Glioma News and Research

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Glioma is a cancer of the brain that begins in glial cells (cells that surround and support nerve cells).

POT1 gene linked to glioma development mediates its effects in a sex-specific manner

Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner.

20 Apr 2021

Study may lead to new treatment for incurable brain cancer in children

Research by Australian scientists could pave the way to a new treatment for a currently incurable brain cancer in children called Diffuse Intrinsic Pontine Glioma, or DIPG. Affecting about 20 children in Australia each year, DIPG is a devastating disease with an average survival time of just nine months after diagnosis.

15 Apr 2021

Novel gene therapy reprograms glioma cells into functional neurons

Glioma is a fatal neurological disorder that has limited interventional treatment, despite extensive research over the past several decades.

24 Mar 2021

UAB researchers find potential new pathway to treating radiation-resistant glioblastoma

Researchers at the University of Alabama at Birmingham have identified a potential new pathway to treating radiation-resistant glioblastoma, one of the most aggressive forms of brain cancer.

15 Mar 2021

Proteomics analysis from aggressive human cancers can help identify potential therapeutic targets

Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets.

4 Mar 2021

New glioma-targeted nano-therapeutic offers a potential treatment for glioblastomas

With a survival rate of only five years, the most common and aggressive form of primary brain tumor, glioblastoma multiforme, is notoriously hard to treat using current regimens that rely on surgery, radiation, chemotherapy, and their combinations.

24 Feb 2021

Mice study suggests novel approach to treat a type of common glioma

Gliomas are common brain tumors that comprise about one third of all cancers of the nervous system. In a study funded by the National Institutes of Health, researchers tested a novel combination treatment approach on mice with tumors with characteristics similar to human astrocytomas--a type of slow-growing glioma--and found tumor regression in 60 percent of the mice treated.

16 Feb 2021

Scientists discover new immunotherapy target for malignant brain tumors

Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body's immune system.

15 Feb 2021

New zebrafish model could help advance glioblastoma multiforme research

Scientists at the Fralin Biomedical Research Institute at VTC have identified a new zebrafish model that could help advance glioblastoma multiforme research. Glioblastoma is an aggressive form of primary brain tumor - fewer than one in 20 patients survive five years after diagnosis.

13 Feb 2021

Revolutionary drug combination shows potential for treatment of fatal childhood cancer

Every year around 20 Australian children die from the incurable brain tumor, Diffuse Intrinsic Pontine Glioma (DIPG). The average age of diagnosis for DIPG is just seven years.

13 Feb 2021

New combination treatment approach improves overall survival in mice with glioblastoma

In a study of mice, researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new approach that combines an anti-psychotic drug, a statin used to lower high cholesterol levels, and radiation to improve the overall survival in mice with glioblastoma.

9 Feb 2021

New results challenge the current understanding of medulloblastoma

Scientists at St. Jude Children's Research Hospital and their colleagues have published a detailed account of SJMB03, a clinical trial for pediatric patients with medulloblastoma.

28 Jan 2021

New method could provide additional insight into brain tumors

A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence to better classify a tumor and the most effective treatments.

19 Jan 2021

International consortium awarded SNSF Sinergia grant to improve treatment for pediatric brain tumors

SNSF Sinergia grant awarded to research groups in Switzerland and Norway to identify novel treatment strategies for children with aggressive brain tumors.

7 Jan 2021

New device for investigating intrinsic extracellular pH dynamics in the brain

Researchers at Tohoku University have developed the first all-in-one miniature pH probe for real-time investigations of intrinsic extracellular pH dynamics in the deep brain structures.

24 Dec 2020

Miniature pH probe allows real-time analysis of pH dynamics in deep brain structures

Researchers at Tohoku University have developed the first all-in-one miniature pH probe for real-time investigations of intrinsic extracellular pH dynamics in the deep brain structures.

24 Dec 2020

New guidelines and standards for the treatment of brain tumor complications

The brain can be affected by a number of different types of tumor and this leads to serious complications such as epileptic attacks, brain edema, hemorrhage, or thrombosis.

9 Dec 2020

Tumor DNA in spinal fluid can help track children with aggressive brain tumors

For many cancers, doctors are increasingly looking to the DNA that solid tumors shed into the blood stream to help with diagnosis and monitoring. But brain cancer has been a different story thanks to the natural blockade created by the blood-brain barrier.

22 Oct 2020

Researchers develop breakthrough blood test for brain tumors

Genetic mutations that promote the growth of the most common type of adult brain tumors can be accurately detected and monitored in blood samples using an enhanced form of liquid biopsy developed by researchers at Massachusetts General Hospital.

14 Oct 2020

Researchers develop mitochondrial-targeted prodrug for treating glioblastoma

Houston Methodist researchers found that mice harboring human glioblastoma tumors in their brains had greatly enhanced survival and weight gain when given a newly developed prodrug.

9 Oct 2020