Glioblastoma News and Research

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Glioblastoma is the most aggressive and malignant form of glioma, a type of primary brain cancer. Surgery is often used to treat gliomas, along with radiation. However, since surgery and radiation fail to cure the disease, doctors may turn to additional radiation or chemotherapy. In early stages glioblastoma tumors often grow without symptoms and therefore can become quite large before symptoms arise. When the tumor becomes symptomatic, tumor growth is usually very rapid and is accompanied by altered brain function, and if left untreated the disease becomes lethal. Although primary treatment is often successful in temporarily stopping the progression of the tumor, glioblastomas almost always recur and become lethal.
New cellular pathway limits growth and spread of brain tumors

New cellular pathway limits growth and spread of brain tumors

Recurring glioblastomas with very few mutations are far more vulnerable to immunotherapies

Recurring glioblastomas with very few mutations are far more vulnerable to immunotherapies

Study: 20% of glioblastomas are fueled by overactive mitochondria

Study: 20% of glioblastomas are fueled by overactive mitochondria

Nuclear DICER complex disrupts cytoplasmic microRNAome in glioblastoma cancer cells

Nuclear DICER complex disrupts cytoplasmic microRNAome in glioblastoma cancer cells

Heat treatment during chemotherapy is more effective at destroying cancer cells

Heat treatment during chemotherapy is more effective at destroying cancer cells

Tissue healing after brain injury could spur tumor growth

Tissue healing after brain injury could spur tumor growth

Molecular reporters produce fluorescence to expose the allies of tumor cells

Molecular reporters produce fluorescence to expose the allies of tumor cells

Anti-diarrhea drug triggers cell death in glioblastoma cells

Anti-diarrhea drug triggers cell death in glioblastoma cells

Research provides new insights into Glioblastoma invasiveness

Research provides new insights into Glioblastoma invasiveness

Study findings can guide personalized breast cancer therapies based on melatonin

Study findings can guide personalized breast cancer therapies based on melatonin

Higher degrees of necrosis are inked to poor survival in brain cancer patients

Higher degrees of necrosis are inked to poor survival in brain cancer patients

Penn study opens the door to let CAR T cells reach the tumor microenvironment

Penn study opens the door to let CAR T cells reach the tumor microenvironment

Combining cell engineering with machine learning to design living medicines for cancer

Combining cell engineering with machine learning to design living medicines for cancer

Dexamethasone use could reduce immune checkpoint inhibitor efficacy in glioblastoma patients

Dexamethasone use could reduce immune checkpoint inhibitor efficacy in glioblastoma patients

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

CRISPR/Cas9 system is highly effective in treating metastatic cancers

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Cannabidiol oils are equally or less effective at inhibiting certain cancer cell lines

Cannabidiol oils are equally or less effective at inhibiting certain cancer cell lines

Polymeric nanomicelles effectively deliver anti-cancer drugs to glioblastoma

Polymeric nanomicelles effectively deliver anti-cancer drugs to glioblastoma

Men and women may require different brain tumor therapy, study finds

Men and women may require different brain tumor therapy, study finds

Synthetic protein nanoparticle may treat aggressive brain cancer

Synthetic protein nanoparticle may treat aggressive brain cancer