Genetic News and Research

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New DNA microarray detects genetic changes differentiating cancer patients from healthy individuals

A group of researchers led by scientists from the Virginia Bioinformatics Institute at Virginia Tech have developed a new technology that detects distinct genetic changes differentiating cancer patients from healthy individuals and could serve as a future cancer predisposition test.

23 Feb 2011

Study: Antibody-directed chemotherapy may be effective for majority of younger AML sufferers

Antibody-directed chemotherapy offers improved survival to particular sub-groups of leukaemia sufferers, a Cardiff University-led study has found.

23 Feb 2011

CAMH introduces mobile research lab to study mental health, addictions in communities across Ontario

Today, the Centre for Addiction and Mental Health launched Canada's first mobile research laboratory to study mental health and addictions in communities across Ontario.

23 Feb 2011

Gilead Sciences signs definitive agreement to acquire Calistoga for $375 million

Gilead Sciences, Inc. and Calistoga Pharmaceuticals, Inc., a privately-held biotechnology company focused on the development of medicines to treat cancer and inflammatory diseases, today announced the signing of a definitive agreement pursuant to which Gilead will acquire Calistoga for $375 million.

22 Feb 2011

Why are Chlamydia and HPV major public health problems?

Chlamydia trachomatis is a bacterium that is one of the most common sexually transmitted infections in Europe. Rates in sexually active young people are commonly between 5% and 10%. The number of diagnosed cases is increasing in many European countries, in part due to increased testing and the use of more sensitive tests.

22 Feb 2011

Noninvasive test to evaluate risk of ASD in infants

A computational physicist and a cognitive neuroscientist at Children's Hospital Boston have come up with the beginnings of a noninvasive test to evaluate an infant's autism risk.

22 Feb 2011

Mutated cancer pathway studies identify therapeutic targets for congenital heart disease

Cross-disciplinary teams of scientists studying genetic pathways that are mutated in many forms of cancer, but which also cause certain forms of congenital heart disease - including hypertrophic cardiomyopathy, a thickening of the heart muscle that is the leading cause of sudden death in children and young adults -, have introduced these mutations into mice and successfully treated HCM in the lab.

22 Feb 2011

Experimental vaccine appears to protect against pneumonia

Researchers at Albert Einstein College of Medicine of Yeshiva University have developed an experimental vaccine that appears to protect against an increasingly common and particularly deadly form of pneumococcal pneumonia. Details of the new vaccine, which was tested in an animal model, are reported in a paper published today in the Journal of Infectious Diseases.

22 Feb 2011

New study: Rapamycin reverses cardiac muscle damage in LEOPARD syndrome mouse model

Congenital heart diseases affect approximately one in 100 patients, making them the most common type of birth defect and the number-one cause of pediatric deaths.

21 Feb 2011

Scientists identify new cellular mechanism underlying hydronephrosis

One of the most common congenital defects in humans - it is detected in approximately 0.5% of fetuses analyzed by routine antenatal sonography - is a kidney abnormality known as hydronephrosis. Hydronephrosis arises because the flow of urine from the kidney to the bladder is impeded.

21 Feb 2011

International study shows reprogramming cells lead to genomic aberrations

It's a discordant note in the symphony of good news that usually accompanies stem cell research announcements. Stem cells hold enormous promise in regenerative medicine, thanks to their ability to regenerate diseased or damaged tissues.

21 Feb 2011

Swedish scientist: Social, physical and mental activities can minimize risk of dementia

As the average life span becomes longer, dementia becomes more common. Swedish scientist Laura Fratiglioni has shown that everyone can minimize his or her risk of being affected. Factors from blood pressure and weight to the degree of physical and mental activity can influence cognitive functioning as one gets older.

21 Feb 2011

Experts caution against dangers of inflated expectations of genomic medicine

In the ten years since the human genetic code was mapped, expectations among scientists, health care industry, policy makers, and the public have remained high concerning the promise of genomics research for improving health.

