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Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

A team of researchers has reported a novel method for tracking CD4+ T cells in people infected with HIV. CD4+ T cells are critical for immune defense against an array of pathogens and are a primary target of HIV. In the study, researchers used a unique, replication-incompetent (defective) form of HIV identified in a patient in the early 1990s.

4 Feb 2014

Researchers develop antibiotic "smart bomb" that can identify specific strains of bacteria

Researchers from North Carolina State University have developed a de facto antibiotic "smart bomb" that can identify specific strains of bacteria and sever their DNA, eliminating the infection. The technique offers a potential approach to treat infections by multi-drug resistant bacteria.

31 Jan 2014

Novel approaches could lead researchers to develop new vaccine for East Coast fever, malaria

The Nairobi-based International Livestock Research Institute announced today that a global consortium supported by the Bill & Melinda Gates Foundation has been formed to develop a new vaccine against a disease that's devastating cattle herds in sub-Saharan Africa. This highly advanced cattle vaccine project could also help malaria and cancer research in humans.

31 Jan 2014

UC San Diego researchers uncover causes for hereditary spastic paraplegia

In a study published in the January 31, 2014 issue of Science, an international team led by scientists at the University of California, San Diego School of Medicine report doubling the number of known causes for the neurodegenerative disorder known as hereditary spastic paraplegia. HSP is characterized by progressive stiffness and contraction of the lower limbs and is associated with epilepsy, cognitive impairment, blindness and other neurological features.

31 Jan 2014

Researchers study how epigenetic alterations contribute to age-related increases in breast cancer risk

Age is a key risk factor for breast cancer. A recent study by researchers from the Dartmouth-Hitchcock Norris Cotton Cancer Center, "Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation," examines the connection between cancer and the aging process to see if epigenetic DNA alterations might contribute to age-related increases in breast cancer risk.

31 Jan 2014

TCGA Research Network identify new potential therapeutic targets for major form of bladder cancer

Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified new potential therapeutic targets for a major form of bladder cancer, including important genes and pathways that are disrupted in the disease.

30 Jan 2014

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

The once sketchy landscape of the molecular defects behind bladder cancer now resembles a road map to new, targeted treatments thanks to the unified efforts of scientists and physicians at 40 institutions.

30 Jan 2014

Bladder, lung cancers are marked by shared differences in genetics that control cell cycle

A University of Colorado Cancer Center study published in the journal PLoS ONE shows that bladder and lung cancers are marked by shared differences in the genetics that control the cell cycle.

30 Jan 2014

Researchers discover potential treatment for viral infection that causes illnesses in children

Researchers have discovered a potential treatment for a viral infection that causes potentially fatal brain swelling and paralysis in children. The findings also point to possible treatments for related viruses including those that cause "common cold" symptoms.

29 Jan 2014

Susceptible loci identified for bipolar I disorder in Taiwanese

Researchers have identified three genetic loci that may be linked to bipolar I disorder risk in Taiwanese individuals.

29 Jan 2014

BD announces commercial availability of CE-marked PAXgene Blood DNA Tube in Europe

BD, a leading global medical technology company, today announced the commercial availability of the CE-marked PAXgene Blood DNA Tube in Europe. The PAXgene Blood DNA Tube is the first blood collection tube designed specifically for in vitro diagnostic (IVD) genomic DNA testing. The product was developed by PreAnalytiX GmbH, a joint venture between BD and QIAGEN.

From BD (Becton, Dickinson and Company) 28 Jan 2014

Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

In normal development, all cells turn off genes they don’t need, often by attaching a chemical methyl group to the DNA, a process called methylation. Historically, scientists believed methyl groups could only stick to a particular DNA sequence: a cytosine followed by a guanine, called CpG. But in recent years, they have been found on other sequences, and so-called non-CpG methylation has been found in stem cells, and in neurons in the brain.

28 Jan 2014

Researchers discover unusually large bacteriophage that infects anthrax bacterium

From a zebra carcass on the plains of Namibia in Southern Africa, an international team of researchers has discovered a new, unusually large virus (or bacteriophage) that infects the bacterium that causes anthrax.

