Glucocorticoid is a compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs).
Knopp Biosciences LLC today announced the publication of a report in the journal Blood that a Phase 2 study of dexpramipexole in hypereosinophilic syndromes met its co-primary endpoints.
About one in every 100 people in the world takes glucocorticoids long term to treat immune-mediated diseases. However, glucocorticoids, such as prednisone, have a side effect -- they induce the bone loss called osteoporosis, causing an estimated yearly bone fracture rate of 5 percent.
Life needs stimulation. However, overstimulation can cause exhaustion and illness. During specific sensitive periods early in life, stress can even affect later mental health.
Our bodies convert food into energy for all life activities. These metabolic processes allow the cells that make up our bodies to produce (anabolism) and consume (catabolism) energy molecules from nutrients.
Vertebrate species, including humans, exposed to stress prenatally tend to have higher stress hormones after birth, according to a new Dartmouth-led study published in Scientific Reports.
The time babies spend in the womb is far from idle. The brain is changing more rapidly during this time than at any other time in development. It is an active time for the fetus to grow and explore, and of course connect to its mother.
New research from Huntsman Cancer Institute at the University of Utah indicates steroid and hormone receptors are simultaneously active in many endometrial cancer tissues.
Diagnostic and treatment advances are helping patients with Duchenne muscular dystrophy-;one of nine major types of muscular dystrophy that affects males-;live into their 30s and beyond, raising challenges in such areas as education, vocation, levels of independence, personal relationships, emotional health, and intimacy.
Researchers at UC Davis Health and Albany Medical College have shown that the protein vascular endothelial growth factor A -- or VEGFA -- plays a major role in the inflammation and airway obstruction associated with asthma.
Fresh insights into key hormones found in commonly prescribed medicines have been discovered, providing further understanding of the medicines' side effects.
UT Southwestern Medical Center researchers have identified a chemical that suppresses the lethal form of a parasitic infection caused by roundworms that affects up to 100 million people and usually causes only mild symptoms.
What makes the body of a person or any other organism work can, for the most part, be summed up in a word: proteins.
Obesity is independently associated with worse patient-reported outcomes in women with systemic lupus erythematosus, including disease activity, depressive symptoms, pain and fatigue, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.
Opioids and selective serotonin reuptake inhibitors, a widely used group of antidepressants, are both associated with higher risk of osteoporotic fractures for patients with rheumatoid arthritis, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.
A study published in the journal Nature Neuroscience, from Nature publishing group, describes the identification of a novel molecular pathway that can constitute a therapeutic target for cognitive defects in Parkinson's disease.
New research led by The Ohio State University Wexner Medical Center found a potential therapeutic strategy to prevent infections in patients with spinal cord injuries.
A group of steroid hormones could provide new insight into the bone loss and deterioration that occurs with aging, researchers at the Medical College of Georgia at Augusta University report.
The American College of Rheumatology's updated clinical guideline for the prevention and treatment of glucocorticoid-induced osteoporosis is now available online.
Weekly doses of glucocorticoid steroids, such as prednisone, help speed recovery in muscle injuries, reports a new Northwestern Medicine study. The weekly steroids also repaired muscles damaged by muscular dystrophy.
A high-calorie diet, even without a high amount of fat, causes bone loss, and both high-calorie and high-fat diets induce excessive fat gain and insulin resistance, a new study conducted in mice finds.