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Women with family history of cancer need to have proper counseling, testing

In the wake of actress Angelina Jolie's public announcement that she recently underwent a preventive double mastectomy, Loma Linda University Medical Center urges women with a family history of cancer to have proper counseling and testing, if indicated, to see if they are at similar risk.

17 May 2013

Weekend reading: Volunteers in the battle with heart disease; Psychiatry without medication; Owning your genes

Psychiatrists who take time with their patients are not the norm. It's not because others don't care. Rather the system rewards efficiency, not empathy.

17 May 2013

Protein processing breakdown in endoplasmic reticulum

With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the story by reporting the discovery of a molecular chain of events in the brains of obese rats that undermined their ability to suppress appetite and to increase calorie burning.

17 May 2013

Researchers use new analysis method to determine genes that result in cell death

Lethal and rescuer genes are defined as genes that when inactivated result in cell death or enhanced cell growth, respectively. The ability to identify these genes in large-scale automated screening campaigns could lead to the discovery of valuable new drug targets.

17 May 2013

Northwestern University scientists identify gene important to morning wake-up call

Northwestern University scientists have shown a gene involved in neurodegenerative disease also plays a critical role in the proper function of the circadian clock.

17 May 2013

Scientists identify 4 genes in baboons that influence levels of bad cholesterol

Scientists at the Texas Biomedical Research Institute in San Antonio have identified four genes in baboons that influence levels of "bad" cholesterol. This discovery could lead to the development of new drugs to reduce the risk of heart disease.

17 May 2013

Study provides new evidence that genetic risk for schizophrenia associated with lower IQ

The relationship between the heritable risk for schizophrenia and low intelligence has not been clear. Schizophrenia is commonly associated with cognitive impairments that may cause functional disability. There are clues that reduced IQ may be linked to the risk for developing schizophrenia.

17 May 2013

Viewpoints: Controversy taints IRS efforts on health law; Another chance to 'gut' the overhaul in the courts; Salt wrongly accused

Even as the politicized tax enforcement scandal expands, the Internal Revenue Service continues to expand its political powers thanks to the Affordable Care Act. A larger government always creates more openings for abuse, as Americans will learn when the IRS starts auditing their health care in addition to their 1040 next year (5/14).

16 May 2013

Mayo Clinic researchers complete world's first whole exome sequence of small intestine carcinoids

Researchers at Mayo Clinic have completed the world's first whole exome sequence of small intestine neuroendocrine tumors, also known to patients and physicians as carcinoids, the most common cancer of the small bowel and one that responds poorly to chemotherapy.

16 May 2013

Study underscores new paradigm in cancer therapy

In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced pancreatic and prostate cancers.

16 May 2013

Study reveals how and why developmental genes often take inputs from 2 independent sources

Albert Erives, associate professor in the University of Iowa Department of Biology, and his graduate student, Justin Crocker, currently a postdoctoral researcher at the Howard Hughes Medical Institute Janelia Farm Research Campus, have conducted a study that reveals important and useful insights into how and why developmental genes often take inputs from two independent "morphogen concentration gradients."

16 May 2013

Researchers show a model of how cells' regulatory systems work

How cells regulate their own function by "accelerating and braking" is important basic knowledge when new intelligent medicines are being developed, or when plant cells are tweaked to produce more bioenergy.

16 May 2013

Angelina Jolie's choice underscores screening and treatment costs

News outlets report on the cost of and questions surrounding Angelina Jolie's decision to have genetic testing and then to undergo a double mastectomy as preventive surgery.

16 May 2013

Novel drug may increase the effectiveness of radiation therapy for brain cancer

A novel drug may help increase the effectiveness of radiation therapy for the most deadly form of brain cancer, report scientists at Virginia Commonwealth University Massey Cancer Center. In mouse models of human glioblastoma multiforme (GBM), the new drug helped significantly extend survival when used in combination with radiation therapy.

15 May 2013

UAB genetics and breast cancer experts respond to Angelina Jolie's preventive mastectomy

Hollywood actress Angelina Jolie, who has one of the genes linked to breast cancer, revealed that she underwent a double mastectomy earlier this year to prevent following in the footsteps of her mother and succumbing to breast cancer.

15 May 2013

IFR scientists mine the genome of C. botulinum to reveal new information about toxin genes

The toxin that causes botulism is the most potent that we know of. Eating an amount of toxin just 1000th the weight of a grain of salt can be fatal, which is why so much effort has been put into keeping Clostridium botulinum, which produces the toxin, out of our food.

15 May 2013

Vijay Tiwari from IMB receives Bruno Speck Award from Swiss Foundation of Haematological Research

Dr Vijay Tiwari, a Group Leader at the Institute of Molecular Biology (IMB) in Mainz, has been awarded the Bruno Speck Award by the Swiss Foundation of Haematological Research. The award recognises outstanding work by young scientists in the fields of haematology and stem cell research.

15 May 2013

ALKBH7 protein plays key role in controlling programmed necrosis pathway

When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ravaged their DNA.

15 May 2013

Prenatal exposure to influenza increases risk of bipolar disorder in offspring

Pregnant mothers' exposure to the flu was associated with a nearly fourfold increased risk that their child would develop bipolar disorder in adulthood, in a study funded by the National Institutes of Health.

15 May 2013

Research may help scientists learn anti-aging secrets of sacred lotus

A team of 70 scientists from the U.S., China, Australia and Japan today reports having sequenced and annotated the genome of the "sacred lotus," which is believed to have a powerful genetic system that repairs genetic defects, and may hold secrets about aging successfully.

14 May 2013

Genes News and Research

Women with family history of cancer need to have proper counseling, testing

Weekend reading: Volunteers in the battle with heart disease; Psychiatry without medication; Owning your genes

Protein processing breakdown in endoplasmic reticulum

Researchers use new analysis method to determine genes that result in cell death

Northwestern University scientists identify gene important to morning wake-up call

Scientists identify 4 genes in baboons that influence levels of bad cholesterol

Study provides new evidence that genetic risk for schizophrenia associated with lower IQ

Viewpoints: Controversy taints IRS efforts on health law; Another chance to 'gut' the overhaul in the courts; Salt wrongly accused

Mayo Clinic researchers complete world's first whole exome sequence of small intestine carcinoids

Study underscores new paradigm in cancer therapy

Study reveals how and why developmental genes often take inputs from 2 independent sources

Researchers show a model of how cells' regulatory systems work

Angelina Jolie's choice underscores screening and treatment costs

Novel drug may increase the effectiveness of radiation therapy for brain cancer

UAB genetics and breast cancer experts respond to Angelina Jolie's preventive mastectomy

IFR scientists mine the genome of C. botulinum to reveal new information about toxin genes

Vijay Tiwari from IMB receives Bruno Speck Award from Swiss Foundation of Haematological Research

ALKBH7 protein plays key role in controlling programmed necrosis pathway

Prenatal exposure to influenza increases risk of bipolar disorder in offspring

Research may help scientists learn anti-aging secrets of sacred lotus

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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