Genetic Engineering News and Research

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Johns Hopkins researchers identify molecular causes of necrotizing enterocolitis in preemies

Using a mouse model of necrotizing enterocolitis -- a potentially fatal condition that causes a premature infant's gut to suddenly die -- researchers at Johns Hopkins say they have uncovered the molecular causes of the condition and its associated brain injury.

14 Dec 2018

Alzheimer's could possibly be spread via contaminated neurosurgery

Researchers have found that surgical instruments used for neurosurgery could get contaminated by the altered brain proteins that are seen in Alzheimer’s disease. These instruments are capable of spreading the condition if not treated or decontaminated properly before reuse. The study results were published in the latest issue of the journal Nature.

14 Dec 2018

Study provides new insights into molecular mechanisms underlying role of amyloid in Alzheimer's disease

A UCL-led study has confirmed that some vials of a hormone used in discontinued medical treatments contained seeds of a protein implicated in Alzheimer's disease, and are able to seed amyloid pathology in mice.s

14 Dec 2018

New discovery will improve the safety and predictability of CRISPR

Scientists have discovered a simple set of rules that can be used to precisely predict how DNA will be modified by the CRISPR gene editing technique.

13 Dec 2018

Study: Loss of tight junction barrier protein results in gastric cancer development

Tight junctions are multi-protein complexes that serve as barriers in epithelial tissues such as the skin or lining of the gut. Loss of a specific tight junction barrier protein, claudin 18, occurs in the majority of gastric cancer patients and is correlated with poor prognosis in patients with advanced gastric cancer.

13 Dec 2018

New method to visualize small-molecule interactions inside cells

Like people in a large company, proteins in cells constantly interact with each other to perform various jobs. To develop new disease therapies, researchers are trying to control these interactions with small-molecule drugs that cause specific proteins to associate more or less with their "coworkers."

13 Dec 2018

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

According to some estimates, up to one in three people around the world may experience severe anxiety in their lifetime.

12 Dec 2018

SLU researchers explore how fetal exposure to inflammation can alter immunity in newborns

Saint Louis University researchers are studying how fetal exposure to inflammation can alter immune responses after birth.

12 Dec 2018

Researchers develop biotechnological tool to produce antifungal proteins in plants

Researchers from the Spanish Research Council at the Centre for Research in Agricultural Genomics and the Institute for Plant Molecular and Cellular Biology, in collaboration with the IATA, have developed a biotechnological tool to produce, in a very efficient manner, antifungal proteins in plants.

10 Dec 2018

Russian researchers develop novel combined action drug for cancer diagnostics and treatment

Russian researchers announced the development of a combined action drug based on ionizing radiation and bacterial toxin. Their total effect appeared to be 2,200 times stronger compared to that exerted by the radiation and toxin, separately.

4 Dec 2018

Customizing Genetically Engineered Models for Specific Research Applications

In this interview conducted at SfN 2018, Philip Dubé from Taconic Biosciences, goes into detail about genetically engineered models and their importance in understanding neurodegenerative diseases.

From Taconic Biosciences, Inc. 4 Dec 2018

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

So-called CAR-T cell therapy is a promising option for treating around a fifth of patients with diffuse large B-cell lymphoma.

4 Dec 2018

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

University of North Carolina Lineberger Comprehensive Cancer Center researchers reported promising early results from a clinical study of an investigational cellular immunotherapy that used a patient's own, genetically engineered immune cells to recognize and fight Hodgkin and non-Hodgkin lymphoma cells.

4 Dec 2018

Study provides new insights into how prions enter the brain

The spread of prions to the brain does not occur by direct transmission across the blood-brain barrier, according to a study published November 29 in the open-access journal PLOS Pathogens by Annika Keller and Adriano Aguzzi of the University Hospital Zürich, and colleagues.

3 Dec 2018

Genetic Engineering News and Research

Johns Hopkins researchers identify molecular causes of necrotizing enterocolitis in preemies

Alzheimer's could possibly be spread via contaminated neurosurgery

Study provides new insights into molecular mechanisms underlying role of amyloid in Alzheimer's disease

New discovery will improve the safety and predictability of CRISPR

Study: Loss of tight junction barrier protein results in gastric cancer development

New method to visualize small-molecule interactions inside cells

Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders

SLU researchers explore how fetal exposure to inflammation can alter immunity in newborns

Researchers develop biotechnological tool to produce antifungal proteins in plants

Russian researchers develop novel combined action drug for cancer diagnostics and treatment

Customizing Genetically Engineered Models for Specific Research Applications

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

Scientists use genetically engineered immune cells to fight Hodgkin and non-Hodgkin lymphoma cells

Study provides new insights into how prions enter the brain

Scientists alleviate schizophrenic symptoms in mice

Light-activated tools allow scientists to accurately probe intracellular phase separation

Why Mosquitoes prefer some people over others: Genetic discovery

Breakthrough Alzheimer's discovery

Stand Up to Cancer supports potential approach to more efficiently target pancreatic cancer

Scientists try to develop portable systems that can quickly produce biologics on demand

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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