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Parkinson's disease drug ropinirole is safe and tolerable for ALS patients, early clinical trial shows

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles.

1 Jun 2023

Targeting mucus plugs could help prevent deaths from COPD, study suggests

A retrospective analysis of patient data from the COPDGene study suggests that targeting mucus plugs could help prevent deaths from chronic obstructive pulmonary disease-;the fourth leading cause of death in the United States.

22 May 2023

Study pinpoints how gut microbes boost the body's response to cancer immunotherapy

Cancer immunotherapy has transformed the treatment of many types of cancer. Yet, for reasons that remain poorly understood, not all patients get the same benefit from these powerful therapies.

4 May 2023

Many melanoma patients could avoid the risk for toxicity from combination therapies, study suggests

Data from a national clinical trial shows that a striking 89% of patients with desmoplastic melanoma responded to immunotherapy (pembrolizumab) alone, suggesting that many patients could avoid the risk for toxicity from combination therapies and achieve cancer control with this approach to treatment.

17 Apr 2023

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

The number of immune cells in and around kidney tumors, the amount of dead cancer tissue, and mutations to a tumor suppressor gene called PBRM1 form a biomarker signature that can predict — before treatment begins — how well patients with kidney cancer will respond to immunotherapy, according to new research directed by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Study reveals potential for digital technology to improve patients' asthma control

A new international study led by RCSI University of Medicine and Health Sciences has revealed significant potential for digital technology to improve asthma control for patients.

6 Apr 2023

Penn researchers discover new type of cell that may play key role in human lung diseases

A new type of cell that resides deep within human lungs and may play a key role in human lung diseases has been discovered by researchers at the Perelman School of Medicine at the University of Pennsylvania.

3 Apr 2023

AAN selects UC San Francisco neurologist to receive 2023 Dreifuss-Penry Epilepsy Award

Jon Kleen, MD, PhD, UC San Francisco neurologist, epileptologist and neuroscientist, has been chosen by the American Academy of Neurology to receive its 2023 Dreifuss-Penry Epilepsy Award. He is being honored for his outstanding contributions in clinical research and leadership in the treatment of epilepsy.

21 Mar 2023

Confronting anti-vaccine activism by disseminating accurate narratives on life-saving benefits of vaccines

Public and private sector health officials and public policymakers should team up immediately with community leaders to more effectively disseminate accurate narratives regarding the life-saving benefits of vaccines to counter widespread, harmful misinformation from anti-vaccine activists.

3 Mar 2023

Social and economic disadvantage may explain the higher risk of dementia in women

A large international study of dementia risk involving almost 30,000 people from 18 countries covering all six continents suggests that social and economic disadvantage may explain the higher risk of the condition in women.

15 Feb 2023

New screening tool shows promise to help primary care physicians identify COPD

Researchers at National Jewish Health and colleagues across the country have partnered to develop a screening tool to help primary care physicians identify chronic obstructive pulmonary disease (COPD).

14 Feb 2023

Multi-country study examines clinical and community antibiotic use during the pandemic

Globally, during the first two years of the COVID-19 pandemic, antibiotics were prescribed to 75 percent of COVID-19 patients despite bacterial coinfection rates averaging less than 10 percent.

6 Feb 2023

Researchers discover mechanism underlying the development and intensification of cancer treatment-related pain

A combination of chemotherapy and drugs that stimulate the immune system to combat cancer is increasingly used to control progression of the disease in patients.

30 Jan 2023

Newly revised classification tool for standardized diagnostic reporting of melanocytic lesions

With the growing number of skin biopsies performed annually for suspected melanoma, a simple, easily understood standardized classification system for melanocytic lesions is increasingly important to aid pathologists and clinicians who examine millions of tissue samples each year and to alleviate patient confusion and anxiety.

11 Jan 2023

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Patients with localized, hormone receptor-positive, HER2-low breast cancer treated with trastuzumab deruxtecan (T-DXd, Enhertu) in the neoadjuvant setting had an overall response rate of 75 percent in the absence of anastrozole and 63 percent in combination with anastrozole, according to results from the phase II TRIO-US B-12 TALENT trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

Shingles linked with higher long-term risk of major cardiovascular event

A new study by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, demonstrated that shingles, also known as herpes zoster, is associated with an almost 30% higher long-term risk of a major cardiovascular event such a stroke or heart attack.

22 Nov 2022

Cancer Research Horizons: The Innovation Engine of Cancer Research UK

Following ELRIG 2022, News-Medical speaks with Cancer Research Horizons, the innovation engine of Cancer Research UK about their efforts to advance the drug discovery sector.

From Cancer Research UK 14 Nov 2022

New program leverages digital solutions to improve patients' blood pressure and cholesterol levels

Heart disease is the leading cause of death in the United States and around the world. Lowering high blood pressure and cholesterol could help to reduce morbidity and mortality, but frequent in-person visits to measure and manage these readouts can be a burden for patients.

9 Nov 2022

Study finds new drug combination to be more effective against complicated urinary tract infections

An international study led by a Rutgers scientist comparing new and older treatments against complicated urinary tract infections has found a new drug combination to be more effective, especially against stubborn, drug-resistant infections.

25 Oct 2022

Researchers discover how cancer cells can turn off the immune system to help tumors grow

When cancer arises in the body, it starts with tumor cells that rapidly grow and divide and eventually spread.

29 Sep 2022