28 Jan 2014

GenePeeks receives patent for developing innovative algorithms to create hypothetical "digital babies"

GenePeeks, Inc., a genetic technology company focused on pre-conception risk prediction, announced today it has been issued patent No. 8,620,594, titled "Method and System for Generating a Virtual Progeny Genome," by the United States Patent and Trademark Office.

28 Jan 2014

Jackson Laboratory associate professor receives grant to study gene regulation at RNA level

Jackson Laboratory Associate Professor Jeffrey Chuang, Ph.D., has been awarded a two-year grant totaling $519,750 from the National Human Genome Research Institute for his studies of how RNA (molecules vital to protein formation in cells) interacts with proteins to change how genes are expressed.

27 Jan 2014

Large-scale analysis of over 20 tumor types increases catalog of cancer genes by 25%

A landmark study across many cancer types reveals that the universe of cancer mutations is much bigger than previously thought. By analyzing the genomes of thousands of patients' tumors, a Broad Institute-led research team has discovered many new cancer genes - expanding the list of known genes tied to these cancers by 25 percent. Moreover, the study shows that many key cancer genes still remain to be discovered.

25 Jan 2014

American Humane and TGen uncover genetic basis of obsessive-compulsive disorder in dogs

Every year, one out of every 88 children in the United States is diagnosed with some form of autism, with these numbers steadily rising over the last decade. Alarmingly, it is believed that now one of every 54 young boys has some form of the disease.

24 Jan 2014

Extracts from birch tree helps damaged skin around wounds to regenerate more quickly

Extracts from the birch tree have served for centuries as a traditional means of helping the damaged skin around wounds to regenerate more quickly. Prof. Dr. Irmgard Merfort from the Institute of Pharmaceutical Sciences of the University of Freiburg and her team have now explained the molecular mechanism behind the wound-healing effect of an extract from the outer white layer of the tree's bark.

24 Jan 2014

ACMG’s Genomics Annual Clinical Genetics Meeting showcases latest breakthroughs in genetics research

Do you cover genetics, genomics, healthcare or medicine? The media are invited to register now for the American College of Medical Genetics and Genomics Annual Clinical Genetics Meeting, March 25-29, 2014 at the Nashville Convention Center.

23 Jan 2014

Researchers discover new gene involved in severe childhood epilepsy

A European consortium of epilepsy researchers has reported the discovery of a new gene involved in severe childhood epilepsy. Using a novel combination of technologies, including trio exome sequencing of patient/parental DNA and genetic studies in the tiny larvae of zebrafish, the EuroEPINOMICS RES consortium found that mutations in the gene CHD2 are responsible for a subset of epilepsy patients with symptoms similar to Dravet syndrome - a severe form of childhood epilepsy that is in many patients resistant to currently available anti-epileptic drugs.

23 Jan 2014

Genome News and Research

Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

Researchers develop antibiotic "smart bomb" that can identify specific strains of bacteria

Novel approaches could lead researchers to develop new vaccine for East Coast fever, malaria

UC San Diego researchers uncover causes for hereditary spastic paraplegia

Researchers study how epigenetic alterations contribute to age-related increases in breast cancer risk

TCGA Research Network identify new potential therapeutic targets for major form of bladder cancer

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

Bladder, lung cancers are marked by shared differences in genetics that control cell cycle

Researchers discover potential treatment for viral infection that causes illnesses in children

Susceptible loci identified for bipolar I disorder in Taiwanese

BD announces commercial availability of CE-marked PAXgene Blood DNA Tube in Europe

Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

Researchers discover unusually large bacteriophage that infects anthrax bacterium

GenePeeks receives patent for developing innovative algorithms to create hypothetical "digital babies"

Jackson Laboratory associate professor receives grant to study gene regulation at RNA level

Large-scale analysis of over 20 tumor types increases catalog of cancer genes by 25%

American Humane and TGen uncover genetic basis of obsessive-compulsive disorder in dogs

Extracts from birch tree helps damaged skin around wounds to regenerate more quickly

ACMG’s Genomics Annual Clinical Genetics Meeting showcases latest breakthroughs in genetics research

Researchers discover new gene involved in severe childhood epilepsy

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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