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New study identifies 40 genes susceptible to migraine

Migraine is one of the most common neurological disorders and it affects 1 out of 7 people in the world. Painful and incapacitating, it has multi-factor origins, with the participation of environmental triggering factors and several altered genes in each individual.

23 Jun 2016

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Few threats to public health are as perilous as cigarette smoking, with more than 435,000 Americans dying each year of tobacco-related pulmonary illnesses such as chronic obstructive pulmonary disease (COPD).

22 Jun 2016

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

The protein complex that holds strands of DNA in compact spools partially disassembles itself to help genes reveal themselves to specialized proteins and enzymes for activation, according to Rice University researchers and their colleagues.

22 Jun 2016

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

Scientists at the University of Massachusetts Medical School have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication.

22 Jun 2016

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

Chronic pain is one of the most prevalent, disabling and expensive public health crises in the United States. It affects more than 100 million Americans, with annual costs estimated at $635 billion, says a 2014 report from the American Pain Society.

22 Jun 2016

VUMC researchers aim to decode genetic underpinnings of human immune system

Researchers at Vanderbilt University Medical Center this month began recruiting volunteers to participate in a clinical trial aimed at decoding the human "immunome," the genetic underpinnings of the immune system.

22 Jun 2016

Experts use next-generation genetic sequencing to diagnose suspected brain infections

In a proof-of-principle study, a team of physicians and bioinformatics experts at Johns Hopkins reports they were able to diagnose or rule out suspected brain infections using so called next-generation genetic sequencing of brain tissue samples.

21 Jun 2016

Researchers identify 38 independent genomic regions linked to migraine

The results of the largest genetic study on migraine thus far were published online in the journal Nature Genetics today, June 20. The study was based on DNA samples of 375,000 European, American and Australian participants. Almost 60,000 of them suffer from migraine.

21 Jun 2016

TUM scientists identify four new risk genes altered in MS patients

Scientists of the Technical University of Munich and the Max Planck Institute of Psychiatry have identified four new risk genes that are altered in German patients with multiple sclerosis (MS).

20 Jun 2016

Illumina signs initial customer deals for new Global Screening Array

Illumina, Inc. today announced that it has signed deals with 12 customers for its new Infinium Global Screening Array (GSA).

From Illumina, Inc. 20 Jun 2016

Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Low levels of BPA exposure may be considered safe, but new research published online in The FASEB Journal, suggests otherwise. In the report, researchers from Yale show that the genome is permanently altered in the uterus of mice that had been exposed to BPA during their fetal development.

17 Jun 2016

Study provides valuable insight into biology of tumours in early stages of cancer

Bladder cancer is a frequent disease affecting approximately 1,900 persons in Denmark annually. A high number of these patients only have superficial tumours in the bladder when the disease is diagnosed.

17 Jun 2016

Absence of one specific species of gut bacteria causes autism-related social deficits in mice

The absence of one specific species of gut bacteria causes social deficits in mice, researchers at Baylor College of Medicine report June 16 in Cell. By adding this bacterial species back to the guts of affected mice, the researchers were able to reverse some of the mice's behavioral deficits, which are reminiscent of symptoms of autism spectrum disorders (ASDs) in humans.

17 Jun 2016

RVFV uses cancer pathway to hijack host cell and cause infection

Viruses can't live without us -- literally. As obligate parasites, viruses need a host cell to survive and grow. Scientists are exploiting this characteristic by developing therapeutics that close off pathways necessary for viral infection, essentially stopping pathogens in their tracks.

17 Jun 2016

Scientists identify lipodystrophy-causing mutation in a single family

Lipodystrophy syndromes are characterized by an abnormal distribution of adipose tissue and metabolic dysfunction. These disorders are rare and the underlying genetic abnormalities that lead to altered fat distribution are not fully known.

16 Jun 2016

Scientists develop new software program that can help compare large amounts of metagenomes

Scientists from ITMO University, the Federal Research and Clinical Centre of Physical-Chemical Medicine and MIPT have developed a software program enabling them to quickly compare sets of DNA of microorganisms living in different environments. The researchers have already suggested exactly how the new program could be applied in practice.

16 Jun 2016

Researchers highlight gene loss as potential process of genetic change, evolutionary adaption

"Loss is nothing else but change and change is nature's delight" says the quote by the philosopher and emperor Marcus Aurelius, which opens the scientific article that analyses the gene loss phenomenon and its impact on the evolution of living beings.

16 Jun 2016

Genome News and Research

New study identifies 40 genes susceptible to migraine

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Researchers reveal DNA unwrapping can happen asymmetrically to expose specific genes

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

Drexel University researchers aim to identify new molecular mechanisms involved in chronic pain

VUMC researchers aim to decode genetic underpinnings of human immune system

Experts use next-generation genetic sequencing to diagnose suspected brain infections

Researchers identify 38 independent genomic regions linked to migraine

TUM scientists identify four new risk genes altered in MS patients

Illumina signs initial customer deals for new Global Screening Array

Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Study provides valuable insight into biology of tumours in early stages of cancer

Absence of one specific species of gut bacteria causes autism-related social deficits in mice

RVFV uses cancer pathway to hijack host cell and cause infection

Scientists identify lipodystrophy-causing mutation in a single family

Scientists develop new software program that can help compare large amounts of metagenomes

Researchers highlight gene loss as potential process of genetic change, evolutionary adaption

Penn researchers help identify unique characteristics of reserve stem cells

Prospective biobank studies with genetic data can help improve drug development, reduce costs

New and inexpensive technique could help meet global demands for malaria drug

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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