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NIH awards BU $1.6M grant to target protein-protein interactions with synthetic organic drugs

An interdisciplinary team of Boston University professors is launching a project to develop new ways to target protein-protein interactions with synthetic organic drugs. Financed by a four-year $1.6 million grant from the National Institutes of Health, the goal is to develop new approaches for discovering "drug-like" small molecule inhibitors against challenging protein-protein interaction (PPI) interfaces.

27 Jul 2010

Illumina launches TruSeq SBS Sequencing kit

Illumina, Inc. today announced the launch of its TruSeq SBS Sequencing kit that will enable high-quality paired end reads of 150 base pairs (bp), increase the output of high-quality base calls, and enhance throughput to greater than 95 Gigabases (Gb) of high-quality base pairs per run on Illumina's Genome Analyzer (GA) sequencing system.

From Illumina, Inc. 26 Jul 2010

Highlights on reasoning behind MRC's negative decision on funding of IVF

Thirty-two years ago today, the world's first baby was born after in vitro fertilisation. However, the work that led to the birth of Louise Brown on 25 July 1978 had to be privately funded after the UK's Medical Research Council decided in 1971 against providing the Cambridge physiologist Robert Edwards and the Oldham gynaecologist Patrick Steptoe with long-term financial support. Today, an intriguing paper published in Europe's leading reproductive medicine journal Human Reproduction reveals for the first time the reasoning behind the MRC's much-criticised decision.

26 Jul 2010

Maven Semantic announces updates to Bioinformatics medical professionals database

Maven Semantic announces updates to their Bioinformatics database.

23 Jul 2010

Human Genome Sciences second-quarter revenues increase to $38.8 million

Human Genome Sciences, Inc. today announced financial results for the quarter ended June 30, 2010, and provided highlights of recent key developments.

23 Jul 2010

Genomics researchers study role of protein in metabolic disorders, heart disease

Studying a protein already known to play an important role in type 2 diabetes and cancer, genomics researchers have discovered that it may have an even broader role in disease, particularly in other metabolic disorders and heart disease. In finding unsuspected links to other disease-related genes, the scientists may have identified future targets for drug treatments.

22 Jul 2010

TCF7L2 protein may play important role in heart disease, other metabolic disorders: Researchers

22 Jul 2010

Cultivated cucumber, melon originated in Asia and Australia

Sites of origin and regions of domestication of many of our most important cultivated plants are still unknown. The botanical genus Cucumis, to which both the cucumber (Cucumis sativus) and the honeydew melon (C. melo) belong, was long thought to have originated and diversified in Africa, because many wild species of Cucumis are found there. "A molecular genetic analysis has now shown that the wild populations that gave rise to melons and cucumbers originated in Asia", says LMU botanist Professor Susanne Renner.

22 Jul 2010

Affymetrix second-quarter total revenue decreases to $71.7 million

Affymetrix, Inc., today reported its operating results for the second quarter of 2010. Total revenue for the quarter was $71.7 million, in line with previously announced expectations, as compared to total revenue of $81.6 million in the second quarter of 2009.

22 Jul 2010

Buffer among metbolism pathways induces cancer suppressing gene mutation: Research

Eighty years ago, the medical establishment believed cancer was caused by a dysfunction of metabolism, but the idea went out of vogue. Now, scientists are again looking at metabolism and its role in cancer and other common diseases. Metabolism is a highly connected network of reactions that are arranged in parallel and interacting pathways. Such parallelism can mask how genes are linked with disease traits and make it difficult to treat conditions.

22 Jul 2010

Affymetrix introduces Axiom Custom Genotyping Arrays

Affymetrix, Inc. today announced that it has launched Axiom™ Custom Genotyping Arrays, the newest addition to the Axiom Genotyping Solution. Researchers can now leverage Affymetrix' Axiom Genomic Database, the world's largest collection of validated common and rare SNPs, to create custom arrays containing 50,000 to as many as 2.6 million SNPs. This inherent flexibility allows researchers to conduct genome-wide association, replication, fine mapping, and candidate gene studies on a single platform.

21 Jul 2010

Researchers receive $12M NCI grant to identify biological pathways that lead to prostate cancer risk

Researchers at the USC Norris Comprehensive Cancer Center have received a $12 million National Cancer Institute grant to lead a multi-institution international project aimed at identifying new biological pathways critical to the development and potential treatment of prostate cancer.

