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New technology can rapidly analyze the metabolic state of lipids in cells

Professor Itaru Hamachi, Lecturer Tomonori Tamura, and Assistant Professor Masaki Tsuchiya of Kyoto University have developed a new technology called O-ClickFC (Organelle-selective click labeling with flow cytometry), which can, at a very high speed, analyze the metabolic state of lipids in cells.

27 Mar 2023

Biological BMI measures metabolic health more accurately

Researchers analyze longitudinal and cross-sectional changes in blood analytes associated with variations in body mass index.

23 Mar 2023

New discovery could help target the causes of aging and cancer development

A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered.

23 Mar 2023

Study finds shared genetic risk variants across different substance use disorders

By combing through genomic data of over 1 million people, scientists have identified genes commonly inherited across addiction disorders, regardless of the substance being used.

22 Mar 2023

Scientists develop genetically defined mouse models for multiple myeloma subtypes

A team of scientists led by Martin Janz and Klaus Rajewsky at the Max Delbrück Center has successfully generated genetically defined mouse models for two subtypes of multiple myeloma.

16 Mar 2023

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Researchers assessed the efficiency of a genetic decoding system for diagnosing non-small cell lung cancer (NSCLC).

16 Mar 2023

Researchers design a virus-resistant, more useful E. coli bacteria

In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.

15 Mar 2023

TbID-based proteomic profiling in meiotic cells helps identify proximate proteins in A. thaliana

During meiosis, reshuffling of genetic information between homologous chromosomes through meiotic recombination creates variable gametes and hence genetic variation in offsprings.

13 Mar 2023

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

New insights into the effects of a hormonal treatment for transgender men, discovered by Cedars-Sinai investigators, could have implications for the treatment of breast cancer.

8 Mar 2023

Study highlights the need to offer genetic testing as standard of care for people with cerebral palsy

A Geisinger meta-analysis of recent research on the genetics of cerebral palsy (CP) provides evidence that genetic testing should be offered as the standard of care for people with the disorder, similar to current recommendations for individuals with other neurodevelopmental disorders (NDD).

6 Mar 2023

Childhood adiposity associated with increased risk of recently proposed subtypes of adult-onset diabetes

New research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) is the first study to show that childhood obesity is associated with an increased risk of four of the five recently proposed subtypes of adult-onset diabetes.

28 Feb 2023

Obesity in childhood may be a risk factor for all types of adult diabetes

Child obesity is linked to increased risk of developing diabetes in adulthood, both autoimmune forms of diabetes and different forms of type 2 diabetes, a new study published in Diabetologia reports.

28 Feb 2023

Definition of low-risk WNT-pathway medulloblastoma may need to be refined, say experts

A new research perspective was published in Oncotarget's Volume 14 on February 7, 2023, entitled, "WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?"

27 Feb 2023

Novel microfluidic model mimics a rare genetic disorder

Our bodies are made up of 60,000 miles of complex pipes that play a vital role in transporting nutrients throughout our bodies, performing waste disposal, and supplying our organs with fresh oxygen and blood.

24 Feb 2023

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

Once thought incapable of encoding proteins due to their simple monotonous repetitions of DNA, tiny telomeres at the tips of our chromosomes seem to hold a potent biological function that's potentially relevant to our understanding of cancer and aging.

21 Feb 2023

HKU research advances understanding of the fundamental biological processes of gene regulation

A research team from the University of Hong Kong led by Professor Xiang David Li from the Department of Chemistry in collaboration with Dr Yuanliang Zhai from the HKU School of Biological Sciences and Dr Jason Wing Hon Wong and Dr Xiucong Bao from the HKU School of Biomedical Sciences recently made a key breakthrough in understanding how genetic information encoded in our DNA is 'read' and why errors in 'reading' such information can often lead to developmental defects or cancers.

20 Feb 2023

Scientists identify miRNAs associated with type 2 diabetes in humans

MicroRNA (miRNA) molecules in pancreatic islets have been thought to play important roles in type 2 diabetes, but until now scientists have not confidently identified which miRNAs are associated with the disease in humans.

10 Feb 2023

New compound limits the replication of influenza viruses

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to exploit this for the treatment of influenza.

9 Feb 2023

Increase in 'twisting' of retinal arteries could cause high blood pressure and heart disease

Research led by scientists at St George's, University of London has discovered 119 areas in the genome that help to determine the size and shape of blood vessels at the back of the eye, and that an increase in 'twisting' of the arteries could cause high blood pressure and heart disease.

9 Feb 2023

A single base-resolution sequencing methodology that sequences the two most common cytosine modifications in a single workflow

Researchers developed a WGS method that read four canonical DNA bases, viz., adenine (A), cytosine (C), guanine (G), and thymine (T) plus 5mC and 5hmC, epigenetic variants of unmodified C to yield an accurate six-letter digital readout in a single workflow.

9 Feb 2023

Genetic Information News and Research

New technology can rapidly analyze the metabolic state of lipids in cells

Biological BMI measures metabolic health more accurately

New discovery could help target the causes of aging and cancer development

Study finds shared genetic risk variants across different substance use disorders

Scientists develop genetically defined mouse models for multiple myeloma subtypes

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Researchers design a virus-resistant, more useful E. coli bacteria

TbID-based proteomic profiling in meiotic cells helps identify proximate proteins in A. thaliana

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

Study highlights the need to offer genetic testing as standard of care for people with cerebral palsy

Childhood adiposity associated with increased risk of recently proposed subtypes of adult-onset diabetes

Obesity in childhood may be a risk factor for all types of adult diabetes

Definition of low-risk WNT-pathway medulloblastoma may need to be refined, say experts

Novel microfluidic model mimics a rare genetic disorder

Simple blood tests for telomeric protein could provide a valuable screen for certain cancers

HKU research advances understanding of the fundamental biological processes of gene regulation

Scientists identify miRNAs associated with type 2 diabetes in humans

New compound limits the replication of influenza viruses

Increase in 'twisting' of retinal arteries could cause high blood pressure and heart disease

A single base-resolution sequencing methodology that sequences the two most common cytosine modifications in a single workflow

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