Genomic News and Research

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Scientists develop largest ever series of human breasts cancers grafted into mice

At the Institut Curie, Inserm researchers and physicians have established the largest ever panel of human breast cancer xenografts in animal models.

13 Jul 2007

Sigma-Aldrich launches Imprint DNA Modification kit

Sigma-Aldrich has announced the launch of the Imprint DNA Modification kit.

11 Jul 2007

Discovery of enzyme critical in DNA replication

In this week's issue of Science, researchers from the National Institute of Environmental Health Sciences (NIEHS) and Umea University in Sweden report an important discovery about a critical new role that an enzyme called DNA polymerase epsilon plays in replicating DNA in higher organisms such as yeast and perhaps even humans.

9 Jul 2007

RNA molecules can orchestrate gene activity across vast portions of the human genome

Large, seemingly useless pieces of RNA - a molecule originally considered only a lowly messenger for DNA - play an important role in letting cells know where they are in the body and what they are supposed to become, researchers at Stanford University School of Medicine have discovered.

29 Jun 2007

Many of the areas of the human genome previously thought to be deserts are in fact teeming with life

Most known human genes in the genome map are still incompletely annotated, says Professor Alexandre Reymond, from the Centre for Integrative Genomics, University of Lausanne, Switzerland and the Department of Genetic Medicine, University of Geneva, Geneva, Switzerland.

19 Jun 2007

True nature of heterochromatin revealed

Not so long ago, the difficult-to-sequence, highly repetitive, gene-poor DNA found in regions of chromosomes known as heterochromatin was called "junk." Like dark matter in the universe, the true nature of heterochromatin was unknown.

19 Jun 2007

Researchers use 'genomic pathway' to predict Parkinson's

A new Mayo Clinic study provides strong evidence that the joint effects of common DNA variations in several genes that encode proteins within a well-defined biological pathway largely explain why some persons get Parkinson's disease while others don't, and even predict with great accuracy at what age people might develop their first symptoms.

17 Jun 2007

Discovery of IKBKE gene linked to breast cancer

Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers.

17 Jun 2007

The unexpected connection of two gene regulation mechanisms points to new ways for the fight against leukemia

When the activity of individual genes it is longer required, there are two main mechanisms responsible for the “switching off”, mainly DNA methylation and the Polycomb protein complex. Sometimes, these mechanisms lose their efficiency and some of the genes that should be "switched off" remain active.

16 Jun 2007

Sensitivity to diverse range of chemotherapeutic drugs linked to common pathway

Using a functional genomic screen, scientists have defined elements that impact the responsiveness of cancer cells to drugs commonly used as anticancer therapeutics.

15 Jun 2007

Physiological differences between men and women impact colorectal cancer progression

Physiological differences between men and women may contribute to differential tumor development and progression in colon cancer patients, a study led by researchers at the University of Southern California (USC) suggests.

5 Jun 2007

New protocols to understand embryos, clones, stem cells

Cloning, X-chromosome inactivation, stem cells, and embryogenesis are hot areas of research at the moment, and protocols featured in this month's release of Cold Spring Harbor Protocols will aid these studies.

3 Jun 2007

Virus widely used in gene therapy research yields important clues to genomic instability

Genomic instability, the rearrangement of chromosomes or an abnormal number of chromosomes, is a hallmark of many human cancers.

1 Jun 2007

Complete sequencing of DNA pioneer James D. Watson

454 Life Sciences Corporation, in collaboration with scientists at the Human Genome Sequencing Center, Baylor College of Medicine, announced in Houston, Texas, the completion of a project to sequence the genome of James D. Watson, Ph.D., co-discoverer of the double-helix structure of DNA.

1 Jun 2007

Pharmacists play critical role in reducing medication discrepancies

Involving pharmacists in obtaining and assessing a patient's medication history before elective surgery can significantly reduce medication discrepancies upon hospital admission.

30 May 2007

Scientists develop a more human-like mouse model of cancer

A team led by Dana-Farber Cancer Institute scientists has developed a more human-like mouse model of cancer they say will aid the search for cancer-causing genes and improve the predictive value of laboratory drug testing.

28 May 2007

Tool will revolutionise functional genomic studies in clostridia

The genome of the organism that produces the world's most lethal toxin has been revealed.

24 May 2007

Peering into the body and visualizing its molecular secrets one step closer to reality

Peering into the body and visualizing its molecular secrets, once the stuff of science fiction, is one step closer to reality with a study from researchers at the Stanford University School of Medicine and the University of California, San Diego School of Medicine.

22 May 2007

In some species estrogen plays a key role in aggressiveness

Imagine if a naturally occurring chemical in your body could help make you feel more calm and relaxed ? but it would only work during the long days of summer.

22 May 2007

Decoding gene expression in cancer tumors using noninvasive imaging

By correlating images of cancerous liver tissue with gene expression patterns, a research team led by a radiologist at the University of California, San Diego (UCSD) School of Medicine has developed tools that may some day allow physicians to view a CT image of a cancer tumor and discern its genetic activity.

22 May 2007

Genomic News and Research

Scientists develop largest ever series of human breasts cancers grafted into mice

Sigma-Aldrich launches Imprint DNA Modification kit

Discovery of enzyme critical in DNA replication

RNA molecules can orchestrate gene activity across vast portions of the human genome

Many of the areas of the human genome previously thought to be deserts are in fact teeming with life

True nature of heterochromatin revealed

Researchers use 'genomic pathway' to predict Parkinson's

Discovery of IKBKE gene linked to breast cancer

The unexpected connection of two gene regulation mechanisms points to new ways for the fight against leukemia

Sensitivity to diverse range of chemotherapeutic drugs linked to common pathway

Physiological differences between men and women impact colorectal cancer progression

New protocols to understand embryos, clones, stem cells

Virus widely used in gene therapy research yields important clues to genomic instability

Complete sequencing of DNA pioneer James D. Watson

Pharmacists play critical role in reducing medication discrepancies

Scientists develop a more human-like mouse model of cancer

Tool will revolutionise functional genomic studies in clostridia

Peering into the body and visualizing its molecular secrets one step closer to reality

In some species estrogen plays a key role in aggressiveness

Decoding gene expression in cancer tumors using noninvasive imaging

Genetics & Genomics - Second Edition eBook

Michael Stryker

The past, present and future of automation and digitalization in the life sciences laboratory

Arxspan BioDrive: A Versatile Solution for Molecular Biology

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