Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

Genomics in China

Ten years ago, the Chinese National Human Genome Center at Shanghai (South Center, hereafter) was established in the Zhangjiang HiTech Park of Pudong District in Shanghai.

7 Jan 2009

Gene mutations found to predict acute lymphoblastic leukemia relapse

Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL).

7 Jan 2009

Metadherin gene linked to metastasis of breast cancer

A team of researchers at Princeton University and The Cancer Institute of New Jersey has identified a long-sought gene that is fatefully switched on in 30 to 40 percent of all breast cancer patients, spreading the disease, resisting traditional chemotherapies and eventually leading to death.

5 Jan 2009

New understanding of genetic signature associated with Alzheimer's disease

Scientists have new information about the complex genetic signature associated with Alzheimer's disease, the leading cause of cognitive decline and dementia in the elderly.

1 Jan 2009

Few DNA repair gene variants associated with increased cancer risk

Variants of numerous DNA repair genes initially appeared to be statistically significantly associated with cancer risk in epidemiological studies.

1 Jan 2009

Cellular reprogramming, the 'Breakthrough of the Year' according to AAAS

In its annual list of the year's top ten scientific breakthroughs, the journal Science has given top honors to research that produced "made-to-order" cell lines by reprogramming cells from ill patients.

18 Dec 2008

11 new genes linked to LDL, HDL cholesterols and triglycerides

A new study uncovers 11 gene variants associated with three blood lipids measured to determine cardiovascular disease risk: low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) and triglycerides.

15 Dec 2008

Discovery of seven new sites in the human genome found to influence obesity

In one of the largest studies of its kind, a multinational team led by scientists from deCODE genetics has reported the discovery of common variations at seven new sites in the human genome found to influence obesity.

14 Dec 2008

Entomologists look for Lyme disease answers in tick saliva

In research that could mitigate the spread of Lyme disease, Kansas State University entomologists are looking for answers in tick saliva.

12 Dec 2008

Computation and genomics data drive bacterial research into new golden age

A potent combination of powerful new analysis methods and abundant data from genomics projects is carrying microbiology forward into a new era.

10 Dec 2008

New vaccine theory aimed at ticks and mosquitoes to prevent disease transmission

Most successful vaccines and drugs rely on protecting humans or animals by blocking certain bacteria from growing in their systems.

3 Dec 2008

Discovery of a presbycusis related gene

Presbycusis, or age-related hearing loss, accounts for 30 percent of all hearing loss. So, why do some people lose their hearing as they get older but other people can still hear a pin drop?

3 Dec 2008

Large study looks at genetic risks for schizophrenia and bipolar disorder

A multi-institution team of investigators led by researchers at the Keck School of Medicine of the University of Southern California (USC) has received $19 million in funding from the National Institutes of Mental Health (NIMH) for a groundbreaking effort to collect genetic information on tens of thousands of patients in order to study the genetic risks for schizophrenia and bipolar disorder.

3 Dec 2008

Multitasking proteins driving cell behavior

A study describing how cells within blood vessel walls move en masse overturns an assumption common in the age of genomics - that the proteins driving cell behavior are doing so much multitasking that it would be near impossible to group them according to a few discrete functions.

30 Nov 2008

Genomics and bioinformatics could be the future in battle against malaria

Malaria, one of the oldest diseases known to man, has shown no signs of slowing down as it ages.

26 Nov 2008

Impending crisis in provision of histopathology expertise for mouse functional genomics

The generation of new mouse models of human disease is accelerating rapidly due to the completion of whole-genome sequencing efforts and technological advances in the manipulation of the mouse genome.

18 Nov 2008

Gene chip technology used to rapidly and accurately detect pneumonia in ICU Patients on ventilators

Even seasoned doctors have a difficult time diagnosing pneumonia in hospitalized patients breathing with the assistance of a ventilator.

16 Nov 2008

Breakthrough in cellular analysis

Like skilled assassins, many diseases seem to know exactly what types of cells to attack.

16 Nov 2008

Breakthrough in cell-type analysis offers new ways to study development and disease

Like skilled assassins, many diseases seem to know exactly what types of cells to attack. While decimating one cadre of cells, diseases will inexplicably spare a seemingly identical group of neighbors. What makes cells vulnerable or not depends largely on the kinds and amounts of proteins they produce - their 'translational profile,' in the lingo of molecular biology. For this reason, scientists have struggled to parse the subtle molecular differences among the hundreds of specialized cell types that are tangled together in tissues like the brain.

13 Nov 2008