Genes News and Research

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IL-13 receptor system could play a major role in Parkinson's

Deciphering what causes the brain cell degeneration of Parkinson's disease has remained a perplexing challenge for scientists. But a team led by scientists from The Scripps Research Institute (TSRI) has pinpointed a key factor controlling damage to brain cells in a mouse model of Parkinson's disease.

20 Nov 2012

Researchers discover new gene for susceptibility to Alzheimer's disease

A large-scale international study involving French researchers from the Inserm-Institut Pasteur Lille-Universit- Lille Nord de France "Public health and molecular epidemiology of ageing-related diseases" joint research unit led by Philippe Amouyel, has just discovered a gene for susceptibility to a rare disease that causes susceptibility to a common one, Alzheimer's disease, providing evidence of the heterogeneous aetiology of Alzheimer's disease.

20 Nov 2012

Finnish researchers develop triumphant solution to predict breast cancer cells’ responses to drugs

The answer is yes. Finnish researchers have developed a triumphant solution for predicting responses of breast cancer cells to a set of cancer drugs. The prediction is based on the genomic profiles of the cancer cells. Harnessing genomic profiles of cells in choosing the best treatment is considered the holy grail of personalised medicine.

20 Nov 2012

New fiber-optic device can deliver light to the brain in 3D

A new tool for neuroscientists delivers a thousand pinpricks of light to a chunk of gray matter smaller than a sugar cube. The new fiber-optic device, created by biologists and engineers at the Massachusetts Institute of Technology (MIT) in Cambridge, is the first tool that can deliver precise points of light to a 3-D section of living brain tissue. The work is a step forward for a relatively new but promising technique that uses gene therapy to turn individual brain cells on and off with light.

19 Nov 2012

AGTR2 gene variant predicts risk for preeclampsia

Carriers of a variant of the angiotensin II receptor, type 2 gene have increased risk for preeclampsia during pregnancy if they are also overweight or obese, show study results published in Placenta.

19 Nov 2012

Overexpression of BCL6 results in transformation of neural stem cells into cortical neurons

The cerebral cortex is the most complex structure in our brain and the seat of consciousness, emotion, motor control and language. In order to fulfill these functions, it is composed of a diverse array of nerve cells, called cortical neurons, which are affected by many neurological and neuropsychiatric diseases.

19 Nov 2012

Two genetic factors strongly associated with non-syndromic sagittal craniosynostosis

An international team of geneticists, pediatricians, surgeons and epidemiologists from 23 institutions across three continents has identified two areas of the human genome associated with the most common form of non-syndromic craniosynostosis ― premature closure of the bony plates of the skull.

18 Nov 2012

HCV medications' side effects can now be replicated and observed in Petri dishes and test tubes

The adverse side effects of certain hepatitis C medications can now be replicated and observed in Petri dishes and test tubes, thanks to a research team led by Craig Cameron, the Paul Berg Professor of Biochemistry and Molecular Biology at Penn State University.

17 Nov 2012

Researchers discover health similarities between humans and pigs

An international scientific collaboration that includes two Kansas State University researchers is bringing home the bacon when it comes to potential animal and human health advancements, thanks to successfully mapping the genome of the domestic pig.

17 Nov 2012

Scientists identify cell growth pathway that is unusually active in gliomas

Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.

17 Nov 2012

Caterpillar fungi may benefit asthma patients

Research shows that cordycepin, extracted from a group of rare parasitic caterpillar fungi of the genus Cordyceps, has unusual anti-inflammatory properties that may make it a good candidate for treating conditions such as asthma and rheumatoid arthritis.

16 Nov 2012

Study links congenital kidney disease with neurodevelopmental disorders

About 10 percent of kids born with kidney defects have large alterations in their genomes known to be linked with neurodevelopmental delay and mental illness, a new study by Columbia University Medical Center (CUMC) researchers has shown.

16 Nov 2012

New pathway appears to play a major role in information processing in the brain

Scientists at The Scripps Research Institute (TSRI) have identified a new pathway that appears to play a major role in information processing in the brain. Their research also offers insight into how imbalances in this pathway could contribute to cognitive abnormalities in humans.

16 Nov 2012

GigaScience announces publication of whole-genome sequencing and analysis of Wuzhishan Pig

The international open-access journal GigaScience announces the publication of the whole-genome sequencing and analysis of the Wuzhishan Pig, an extensively inbred, miniature pig, which can serve as an excellent model for human medical research.

16 Nov 2012

AGT2R gene variant may predispose women to pre-eclampsia

New research at the University of Adelaide has revealed a genetic link in pregnant mums - and their male partners - to pre-eclampsia, a life-threatening complication during pregnancy.

16 Nov 2012

Pachytene piRNAs play an essential role in protecting post-meiotic germ cells

Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals.

16 Nov 2012

Genetic link between rheumatoid arthritis and the X chromosome

Researchers have pieced together new genetic clues to the arthritis puzzle in a study that brings potential treatments closer to reality and could also provide insights into why more women than men succumb to the disabling condition.

15 Nov 2012

Researchers identify broad patterns of gene activity that correspond to aggression

With a mate and a nest to protect, the male threespined stickleback is a fierce fish, chasing and biting other males until they go away.

15 Nov 2012

International research team discovers gene that nearly triples risk of Alzheimer's disease

A gene so powerful it nearly triples the risk of Alzheimer's disease has been discovered by an international team including researchers from Mayo Clinic. It is the most potent genetic risk factor for Alzheimer's identified in the past 20 years. The findings were reported Wednesday in the online edition of the New England Journal of Medicine.

15 Nov 2012

Braking mechanism in olfactory neurons helps generate amazing diversity of sensors in the nose

The human nose has millions of olfactory neurons grouped into hundreds of different neuron types. Each of these neuron types expresses only one odorant receptor, and all neurons expressing the same odorant receptor plug into one region in the brain, an organization that allows for specific odors to be sensed.

15 Nov 2012

Genes News and Research

IL-13 receptor system could play a major role in Parkinson's

Researchers discover new gene for susceptibility to Alzheimer's disease

Finnish researchers develop triumphant solution to predict breast cancer cells’ responses to drugs

New fiber-optic device can deliver light to the brain in 3D

AGTR2 gene variant predicts risk for preeclampsia

Overexpression of BCL6 results in transformation of neural stem cells into cortical neurons

Two genetic factors strongly associated with non-syndromic sagittal craniosynostosis

HCV medications' side effects can now be replicated and observed in Petri dishes and test tubes

Researchers discover health similarities between humans and pigs

Scientists identify cell growth pathway that is unusually active in gliomas

Caterpillar fungi may benefit asthma patients

Study links congenital kidney disease with neurodevelopmental disorders

New pathway appears to play a major role in information processing in the brain

GigaScience announces publication of whole-genome sequencing and analysis of Wuzhishan Pig

AGT2R gene variant may predispose women to pre-eclampsia

Pachytene piRNAs play an essential role in protecting post-meiotic germ cells

Genetic link between rheumatoid arthritis and the X chromosome

Researchers identify broad patterns of gene activity that correspond to aggression

International research team discovers gene that nearly triples risk of Alzheimer's disease

Braking mechanism in olfactory neurons helps generate amazing diversity of sensors in the nose

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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