Genetic News and Research

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Prader-Willi syndrome - new genetic clues

A new mouse model for a genetic cause of obesity has been developed by scientists at the Stanford University School of Medicine and Lucile Packard Children's Hospital.

6 Mar 2008

Alcohol may increase blood pressure to a much greater extent than previously thought

Previous observational studies have reported that heavy alcohol intake is a risk factor for hypertension but such studies may be confounded by factors such as diet, smoking, exercise levels and socio-economic position.

6 Mar 2008

Happiness in life and your genes

Happiness in life is as much down to having the right genetic mix as it is to personal circumstances according to a recent study.

6 Mar 2008

Flat, non-polypoid colorectal neoplasms linked to colorectal cancer

Flat, non-polypoid colorectal neoplasms (NP-CRNs), which may be difficult to detect, appear to be relatively common and may have a greater association with cancer compared with the more routinely diagnosed type of colorectal polyps, according to a study in the March 5 issue of JAMA.

6 Mar 2008

Genetic mutations involved in IGF-I signaling pathway influence life span

Mutations in genes governing an important cell-signaling pathway influence human longevity, scientists at the Albert Einstein College of Medicine of Yeshiva University have found.

6 Mar 2008

Chemotherapy with chemoradiation for pancreatic cancer has small survival benefit

The addition of the drug gemcitabine with chemoradiation for the treatment of patients who had surgery for pancreatic cancer was associated with a survival benefit, although this improvement was not statistically significant, according to a study in the March 5 issue of JAMA.

6 Mar 2008

Biologists discover parochial bacterial viruses

Biologists examining ecosystems similar to those that existed on Earth more than 3 billion years ago have made a surprising discovery: Viruses that infect bacteria are sometimes parochial and unrelated to their counterparts in other regions of the globe.

6 Mar 2008

Alcohol and blood pressure

A new study published in PLoS Medicine shows that individuals who drink on a regular basis have a systolic blood pressure around 7 mmHg higher than that of people who do not drink.

6 Mar 2008

Happiness is in the genes

Scientists from Scotland and Australia say being happy in life could be all about having the right genetic mix.

5 Mar 2008

Cigarette smoke prevents stem cells from becoming cartilage

A toxic pollutant spread by oil spills, forest fires and car exhaust is also present in cigarette smoke, and may represent a second way in which smoking delays bone healing, according to research presented at the annual meeting of the Orthopaedic Research Society in San Francisco.

4 Mar 2008

New genetic marker of risk for breast cancer discovered

An international group of investigators led by scientists at Memorial Sloan-Kettering Cancer Center (MSKCC) and the National Cancer Institute has identified a new genetic marker of risk for breast cancer.

4 Mar 2008

How variants of a specific gene, CAPON or NOS1AP, can disrupt normal heart rhythm

A research team from the Cedars-Sinai Heart Institute, Johns Hopkins University and China Medical University and Hospital in Taiwan have described for the first time the mechanisms by which variants of a specific gene, CAPON or NOS1AP, can disrupt normal heart rhythm.

4 Mar 2008

Bardet-Biedl syndrome provides clues on obesity, blood pressure

University of Iowa researchers have found a clue about how resistance to the hormone leptin might disrupt the brain signals that tell the body when to stop eating.

4 Mar 2008

Tiny RNA molecule found to help create skin's protective barrier

Every minute, 30,000 of our outermost skin cells die so that we can live. When they do, new cells migrate from the inner layer of the skin to the surface of it, where they form a tough protective barrier.

4 Mar 2008

Genetic variations increase risk of anxiety disorders

Massachusetts General Hospital (MGH) researchers - in collaboration with scientists at the University of California at San Diego and Yale University - have discovered perhaps the strongest evidence yet linking variation in a particular gene with anxiety-related traits.

4 Mar 2008