Genomics News and Research

RSS

Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

Children born with CDG don't contain mutation in every cell type, say Sanford-Burnham researchers

Children born with rare, inherited conditions known as Congenital Disorders of Glycosylation, or CDG, have mutations in one of the many enzymes the body uses to decorate its proteins and cells with sugars.

10 May 2013

Researchers reveal how genes are turned on and off during early human development

A large, multi-institutional research team involved in the NIH Epigenome Roadmap Project has published a sweeping analysis in the current issue of the journal Cell of how genes are turned on and off to direct early human development.

10 May 2013

USF, Aetna to examine influence of genetic testing on breast cancer treatment

The University of South Florida and Aetna are launching a ground-breaking study that will examine the influence genetic testing may have on clinical treatment decisions among breast cancer patients and their doctors.

10 May 2013

UA researchers discover genetic mutations that cause severe epilepsies in children

Researchers at the University of Arizona have successfully determined the genetic mutations causing severe epilepsies in seven out of 10 children for whom the cause of the disorder could not be determined clinically or by conventional genetic testing.

9 May 2013

Researchers identify genetic mutations that appear to underlie rare syndrome

Researchers from Massachusetts General Hospital and Duke University have identified genetic mutations that appear to underlie a rare but devastating syndrome combining reproductive failure with cerebellar ataxia - a lack of muscle coordination - and dementia.

9 May 2013

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Kinase inhibitors are molecules that block the activity of kinases. Kinases are a specific class of enzymes. They are extremely important in signal transduction processes in the human body meaning that they actually regulate most of the physiological processes that take place in the body.

7 May 2013

Study brings opportunities of personalised therapy for breast cancer a step closer

A study led by prominent breast cancer experts from Europe and the US has revealed a number of potentially important prospects for targeted therapies, and brings opportunities of truly personalised therapy for breast cancer a step closer, researchers said at the 5th IMPAKT Breast Cancer Conference in Brussels, Belgium.

2 May 2013

Genomics-based testing could change recommended course of treatment for endometrial cancer

The most in-depth look yet at endometrial cancer shows that adding genomics-based testing to the standard diagnostic workup could change the recommended course of treatment for some women.

2 May 2013

Research findings pave the way for developing better treatments for AML

A team of researchers led by Washington University School of Medicine in St. Louis has identified virtually all of the major mutations that drive acute myeloid leukemia, a fast-growing blood cancer in adults that often is difficult to treat.

2 May 2013

Findings set the stage for identifying potential new drug targets, treatment strategies for AML

nvestigators for The Cancer Genome Atlas Research Network have detailed and broadly classified the genomic alterations that frequently underlie the development of acute myeloid leukemia, a deadly cancer of the blood and bone marrow.

2 May 2013

Details about genomic landscapes of AML and endometrial cancer revealed

Two studies from The Cancer Genome Atlas program reveal details about the genomic landscapes of acute myeloid leukemia and endometrial cancer.

2 May 2013

PTSD study: Individuals with childhood abuse history have distinct changes in gene activity patterns

Abuse during childhood is different. A study of adult civilians with PTSD (post-traumatic stress disorder) has shown that individuals with a history of childhood abuse have distinct, profound changes in gene activity patterns, compared to adults with PTSD but without a history of child abuse.

2 May 2013

New methods boost researchers' analytical powers by incorporating prior knowledge about SNPs function

As scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly threatened by the unthinkable: Too much data to make full sense of.

26 Apr 2013

Network of genes is a crucial mechanism driving Late Onset Alzheimer's Disease

Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in the inflammatory response in the brain is a crucial mechanism driving Late Onset Alzheimer's Disease (LOAD).

26 Apr 2013

Geisinger and Bucknell celebrates opening of Autism and Developmental Medicine Center

Officials from Geisinger Health System and Bucknell University celebrated the grand opening of the Autism and Developmental Medicine Center, a national model for implementing guidelines for early diagnosis, medication management and treatment options for children with developmental disorders.

26 Apr 2013

Mayo Clinic implements electronic warning system to identify patients at risk of QT-related deaths

Using a one-of-a-kind computer-aided program, Mayo Clinic has developed and implemented a Mayo-wide electronic warning system to identify patients at risk of QT-related deaths from an abnormality in the heart's electrical system.

26 Apr 2013

Mechanism of tumor suppressor p53 inactivation described

Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don’t belong. One protein that keeps healthy cells from behaving this way is a tumor suppressor named p53. This protein stops potentially precancerous cells from dividing and induces suicide in those that are damaged beyond repair. Not surprisingly, p53’s critical function is disrupted in most cancers.

25 Apr 2013

Genomics News and Research

Further Reading

Children born with CDG don't contain mutation in every cell type, say Sanford-Burnham researchers

Researchers reveal how genes are turned on and off during early human development

USF, Aetna to examine influence of genetic testing on breast cancer treatment

UA researchers discover genetic mutations that cause severe epilepsies in children

Researchers identify genetic mutations that appear to underlie rare syndrome

Kinase inhibitors: an interview with Jan Hoflack, CSO of Oncodesign

Study brings opportunities of personalised therapy for breast cancer a step closer

Genomics-based testing could change recommended course of treatment for endometrial cancer

Research findings pave the way for developing better treatments for AML

Findings set the stage for identifying potential new drug targets, treatment strategies for AML

Details about genomic landscapes of AML and endometrial cancer revealed

PTSD study: Individuals with childhood abuse history have distinct changes in gene activity patterns

New methods boost researchers' analytical powers by incorporating prior knowledge about SNPs function

Network of genes is a crucial mechanism driving Late Onset Alzheimer's Disease

Geisinger and Bucknell celebrates opening of Autism and Developmental Medicine Center

Mayo Clinic implements electronic warning system to identify patients at risk of QT-related deaths

Mechanism of tumor suppressor p53 inactivation described

Thought Leaders Consortium discusses new vision for medicine in healthcare

Hospital for Special Surgery receives grant for new genomics center to study autoimmune diseases

Cultivation of legumes helps farmers add natural nitrogen to agricultural fields

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest Life Science News