19 Feb 2011

Life Technologies announces winners of European Ion Torrent PGM Sequencer Grants Program

Life Technologies Corporation, today announced Dr. Angel Carracedo and Dr. Mark Pallen as the winners of the European Ion Torrent Personal Genome Machine (PGM™) Sequencer Grants Program.

19 Feb 2011

Biologist investigates CAPV-EAE population for hereditary breast and ovary cancer

Between 5 % and 10 % of breast cancer cases are hereditary, arising because the patient inherits from the father or mother a mutation in a gene that is susceptible to causing the illness. BRCA1 and BRCA2 have already been identified as two of the genes to be monitored. It is estimated that 30 % of hereditary breast cancer cases are due to mutations in one of these two genes.

19 Feb 2011

Genzyme reports 3-year follow-up data from eliglustat tartrate Phase 2 trial for Gaucher disease

Genzyme Corporation today announced three-year follow-up data from patients enrolled in the phase 2 clinical trial for its investigational oral therapy for Gaucher disease type 1 known as eliglustat tartrate. Sustained or further improvements were observed across all endpoints, including bone disease, at the three-year timepoint.

19 Feb 2011

Medical students can bebefit from ACMG Summer Genetics Scholar Program

Medical students from around the country will have an opportunity to experience firsthand the new frontier of medicine in a revolutionary new genetics summer training program just announced by the American College of Medical Genetics Foundation, a prominent non-profit genetics foundation.

19 Feb 2011

Depression doesn't decline with age in addiction-prone women

Unlike alcohol abuse problems and antisocial behavior, depression doesn't decline with age in addiction-prone women in their 30s and 40s - it continues to increase, a new study led by University of Michigan Health System researchers found.

18 Feb 2011

USPTO issues two patents to VIRxSYS SMaRT RNA platform technology

VIRxSYS Corporation, a privately-held biotechnology company with proprietary RNA payload and lentiviral vector delivery platform technologies, today announced that the United States Patent and Trademark Office has issued the Company two patents for its SMaRT RNA platform technology, capable of reprogramming or repairing genes to create, increase or change protein expression.

18 Feb 2011

Cyclacel's CYC065 CDK inhibitor demonstrates potential against breast cancer resistant to trastuzumab

Cyclacel Pharmaceuticals, Inc., today announced the publication of preclinical data in the Proceedings of the National Academy of Sciences (PNAS), demonstrating that cyclin E plays a major role in making Human Epidermal growth factor Receptor 2 positive (HER2+) breast cancer resistant to trastuzumab (Herceptin®), a widely used medicine for breast cancer patients who test positive for HER2.

18 Feb 2011

Genetic News and Research

New DNA microarray detects genetic changes differentiating cancer patients from healthy individuals

Study: Antibody-directed chemotherapy may be effective for majority of younger AML sufferers

CAMH introduces mobile research lab to study mental health, addictions in communities across Ontario

Gilead Sciences signs definitive agreement to acquire Calistoga for $375 million

Why are Chlamydia and HPV major public health problems?

Noninvasive test to evaluate risk of ASD in infants

Mutated cancer pathway studies identify therapeutic targets for congenital heart disease

Experimental vaccine appears to protect against pneumonia

New study: Rapamycin reverses cardiac muscle damage in LEOPARD syndrome mouse model

Scientists identify new cellular mechanism underlying hydronephrosis

International study shows reprogramming cells lead to genomic aberrations

Swedish scientist: Social, physical and mental activities can minimize risk of dementia

Experts caution against dangers of inflated expectations of genomic medicine

Life Technologies announces winners of European Ion Torrent PGM Sequencer Grants Program

Biologist investigates CAPV-EAE population for hereditary breast and ovary cancer

Genzyme reports 3-year follow-up data from eliglustat tartrate Phase 2 trial for Gaucher disease

Medical students can bebefit from ACMG Summer Genetics Scholar Program

Depression doesn't decline with age in addiction-prone women

USPTO issues two patents to VIRxSYS SMaRT RNA platform technology

Cyclacel's CYC065 CDK inhibitor demonstrates potential against breast cancer resistant to trastuzumab

Genetics & Genomics - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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