes complex defects in brain development and function

A new study reveals that a common underlying mechanism is shared by a group of previously unrelated disorders which all cause complex defects in brain development and function. Rett syndrome (RTT), Cornelia de Lange syndrome (CdLS) and Alpha-Thalassemia mental Retardation, X-linked syndrome (ATR-X) have each been linked with distinct abnormalities in chromatin, the spools of proteins and DNA that make up chromosomes and control how genetic information is read in a cell.

16 Feb 2010

Tinnitus not a highly inherited condition, says study

Tinnitus, or ringing in the ears, does not appear to be a highly inherited condition (i.e., does not pass frequently from parents to offspring), according to a report in the February issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.

16 Feb 2010

Stem cells intentionally cut and then repair their own DNA to develop new tissues

A new study from the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa suggests that stem cells intentionally break their own DNA as a way of regulating tissue development. The study, published in Proceedings of the National Academy of Science (PNAS), could dramatically change how researchers think about tissue development, stem cells and cancer.

15 Feb 2010

Allele-specific DNA methylation a widespread phenomenon, reveals IoP study

Researchers from the Institute of Psychiatry (IoP), King's College London, have identified numerous novel regions of the genome where the chemical modifications involved in controlling gene expression are influenced by either genetic variation or the parental origin of that particular stretch of DNA. This contradicts previous assumptions that epigenetic signals are generally equal across both copies of a given region of the genome, except at a small number of known imprinted genes.

15 Feb 2010

Researchers identify defective signaling pathway that contributes to the severity of cystic fibrosis

In a study that could lead to new therapeutic targets for patients with the cystic fibrosis, a research team from the University of California, San Diego School of Medicine has identified a defective signaling pathway that contributes to disease severity.

15 Feb 2010

Researchers use $1.3M grant from NIH to study on obesity and Type 2 diabetes

A team of Northern Arizona University-led researchers is using nearly $1.3 million in new funding from the National Institutes of Health to continue with the world's longest-running study on obesity and Type 2 diabetes.

15 Feb 2010

Researchers describe the structure of ToxT that controls virulent nature of Vibrio cholerae

In a new study, Dartmouth researchers describe the structure of a protein called ToxT that controls the virulent nature of Vibrio cholerae, the bacteria that causes cholera. Buried within ToxT, the researchers were surprised to find a fatty acid that appears to inhibit ToxT, which prevents the bacteria from causing cholera.

14 Feb 2010

New project to unravel secret lives of cancer cells may help produce new cancer therapies

A team of scientists from Princeton University and The Cancer Institute of New Jersey has embarked on a major new project to unravel the secret lives of cancer cells that go dormant and self-cannibalize to survive periods of stress. The work may help produce new cancer therapies to stem changes that render cancer cells dangerous and resistant to treatment.

12 Feb 2010

Treating bacteria with insufficient levels of antibiotics leads to multidrug resistance in 'superbugs'

For years, doctors have warned patients to finish their antibiotic prescriptions or risk a renewed infection by a "superbug" that can mount a more powerful defense against the same drug. But a new study by Boston University biomedical engineers indicates that treating bacteria with levels of antibiotics insufficient to kill them produces germs that are cross-resistant to a wide range of antibiotics.

12 Feb 2010

Low doses of antibiotics may serve as active mutagens and lead to multidrug resistance

Multidrug resistant bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA) pose a major problem for patients, doctors, and the pharmaceutical industry. To combat such bacteria, it is critical to understand how resistance is developed in the first place. It is commonly thought that an incomplete course of antibiotics would lead to resistance to that particular antibiotic by allowing the bacteria to make adaptive changes under less stringent conditions.

12 Feb 2010

Genes News and Research

Protein crucial in mediating anti-inflammatory actions of nuclear lipid receptors discovered

UWM engineer creates software program that foresees outcome before stem cell divides

Study: Researchers use genomics to decode blueprint of Plasmodium falciparum

Iowa State University researchers awarded 30 ARRA grants worth $16.38M

Study confirms link between mammographic breast density and breast cancer

First field study shows lack of exposure to morning light delays sleep in teenagers

TKS4 protein plays significant role in Frank-Ter Haar syndrome

Quintiles' anatomic pathology services now available in China to help develop effective cancer treatments

Ingenuity Systems releases new IPA software for life science researchers

Malaria: Nose of mosquito transplanted

Study: Common underlying mechanism causes complex defects in brain development and function

Tinnitus not a highly inherited condition, says study

Stem cells intentionally cut and then repair their own DNA to develop new tissues

Allele-specific DNA methylation a widespread phenomenon, reveals IoP study

Researchers identify defective signaling pathway that contributes to the severity of cystic fibrosis

Researchers use $1.3M grant from NIH to study on obesity and Type 2 diabetes

Researchers describe the structure of ToxT that controls virulent nature of Vibrio cholerae

New project to unravel secret lives of cancer cells may help produce new cancer therapies

Treating bacteria with insufficient levels of antibiotics leads to multidrug resistance in 'superbugs'

Low doses of antibiotics may serve as active mutagens and lead to multidrug resistance

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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