Glioblastoma Multiforme News and Research

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Glioblastoma Multiforme is a fast-growing type of central nervous system tumor that forms from glial (supportive) tissue of the brain and spinal cord and has cells that look very different from normal cells. Glioblastoma multiforme usually occurs in adults and affects the brain more often than the spinal cord. Also called GBM, glioblastoma, and grade IV astrocytoma.

Study: All GA-binding proteins have the highest expression levels in secondary glioblastomas

Oncotarget published "TERT and its binding protein: overexpression of GABPA/B in high grade gliomas" which reported that all GA-binding proteins progress through the glioma grades and have the highest expression levels in secondary glioblastomas.

28 Jul 2021

Researchers receive $3.75 million to study the impact of fluid flow on CAR-T cell therapy for brain cancer

Glioblastoma multiforme is among the most lethal of cancers and the most stubborn in the face of treatment. Fewer than 20 percent of patients survive more than two years after diagnosis, according to the Central Brain Tumor Registry of the United States.

29 Apr 2021

Animal study shows how chemical compound in Indian Long Pepper works against glioblastoma

Piperlongumine, a chemical compound found in the Indian Long Pepper plant (Piper longum), is known to kill cancerous cells in many tumor types, including brain tumors.

21 Apr 2021

New nanomedicine device is effective for treating glioblastoma multiforme

A micro-sized polymeric net wrapping around brain tumors, just like a fishing net around a shoal of fish: this is the microMESH, a new nanomedicine device capable to conform around the surface of tumor masses and efficiently deliver drugs.

20 Apr 2021

Gene responsible for cholesterol dysregulation in brain cancer cells could be a target for future drugs

Most people relate cholesterol to heart health, but it is also a critical component in the growth and spread of brain cancer.

23 Mar 2021

New glioma-targeted nano-therapeutic offers a potential treatment for glioblastomas

With a survival rate of only five years, the most common and aggressive form of primary brain tumor, glioblastoma multiforme, is notoriously hard to treat using current regimens that rely on surgery, radiation, chemotherapy, and their combinations.

24 Feb 2021

New zebrafish model could help advance glioblastoma multiforme research

Scientists at the Fralin Biomedical Research Institute at VTC have identified a new zebrafish model that could help advance glioblastoma multiforme research. Glioblastoma is an aggressive form of primary brain tumor - fewer than one in 20 patients survive five years after diagnosis.

13 Feb 2021

Molecular reporters produce fluorescence to expose the allies of tumor cells

Glioblastoma is the most common malignant brain tumor in adults. Roughly five in every 100,000 people develop this type of cancer each year.

23 Dec 2020

Compound found in brown seaweeds could help treat malignant brain tumour

A compound found in brown seaweeds could help to treat one of the most common and aggressive forms of malignant brain tumour.

10 Nov 2020

Scientists identify key molecules that mediate radioresistance in aggressive brain cancer

Scientists have identified key molecules that mediate radioresistance in glioblastoma multiforme; these molecules are a potential target for the treatment of this brain cancer.

30 Sep 2020

Researchers develop novel approach for utilizing 4D-printing of arrays to accelerate drug testing

Investigators at Rutgers Cancer Institute of New Jersey have developed a novel approach for utilizing 4-dimensional (4D) printing of arrays that transform from cell-culture inserts into histological cassettes that hold patient tissue samples for rapid programmable drug testing.

12 Aug 2020

MU offers an alternative to chemotherapy for treatment of cancer in animals and humans

Osteosarcoma, a common bone cancer in dogs, affects more than 10,000 dogs in the U.S. each year. While chemotherapy is generally effective at killing some of the cancer cells, the numerous side effects can be painful and often a subset of cancer cells exist that are resistant to chemotherapy.

19 Jul 2020

Promising new approach uses natural killer cells to treat glioblastomas

Glioblastomas are the most common malignant brain tumors in adults. Treatment options are extremely limited and usually not effective, leading to death for most patients within 12-18 months of diagnosis.

9 Jul 2020

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

An interview discussing the use of spherical nucleic acids (SNAs) and what they show about the importance of structure in pharmaceutical development.

From Pittcon 2 Jul 2020

New machine learning approach classifies common type of brain tumor

A new machine learning approach classifies a common type of brain tumor into low or high grades with almost 98% accuracy, researchers report in the journal IEEE Access.

9 Jun 2020

Antimalarial drug shows promise as potential therapy for aggressive brain cancer

Glioblastoma multiforme is an aggressive form of cancer in the brain that is typically fatal. But new findings by VCU Massey Cancer Center and VCU Institute of Molecular Medicine researchers could help increase the effectiveness of the most common current treatments with the addition of lumefantrine, an FDA-approved drug used to treat malaria.

26 May 2020

Glioblastoma Multiforme News and Research

Study: All GA-binding proteins have the highest expression levels in secondary glioblastomas

Researchers receive $3.75 million to study the impact of fluid flow on CAR-T cell therapy for brain cancer

Animal study shows how chemical compound in Indian Long Pepper works against glioblastoma

New nanomedicine device is effective for treating glioblastoma multiforme

Gene responsible for cholesterol dysregulation in brain cancer cells could be a target for future drugs

New glioma-targeted nano-therapeutic offers a potential treatment for glioblastomas

New zebrafish model could help advance glioblastoma multiforme research

Molecular reporters produce fluorescence to expose the allies of tumor cells

Compound found in brown seaweeds could help treat malignant brain tumour

Scientists identify key molecules that mediate radioresistance in aggressive brain cancer

Researchers develop novel approach for utilizing 4D-printing of arrays to accelerate drug testing

MU offers an alternative to chemotherapy for treatment of cancer in animals and humans

Promising new approach uses natural killer cells to treat glioblastomas

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

New machine learning approach classifies common type of brain tumor

Antimalarial drug shows promise as potential therapy for aggressive brain cancer

Scientists developing a combined vaccine to fight most malignant brain tumor

UCI neuro-oncologist uses comprehensive approach to battle brain cancer

Cancer mutations may arise decades before diagnosis

Lab-grown brain organoids may hold the answers to personalized treatments for glioblastomas

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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