Genomic News and Research

RSS

Scientists identify timing of major metabolic shift in developing neurons

Our brains can survive only for a few minutes without oxygen. Salk Institute researchers have now identified the timing of a dramatic metabolic shift in developing neurons, which makes them become dependent on oxygen as a source of energy.

13 Jul 2016

International project to develop globally accessible bank of new cancer cell models for research

An international project to develop a large, globally accessible bank of new cancer cell culture models for the research community launched today.

12 Jul 2016

Gut bacteria can help predict susceptibility to rheumatoid arthritis

The bacteria in your gut do more than break down your food. They also can predict susceptibility to rheumatoid arthritis, suggests Veena Taneja, Ph.D., an immunologist at Mayo Clinic's Center for Individualized Medicine. Dr. Taneja recently published two studies — one in Genome Medicine and one in Arthritis and Rheumatology — connecting the dots between gut microbiota and rheumatoid arthritis.

11 Jul 2016

Researchers receive $9 million grant to develop novel platform to quickly identify new antibiotics

In September 2014, President Obama issued an executive order for "Combating Antibiotic- Resistant Bacteria." Why the urgency? The Centers for Disease Control and Prevention, the order noted, "estimates that annually at least 2 million illnesses and 23,000 deaths are caused by antibiotic- resistant bacteria in the United States alone."

11 Jul 2016

JAX researchers find precise, reliable way to identify leukemia cells of origin

Every cancer starts with a single cell, and Jackson Laboratory researchers have found a precise and reliable way -- whole-genome profiling of open chromatin -- to identify the kind of cell that leads to a given case of leukemia, a valuable key to cancer prognosis and outcome.

11 Jul 2016

NIH selects VUMC to play foundational role in PMI Cohort Program

Vanderbilt University Medical Center has been chosen by the National Institutes of Health to be the Data and Research Support Center for the Precision Medicine Initiative Cohort Program, a landmark study of genetic, environmental and lifestyle factors affecting the health of a million or more people, federal officials have announced.

11 Jul 2016

Five-year NIH grant awarded to four NYC medical centers for PMI Cohort Program

Columbia University Medical Center and Weill Cornell Medicine, in collaboration with NewYork-Presbyterian and NYC Health + Hospitals/Harlem, have been awarded a grant from the NIH for approximately $4 million in fiscal year 2016 to enroll participants in the Cohort Program of President Barack Obama's Precision Medicine Initiative (PMI)—a large-scale research effort to improve our ability to prevent and treat disease based on individual differences in lifestyle, environment and genetics.

11 Jul 2016

Molecule thought to indicate good cancer prognosis can have dark side, research shows

A molecule which, for the last 20 years has been believed to be an indicator of good prognosis in tumours has been shown to have a dark side by new research from The Universities of Manchester, Athens and collaborators, recently published in Nature Cell Biology.

8 Jul 2016

Scientists identify set of genes that could predict clinical outcomes in patients with FLT3-ITD AML

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore have identified a set of genes, including DNMT3A, that could potentially be used to predict clinical outcomes of patients who suffer from a type of Acute Myeloid Leukemia (AML) associated with an FLT3 internal tandem duplication (FLT3-ITD) mutation.

8 Jul 2016

Germline genetic testing necessary for men with metastatic prostate cancer

Men with metastatic prostate cancer should be considered for germline genetic testing of DNA repair genes, regardless of age or family history, according to a team of researchers from Memorial Sloan Kettering Cancer Center, Fred Hutchinson Cancer Research Center, Dana-Farber Cancer Institute, University of Washington School of Medicine, University of Michigan, and the Institute of Cancer Research Royal Marsden Hospital.

8 Jul 2016

Researchers discover mechanism of gene silencing in hormone-dependent breast cancer cells

Sometimes, the silencing of a gene is as important as its activation. Nonetheless, up to now, most studies on hormone-mediated gene regulation have focused on researching the factors that influence the activation of certain genes. Little attention has been paid to gene silencing.

8 Jul 2016

TSRI awarded $20 million for first year of precision medicine initiative cohort program

As part of the most ambitious medical research program in the history of American medicine, The Scripps Research Institute (TSRI) has received an initial award of $20 million for its role in a national precision medicine initiative, the National Institutes of Health (NIH) announced today.

8 Jul 2016

New study to investigate how genetic factors contribute to breast cancer disparities

The largest study ever to investigate how genetic and biological factors contribute to breast cancer risk among black women launched today.

7 Jul 2016

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Precise predictions of whether a tumor is likely to spread would help clinicians and patients choose the best course of treatment. But current methods fall short of the precision needed.

6 Jul 2016

LouLou Foundation, ODC announce 11 new grants for research on CDKL5 deficiency

LouLou Foundation and the Orphan Disease Center (ODC) in the Perelman School of Medicine at the University of Pennsylvania are pleased to announce the award of 11 new research grants into CDKL5 deficiency - a rare X-chromosome-linked genetic disorder that causes severe neuro-developmental impairment and early-onset, difficult-to-control seizures.

5 Jul 2016

Novel technique could help discover genes linked to complex traits in any animal model

Mice are one of the most commonly used laboratory organisms, widely used to study everything from autism to infectious diseases. Yet genomic studies in mice have lagged behind those in humans.

4 Jul 2016

Study shows how genetic variants control immune cell response to pathogens

A study that is first in its kind and published in Nature Medicine today has looked at how far genetic factors control the immune cell response to pathogens in healthy individuals.

4 Jul 2016

Recommendations for integrating genomic results into clinical practice

A quiet transformation has been brewing in medicine, as large-scale DNA results become increasingly available to patients and healthcare providers.

1 Jul 2016

Kataegis linked to better prognosis for breast cancer patients

Kataegis is a recently discovered phenomenon in which multiple mutations cluster in a few hotspots in a genome. The anomaly was previously found in some cancers, but it has been unclear what role kataegis plays in tumor development and patient outcomes.

1 Jul 2016

Study focuses on critical proteins involved in ovarian cancer biology

In what is believed to be the largest study of its kind, scientists at the Pacific Northwest National Laboratory, Johns Hopkins University and their collaborators from institutions across the nation have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors.

30 Jun 2016

Genomic News and Research

Scientists identify timing of major metabolic shift in developing neurons

International project to develop globally accessible bank of new cancer cell models for research

Gut bacteria can help predict susceptibility to rheumatoid arthritis

Researchers receive $9 million grant to develop novel platform to quickly identify new antibiotics

JAX researchers find precise, reliable way to identify leukemia cells of origin

NIH selects VUMC to play foundational role in PMI Cohort Program

Five-year NIH grant awarded to four NYC medical centers for PMI Cohort Program

Molecule thought to indicate good cancer prognosis can have dark side, research shows

Scientists identify set of genes that could predict clinical outcomes in patients with FLT3-ITD AML

Germline genetic testing necessary for men with metastatic prostate cancer

Researchers discover mechanism of gene silencing in hormone-dependent breast cancer cells

TSRI awarded $20 million for first year of precision medicine initiative cohort program

New study to investigate how genetic factors contribute to breast cancer disparities

Whole-genome omics data can improve accuracy of breast cancer survival predictions

LouLou Foundation, ODC announce 11 new grants for research on CDKL5 deficiency

Novel technique could help discover genes linked to complex traits in any animal model

Study shows how genetic variants control immune cell response to pathogens

Recommendations for integrating genomic results into clinical practice

Kataegis linked to better prognosis for breast cancer patients

Study focuses on critical proteins involved in ovarian cancer biology

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News