Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

New report explains occurrence of breast cancer in women with normal BRCA genes

Since 1994, many thousands of women with breast cancer from families severely affected with the disease have been tested for inherited mutations in BRCA1 and BRCA2. The vast majority of those patients were told that their gene sequences were normal.

25 Oct 2013

Unique approach to help discover how cell changes shape in response to topographies

Cells in the human body change shape as they crawl, split, or cling to other surfaces, but while the scientific literature is filled with examples of how cell shapes shift in response to things they touch, little is known about the rules that govern these changes. And there has been no high-throughput way to systematically test different topologies against different types of cells to optimize the surface of something like a medical implant.

24 Oct 2013

Study uncovers new genetic pathways that could revolutionise acute dendritic leukaemia treatment

Acute dendritic leukaemia is a rare type of leukaemia, but one with the worst prognosis-the average patient survival rate is just 12-14 months-that is difficult to treat. Juan Cruz Cigudosa's team, from the Spanish National Cancer Research Centre's Molecular Cytogenetics Group, has for the first time sequenced the exome -the coding, or protein-generating, regions of the genome- of dendritic cell leukaemia.

24 Oct 2013

Startup Wins Five-Year Exclusive License To Decode Genetics Platform

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23 Oct 2013

Inflammation causally linked to functional decline in aging

Inflammation is the common denominator of many chronic age-related diseases such as arthritis, gout, Alzheimer's, and diabetes. But according to a Yale School of Medicine study, even in the absence of a disease, inflammation can lead to serious loss of function throughout the body, reducing healthspan - that portion of our lives spent relatively free of serious illness and disability.

23 Oct 2013

STSI receives $29M grant to support innovative research on genomics, wireless technology and bioinformatics

The National Institutes of Health has renewed its prestigious Clinical and Translational Science Award (CTSA) with the Scripps Translational Science Institute (STSI) in the amount of $29 million over the next five years to support innovative research in genomics, wireless technology and bioinformatics toward individualizing medicine.

23 Oct 2013

Illumina announces launch of TruGenome Undiagnosed Disease Test

Illumina, Inc. today announced the launch of its TruGenome Undiagnosed Disease Test provided by the CLIA-certified, CAP-accredited Illumina Clinical Services Laboratory.

From Illumina, Inc. 22 Oct 2013

Buck Institute finds link between ApoE4 and anti-aging protein targeted by resveratrol in red wine

he major genetic risk factor for Alzheimer's disease (AD), present in about two-thirds of people who develop the disease, is ApoE4, the cholesterol-carrying protein that about a quarter of us are born with. But one of the unsolved mysteries of AD is how ApoE4 causes the risk for the incurable, neurodegenerative disease.

22 Oct 2013

U.K. Organizations Partner With Illumina To Sequence 10,000 Whole Genomes

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From Illumina, Inc. 21 Oct 2013

Claritas Partners With Life Tech, Lockheed To Sequence Military Veteran Exomes

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21 Oct 2013

New collaborative project aims to discover genes underlying rare genetic diseases

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21 Oct 2013

Bioengineers build novel tool to visualize protein networks from breast cancer cell data

A colorful wheel developed by Rice University bioengineers to visualize protein interactions has won an international competition for novel strategies to study the roots of breast cancer.

21 Oct 2013

New small-molecule inhibitor shows promising results in drug-resistant melanoma, breast cancer

LEE011, a small-molecule inhibitor of cyclin-dependent kinases (CDK) 4/6 being developed by Novartis Oncology, showed promising results in drug-resistant melanoma and drug-resistant breast cancer when tested in combination with other targeted therapies, and based on these preclinical results, several phase I clinical trials were launched recently, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held October 19-23.

21 Oct 2013

Research: Zebrafish exhibits same developmental issues as humans

Duke researchers have connected very rare and precise duplications and deletions in the human genome to their complex disease consequences by duplicating them in zebrafish.

18 Oct 2013

New England publishes results of phase III clinical trial of ABRAXANE for metastatic pancreatic cancer

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation , today announced the results of the MPACT phase III clinical trial of ABRAXANE® in combination with gemcitabine were published online in the October 16th edition of the New England Journal of Medicine.

17 Oct 2013

Imaxio Sells Genomics Division To Hybrigenics

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16 Oct 2013

Study aims to identify age-related changes in metabolic pathways

Have you ever wondered why young children can eat bags of Halloween candy and feel fine the next day - compared to adults who experience all sorts of agony following the same junk food binge? Evolution and a gene called Foxo may be to blame. Working in fruit flies, scientists at the Buck Institute have identified a mechanism that helps the flies adapt to changes in diet when they're young; they've discovered that same mechanism gets misregulated as the flies age, disrupting metabolic homeostasis, or balance.

16 Oct 2013

Key marker in blood and urine identifies genetic mutations in gene responsible for RP

Research led by physician-scientists at Bascom Palmer Eye Institute of the University of Miami Miller School of Medicine has produced a breakthrough discovery in diagnosing retinitis pigmentosa, a blinding disease that affects about 1 in 4,000 people in the United States.

16 Oct 2013

Researchers make breakthrough discovery in diagnosing retinitis pigmentosa

15 Oct 2013

CNIO researchers perform first exome sequencing for non-infiltrating bladder cancer

Bladder cancer represents a serious public health problem in many countries, especially in Spain, where 11,200 new cases are recorded every year, one of the highest rates in the world. The majority of these tumours have a good prognosis -- 70-80% five-year survival after diagnosis -- and they do not infiltrate the bladder muscle at the time of diagnosis -- in around 80% of cases.

14 Oct 2013

Genomics News and Research

Further Reading

New report explains occurrence of breast cancer in women with normal BRCA genes

Unique approach to help discover how cell changes shape in response to topographies

Study uncovers new genetic pathways that could revolutionise acute dendritic leukaemia treatment

Startup Wins Five-Year Exclusive License To Decode Genetics Platform

Inflammation causally linked to functional decline in aging

STSI receives $29M grant to support innovative research on genomics, wireless technology and bioinformatics

Illumina announces launch of TruGenome Undiagnosed Disease Test

Buck Institute finds link between ApoE4 and anti-aging protein targeted by resveratrol in red wine

U.K. Organizations Partner With Illumina To Sequence 10,000 Whole Genomes

Claritas Partners With Life Tech, Lockheed To Sequence Military Veteran Exomes

New collaborative project aims to discover genes underlying rare genetic diseases

Bioengineers build novel tool to visualize protein networks from breast cancer cell data

New small-molecule inhibitor shows promising results in drug-resistant melanoma, breast cancer

Research: Zebrafish exhibits same developmental issues as humans

New England publishes results of phase III clinical trial of ABRAXANE for metastatic pancreatic cancer

Imaxio Sells Genomics Division To Hybrigenics

Study aims to identify age-related changes in metabolic pathways

Key marker in blood and urine identifies genetic mutations in gene responsible for RP

Researchers make breakthrough discovery in diagnosing retinitis pigmentosa

CNIO researchers perform first exome sequencing for non-infiltrating bladder cancer

Omics eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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