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Breakthrough study reveals role of histone deacetylases in inflammatory bowel disease

In a scientific breakthrough, Mount Sinai researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.

22 Apr 2024

New research identifies risk factors for dilated cardiomyopathy in genetic carriers

Dilated cardiomyopathy is the most frequent cause of heart failure in young people and is the leading cause of heart transplantation. In this disease, the heart enlarges and reduces its capacity to pump blood. People with dilated cardiomyopathy are at high risk for arrhythmias and sudden death.

22 Apr 2024

Mitochondrial depletion in axons linked to protein accumulation in neurodegenerative diseases

Researchers from Tokyo Metropolitan University have identified how proteins collect abnormally in neurons, a feature of neurodegenerative diseases like Alzheimer's.

22 Apr 2024

Insightful review explores alcohol-related liver cancer pathogenesis

While heavy drinking is a well-established risk factor for liver cancer, the specific mechanisms by which alcohol contributes to A-HCC remain unclear.

22 Apr 2024

Neurolentech signs technology access partnership with Kaerus Bioscience to advance neurodevelopmental disorder research

Kaerus Bioscience will access Neurolentech’s NDD Drug Discovery Platform to support development of its preclinical asset pipeline for numerous genetic syndromes.

From Neurolentech 22 Apr 2024

Study identifies potential strategy to diminish the devastating impacts of traumatic brain injuries

For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely.

22 Apr 2024

Public health efforts urged to reduce sodium in packaged foods

The dual role of sodium in water balance regulation and food formulation, noting its significant association with mortality due to excessive intake.

22 Apr 2024

Study links air pollution to increased colorectal cancer risk through DNA changes

Researchers reveal how air pollution increases colorectal cancer (CRC) risk through epigenetic changes, using a large-scale study and Mendelian randomization to demonstrate ambient pollution’s impact on CRC mortality and incidence in China.

21 Apr 2024

Study reveals key protein's role in balancing immune response to viral infections

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells.

18 Apr 2024

Researchers receive NIH grant to help develop gene therapy for HIV

Researchers at Washington University School of Medicine in St. Louis have received a $6.2 million grant from the National Institutes of Health (NIH) to develop a gene therapy that would modify the immune system's B cells to spur them to produce broadly neutralizing antibodies against HIV.

18 Apr 2024

Familial environment key factor in metacognition and mentalizing abilities

Twin studies have proven invaluable for teasing out the effects of both genetics and the environment on human biology.

18 Apr 2024

Siblings with unique gene mutation offer insights into type 1 diabetes treatment

Two siblings who have the only known mutations in a key gene anywhere in the world have helped scientists gain new insights that could help progress the search for new treatments in type 1 diabetes.

18 Apr 2024

New platform can deliver gene therapy precisely to specific areas of the brain

A novel approach to gene therapy is improving lives in ways once thought impossible. Researchers at The Ohio State University Wexner Medical Center and College of Medicine have developed a new platform to deliver the gene therapy precisely to specific areas of the brain.

18 Apr 2024

Genetic News and Research

Breakthrough study reveals role of histone deacetylases in inflammatory bowel disease

New research identifies risk factors for dilated cardiomyopathy in genetic carriers

Mitochondrial depletion in axons linked to protein accumulation in neurodegenerative diseases

Insightful review explores alcohol-related liver cancer pathogenesis

Neurolentech signs technology access partnership with Kaerus Bioscience to advance neurodevelopmental disorder research

Study identifies potential strategy to diminish the devastating impacts of traumatic brain injuries

Public health efforts urged to reduce sodium in packaged foods

Study links air pollution to increased colorectal cancer risk through DNA changes

Study reveals key protein's role in balancing immune response to viral infections

Researchers receive NIH grant to help develop gene therapy for HIV

Familial environment key factor in metacognition and mentalizing abilities

Siblings with unique gene mutation offer insights into type 1 diabetes treatment

New platform can deliver gene therapy precisely to specific areas of the brain

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

Study pinpoints 95 locations in the genome associated with risk of developing PTSD

Penn State study examines how a person's telomeres are affected by caloric restriction

Tracking arboviruses by nanopore sequencing of mosquitoes

Novel antibacterial discovery: Umbrella toxin particles secreted by Streptomyces

Study findings better define the genetic landscape of neuroendocrine tumors of the cervix

Discovery of DNA repair mechanism advances understanding of how human cells stay healthy

Sequencing & Genomics: Elevating Science and Healthcare eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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