Genome Editing News and Research

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Four-part small-molecule cocktail can prevent cellular stress

Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.

4 May 2021

Novel platform has potential to detect many disease-related biomarkers in just one test

Most conventional molecular diagnostics usually detect only a single disease-related biomarker. Great examples are the PCR tests currently used to diagnose COVID-19 by detecting a specific sequence from SARS-CoV-2.

28 Apr 2021

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

In their review paper recently published in the Indian Journal of Clinical Biochemistry, a group of authors discusses currently available and forthcoming CRISPR-based diagnostic assays, as well as the possibility of using the CRISPR/Cas system as a salient treatment or prevention strategy in the fight against coronavirus disease 2019 (COVID-19).

25 Apr 2021

Collaborative research could expedite or eliminate the need to manually adjust bioproduction process

Much of common pharmaceutical development today is the product of laborious cycles of tweaking and optimization.

21 Apr 2021

New approach to scale up genome editing in tiny worms

Understanding the effects of specific mutations in gene regulatory regions - the sections of DNA and RNA that turn genes on and off - is important to unraveling how the genome works, as well as normal development and disease.

13 Apr 2021

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells.

30 Mar 2021

Amino acids signaling controls whole-body glucose homeostasis, study shows

Amino acids are a major nutrient type for humans and are used as building blocks and a source of energy for cells.

16 Mar 2021

Optimized nano-micelles can induce efficient genome editing in the mouse brain

The research group of Deputy Principal Research Scientist Dr. Satoshi Uchida (Associate Professor, Kyoto Prefectural University of Medicine) at the Innovation Center of NanoMedicine (Director General: Prof. Kazunori Kataoka, Location: Kawasaki-Japan, Abbreviation: iCONM) reported that optimized nano-micelles can induce efficient genome editing in the mouse brain.

12 Mar 2021

Optimized nano-micelles can induce efficient genome editing in the mouse brain

12 Mar 2021

Unique nanoparticles can package and deliver gene-editing machinery to the liver

The genome editing technology CRISPR has emerged as a powerful new tool that can change the way we treat disease. The challenge when altering the genetics of our cells, however, is how to do it safely, effectively, and specifically targeted to the gene, tissue and organ that needs treatment.

2 Mar 2021

Researchers find a way to improve deletion efficiency of new genome-editing tool

CRISPR deletion (CRISPR-del) is a new genome editing tool that can delete or cut out certain pieces of DNA in living cells with surgical precision.

17 Feb 2021

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

A new preprint research paper posted to the bioRxiv server provides a greater understanding of the aspect of humoral immunity against the virus – the plasma cells that pour out a flood of specific antibodies targeting various epitopes on the pathogen.

16 Feb 2021

Modified CRISPR/Cas9 complex targets specific histones

Finding a needle in a haystack is hard enough. But try finding a specific molecule on the needle.

9 Feb 2021

CRISPR genomic editing to obtain more productive and nutritive plant varieties

New study by the IBMCP of the UPV university facilitates the use of the CRISPR genomic editing technique on plants.

8 Feb 2021

New genome editing technology could pave way for non-viral delivery systems

Researchers from Peter the Great St.Petersburg Polytechnic University (SPbPU) in collaboration with colleagues from Belgium take a step in the development of genome editing technology.

3 Feb 2021

Researchers use SARS-CoV-2 to bioengineer universal vaccine platform

Using SARS-CoV-2, a team of scientists from the United States has recently developed a bioengineered bacteriophage T4 nanoparticle structure using CRISPR technology that can be used as a universal platform to produce vaccines.

21 Jan 2021

Gene editing shows potential to correct mutations causing inherited retinal degeneration

Gene editing therapies, including CRISPR-Cas systems, offer the potential to correct mutations causing inherited retinal degenerations, a leading cause of blindness.

20 Jan 2021

Researchers create a molecular catalog that describes different types of neurons

Retinal ganglion cells (RGCs) are the bottleneck through which all visual impressions flow from the retina to the brain. A team from the Max Planck Institute of Neurobiology, University of California Berkeley and Harvard University created a molecular catalog that describes the different types of these neurons.

24 Dec 2020

Novel 3D maps show how genes interact in several types of immune cells

The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease.

22 Dec 2020

Pig stem cells offer a new way to grow human organs for transplantation

In a new paper published in Stem Cell Reports, Bhanu Telugu and co-inventor Chi-Hun Park of the University of Maryland (UMD) Department of Animal and Avian Sciences show for the first time that newly established stem cells from pigs, when injected into embryos, contributed to the development of only the organ of interest (the embryonic gut and liver), laying the groundwork for stem cell therapeutics and organ transplantation.

18 Dec 2020

Genome Editing News and Research

Four-part small-molecule cocktail can prevent cellular stress

Novel platform has potential to detect many disease-related biomarkers in just one test

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

Collaborative research could expedite or eliminate the need to manually adjust bioproduction process

New approach to scale up genome editing in tiny worms

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Amino acids signaling controls whole-body glucose homeostasis, study shows

Optimized nano-micelles can induce efficient genome editing in the mouse brain

Optimized nano-micelles can induce efficient genome editing in the mouse brain

Unique nanoparticles can package and deliver gene-editing machinery to the liver

Researchers find a way to improve deletion efficiency of new genome-editing tool

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

Modified CRISPR/Cas9 complex targets specific histones

CRISPR genomic editing to obtain more productive and nutritive plant varieties

New genome editing technology could pave way for non-viral delivery systems

Researchers use SARS-CoV-2 to bioengineer universal vaccine platform

Gene editing shows potential to correct mutations causing inherited retinal degeneration

Researchers create a molecular catalog that describes different types of neurons

Novel 3D maps show how genes interact in several types of immune cells

Pig stem cells offer a new way to grow human organs for transplantation

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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