Genomic Sequencing News and Research

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Tgen And Baylor secure federal grant to develop early detection system for pancreatic cancer

A group of the nation's premier cancer researchers led by the Baylor Scott & White Research Institute and the Translational Genomics Research Institute -- has secured a $5.13 million federal grant to develop an early detection system for pancreatic cancer, the nation's third-leading cause of cancer-related death.

11 Dec 2017

DNA sequencing could identify genetic cause of kidney disease

DNA sequencing could soon become part of the routine diagnostic workup for patients with chronic kidney disease, suggests a new study from Columbia University Medical Center.

5 Dec 2017

Pioneering research to grow mini bowel cancer tumor models in the lab

Charity Cancer Research UK has awarded the University of Birmingham £1.5 million to fund a five-year research program aimed at finding new treatments for bowel cancer.

6 Nov 2017

University of Birmingham researchers receive £1.5 million to find new treatments for bowel cancer

Charity Cancer Research UK has awarded the University of Birmingham £1.5 million to fund a five-year research program aimed at finding new treatments for bowel cancer.

2 Nov 2017

Genome-wide molecular tests can guide treatment in recurrent glioblastoma, study shows

Several patients with recurring glioblastoma, a deadly brain cancer, survived for more than a year in a clinical trial believed to be the first to use comprehensive DNA and RNA sequencing of a patient's tumor to inform treatment for these patients in real-time.

27 Oct 2017

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Some scientists have suspected that the most common form of ovarian cancer may originate in the fallopian tubes, the thin fibrous tunnels that connect the ovaries to the uterus.

24 Oct 2017

Existing drugs could help patients with rare form of bone cancer

Patients with a rare bone cancer of the skull and spine - chordoma - could be helped by existing drugs, suggest scientists from the Wellcome Trust Sanger Institute, University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust.

12 Oct 2017

Five new ways individualized medicine has moved from research lab into clinical care

Advancements in individualized medicine are offering health care providers new tools to quickly and accurately diagnose, treat, predict and, eventually, prevent disease. Keith Stewart, M.B., Ch.B., Carlson and Nelson Endowed Director, Mayo Clinic Center for Individualized Medicine, today outlined five new ways individualized medicine has moved from the research lab into clinical care. Dr. Stewart made his statements during the opening of the 2017 "Individualizing Medicine Conference: Advancing Care Through Genomics" in Rochester.

9 Oct 2017

Alterations in circulating tumor DNA associated with response to checkpoint inhibitors

The number of alterations detected in the DNA collected from blood samples (liquid biopsies) of cancer patients treated with immune checkpoint inhibitors was associated with response to the treatment.

3 Oct 2017

Combined DNA and protein 'liquid biopsy' more accurate in identifying early-stage pancreatic cancer

Johns Hopkins scientists say they have developed a blood test that spots tumor-specific DNA and protein biomarkers for early-stage pancreatic cancer.

4 Sep 2017

Novel blood test identifies tumor-derived DNA in early-stage cancer patients

In a bid to detect cancers early and in a noninvasive way, scientists at the Johns Hopkins Kimmel Cancer Center report they have developed a test that spots tiny amounts of cancer-specific DNA in blood and have used it to accurately identify more than half of 138 people with relatively early-stage colorectal, breast, lung and ovarian cancers.

17 Aug 2017

Researchers develop new technique to locate pathogenic mutations in dark, non-coding genome

When doctors can't find a diagnosis for patient's disease, they turn to genetic detectives. Equipped with genomic sequencing technologies available for less than 10 years, these sleuths now routinely search through a patient's DNA looking for mutations responsible for mysterious diseases.

11 Aug 2017

In-depth tumor sequencing reveals key molecular drivers of metastatic cancers

Five hundred cancer patients are getting an in-depth look at their genomes as part of a new clinical study that is revealing some of the key molecular drivers of metastatic cancers.

3 Aug 2017

Physiology-driven genetic changes have positive influence on brain development

SCIENTISTS in the UK and India have discovered more evidence that positive stimuli in early childhood can benefit the infant brain.

31 Jul 2017

NETRF announces new research grants to advance treatments for neuroendocrine tumors

The Neuroendocrine Tumor Research Foundation has announced a new round of scientific and clinical research grants, aimed at advancing the treatment of and the search for cures to neuroendocrine tumors.

21 Jul 2017

New genomic research partnership promises to redefine and transform cancer treatment

Personalized cancer therapies are on the horizon thanks to a new genomic cancer research partnership between the Gene Editing Institute of Christiana Care Health System's Helen F. Graham Cancer Center & Research Institute and the biotechnology company NovellusDx.

21 Jul 2017

First systematic genomic analysis of patients with T-ALL may aid development of new therapies

A consortium including St. Jude Children's Research Hospital and the Children's Oncology Group has performed an unprecedented genomic sequencing analysis of hundreds of patients with T-lineage acute lymphoblastic leukemia (T-ALL).

4 Jul 2017

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

A subgroup of patients with osteosarcoma - a form of bone cancer - could be helped by an existing drug, suggest scientists from the Wellcome Trust Sanger Institute and their collaborators at University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust.

23 Jun 2017

Study provides new insight into cells that rejuvenate the brain

Alzheimer's disease is a neurodegenerative disease manifested by various neuronal pathological processes and a significant decline in brain function.

9 Jun 2017

New genomic sequencing approach could be first step toward blood tests for early cancer detection

In a study of 124 patients with advanced breast, lung, and prostate cancers, a new, high-intensity genomic sequencing approach detected circulating tumor DNA at a high rate.

5 Jun 2017