Glioblastoma News and Research

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Glioblastoma is the most aggressive and malignant form of glioma, a type of primary brain cancer. Surgery is often used to treat gliomas, along with radiation. However, since surgery and radiation fail to cure the disease, doctors may turn to additional radiation or chemotherapy. In early stages glioblastoma tumors often grow without symptoms and therefore can become quite large before symptoms arise. When the tumor becomes symptomatic, tumor growth is usually very rapid and is accompanied by altered brain function, and if left untreated the disease becomes lethal. Although primary treatment is often successful in temporarily stopping the progression of the tumor, glioblastomas almost always recur and become lethal.
Folic acid-like drug reprograms DNA methylome of aggressive brain tumors

Folic acid-like drug reprograms DNA methylome of aggressive brain tumors

Inhaled CBD shrinks glioblastoma’s size in an animal model

Inhaled CBD shrinks glioblastoma’s size in an animal model

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

Clinical drug research for the treatment of CNS and neurological disorders

Clinical drug research for the treatment of CNS and neurological disorders

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

Novel protein regulator of tumor angiogenesis may be a therapeutic target for difficult-to-treat cancers

Novel protein regulator of tumor angiogenesis may be a therapeutic target for difficult-to-treat cancers

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

Study reveals a link between neuroinflammation protein and survival outcomes in glioblastoma patients

Study reveals a link between neuroinflammation protein and survival outcomes in glioblastoma patients

Wyss Center to lead a collaborative project aimed at improving brain cancer treatment

Wyss Center to lead a collaborative project aimed at improving brain cancer treatment

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Northwestern’s SPORE has made advances in understanding the genetic basis of glioblastoma

Northwestern’s SPORE has made advances in understanding the genetic basis of glioblastoma

Advanced technique offers new insights about the dynamics of gliomas

Advanced technique offers new insights about the dynamics of gliomas

Long-held theory of cancer-induced immune suppression requires revision, study says

Long-held theory of cancer-induced immune suppression requires revision, study says

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Small molecule drug can attenuate the triggers of neuroinflammation, preclinical study shows

Sex, age are crucial factors in the care and survival of patients with malignant brain tumors

Sex, age are crucial factors in the care and survival of patients with malignant brain tumors

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Novel cell reprogramming offers a promising therapeutic strategy to slow down glioblastomas

Results from Phase 0/1 trial of ribociclib plus everolimus in patients with high-grade glioma announced

Results from Phase 0/1 trial of ribociclib plus everolimus in patients with high-grade glioma announced

Targeting and inhibiting a protein could provide more effective treatment for brain cancer

Targeting and inhibiting a protein could provide more effective treatment for brain cancer

DNMT2/TRDMT1 gene knockout may potentiate adverse effects related to drug-induced senescence

DNMT2/TRDMT1 gene knockout may potentiate adverse effects related to drug-induced senescence

Study assesses contemporary burden of brain and other CNS tumors in the U.S

Study assesses contemporary burden of brain and other CNS tumors in the U.S