21 Jul 2010

ARUP enters partnership to offer deCODE's DNA-based prostate cancer risk assessment test

deCODE genetics and ARUP Laboratories today announced a partnership through which ARUP will offer deCODE's DNA-based prostate cancer risk assessment test to its clients nationwide.

20 Jul 2010

Researchers reveal findings on restricted lineage of iPS cells

Adult cells that have been reprogrammed into induced pluripotent stem cells (iPS cells) do not completely let go of their past, perhaps limiting their ability to function as a less controversial alternative to embryonic stem cells for basic research and cell replacement therapies, according to researchers at Children's Hospital Boston, John Hopkins University and their colleagues

20 Jul 2010

New approach to understand different cancer subtypes

An international team led by St. Jude Children's Research Hospital scientists finds unique combinations of cells and mutations lie at the heart of cancer subgroup revealed for the first time in a pediatric brain tumor

20 Jul 2010

Cellectis bioresearch introduces new technology to develop cell-based assays for HTS studies

Cellectis bioresearch, a specialist in genome customization and a subsidiary of Cellectis, today announced the publication of a scientific study describing a novel method, based on meganuclease-driven targeted integration, for the generation of stable cell lines compatible with high throughput screening (HTS).The study demonstrated Cellectis bioresearch's technology to be faster, more reliable and efficient in deriving cell-based assays for HTS studies than classical methods.

20 Jul 2010

Researchers discover new gene regulation, DNA behavior of breast cancer cells

Cancer researchers have discovered a previously unknown type of gene regulation and DNA behavior in breast cancer cells that may lead to better insight about environmental exposure to estrogen-like compounds. A new study, published in the journal Genome Research by researchers at The Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James), provides the first evidence that cells can regulate many genes at once by looping their DNA, contributing to cancer when it goes awry. In this study, the gene regulation was discovered in breast cancer cells as a response to the hormone estrogen and resulted in the silencing of 14 genes at one time.

20 Jul 2010

Researchers discover genetic explanation for non-diabetic kidney disease in African-Americans

Kidney disease is a growing public health problem, with approximately half a million individuals in the United States requiring dialysis treatments to replace the function of their failed kidneys. The problem is particularly acute among African-Americans, whose rates of kidney disease are four times higher than those of European Americans.

20 Jul 2010

Researchers develop new method for producing image of individual DNA molecules' genetic make-up

A completely new method for producing an image of individual DNA molecules' genetic make-up has been developed by researchers in Sweden and Denmark. The results are published in the latest issue of the journal Proceedings of the National Academy of Sciences of the USA (PNAS).

19 Jul 2010

InformedDNA named finalist for Best Practices in Health Care Consumer Empowerment and Protection Awards

Informed Medical Decisions, Inc. (InformedDNA) has been selected as one of 30 finalists for the Best Practices in Health Care Consumer Empowerment and Protection Awards. URAC, the nation's leading accreditation organization, will honor the finalists during their 11th Annual Quality Summit, October 5-7, 2010 in Chicago, IL.

17 Jul 2010

Genome News and Research

NIH awards BU $1.6M grant to target protein-protein interactions with synthetic organic drugs

Illumina launches TruSeq SBS Sequencing kit

Highlights on reasoning behind MRC's negative decision on funding of IVF

Maven Semantic announces updates to Bioinformatics medical professionals database

Human Genome Sciences second-quarter revenues increase to $38.8 million

Genomics researchers study role of protein in metabolic disorders, heart disease

TCF7L2 protein may play important role in heart disease, other metabolic disorders: Researchers

Cultivated cucumber, melon originated in Asia and Australia

Affymetrix second-quarter total revenue decreases to $71.7 million

Buffer among metbolism pathways induces cancer suppressing gene mutation: Research

Affymetrix introduces Axiom Custom Genotyping Arrays

Researchers receive $12M NCI grant to identify biological pathways that lead to prostate cancer risk

ARUP enters partnership to offer deCODE's DNA-based prostate cancer risk assessment test

Researchers reveal findings on restricted lineage of iPS cells

New approach to understand different cancer subtypes

Cellectis bioresearch introduces new technology to develop cell-based assays for HTS studies

Researchers discover new gene regulation, DNA behavior of breast cancer cells

Researchers discover genetic explanation for non-diabetic kidney disease in African-Americans

Researchers develop new method for producing image of individual DNA molecules' genetic make-up

InformedDNA named finalist for Best Practices in Health Care Consumer Empowerment and Protection Awards

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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