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Hyperinsulinemia itself not a cause of atherosclerosis

A number of studies have shown that excess insulin circulating in the bloodstream is a major independent risk factor for cardiovascular disease. However, a new study from Joslin Diabetes Center finds that this condition, called hyperinsulinemia, is itself not a cause of atherosclerosis.

28 Mar 2012

GIK can reduce cardiac arrest or death in patients with acute coronary syndrome

Paramedics can reduce someone's chances of having a cardiac arrest or dying by 50 percent by immediately administering a mixture of glucose, insulin and potassium ("GIK") to people having a heart attack, according to research presented today at the American College of Cardiology's 61st Annual Scientific Session.

28 Mar 2012

Top-line results from two Targacept TC-6987 Phase 2 studies on asthma, type 2 diabetes

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today announced top-line results from two separate exploratory Phase 2 studies of its product candidate TC-6987 conducted in the United States, one in asthma and one in type 2 diabetes.

28 Mar 2012

Bariatric surgery better than standard medical treatment for severe type 2 diabetes

In the first published study of its kind, researchers from the Catholic University/Policlinico Gemelli in Rome, Italy, and NewYork-Presbyterian/Weill Cornell Medical Center found that bariatric surgery dramatically outperforms standard medical treatment of severe type 2 diabetes.

27 Mar 2012

ACS symposium focuses on biomimetics

Combining the secrets that enable water striders to walk on water and give wood its lightness and great strength has yielded an amazing new material so buoyant that, in everyday terms, a boat made from 1 pound of the substance could carry five kitchen refrigerators, about 1,000 pounds.

27 Mar 2012

Theracurmin shows positive impact on human diastolic functions

The research group led by Dr. Koji Hasegawa, Director of the Translational Research Division at the National Hospital Organization Kyoto Medical Center and Dr. Tatsuya Morimoto, Professor at the Molecular Medicine School of Pharmaceutical Sciences, University of Shizuoka, announced today based on the recent human clinical trials, that Theracurmin has continuously shown positive impact on human diastolic functions.

26 Mar 2012

Population-wide community and clinical prevention program reduces cardiovascular risk profile

A population-wide community and clinical prevention program involving 10,000 adults meaningfully reduced the cardiovascular (CV) risk profile among a substantial portion of the population as indicated by those participating in screenings. Findings also indicate the level of improvements differ by gender for specific cardiovascular risk factors.

26 Mar 2012

Switch may release fuel and materials for rapid growth and formation of layers that later become organs

Shortly after a mouse embryo starts to form, some of its stem cells undergo a dramatic metabolic shift to enter the next stage of development, Seattle researchers report today. These stem cells start using and producing energy like cancer cells.

26 Mar 2012

High-fat, low-carb foods linked with increased risk of heart attack in obese people

High-fat, low-carb foods are a popular choice for dieters, but new laboratory research by University of Alabama at Birmingham cardiologists indicates these may be detrimental to the health of people who have ischemic cardiovascular disease or a predisposition to heart attacks.

26 Mar 2012

Study validates Mitofusin 2 as possible target for treatment of diabetes mellitus

Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have discovered that deficiency of a single protein, Mitofusin 2, in muscle and hepatic cells of mice is sufficient to cause tissues to become insensitive to insulin, thus producing an increase in blood glucose concentrations. These are the two most common conditions prior to development of diabetes type 2.

26 Mar 2012

Insulin resistance occurs in the brains of people with Alzheimer's

Insulin resistance in the brain precedes and contributes to cognitive decline above and beyond other known causes of Alzheimer's disease, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania. Insulin is an important hormone in many bodily functions, including the health of brain cells.

26 Mar 2012

Obesity in later life linked to decreased mental faculties

The study found said out of 250 test subjects involving people over 59 years old, people between 60 and 70 who had the highest BMIs also had the lowest cognitive function. There was also a connection between visceral fat -- otherwise known as the belly fat around the torso - and poor mental abilities. The study, which was published in the British journal Age and Aging, measured the subjects fat-related measures including BMI, waist circumference and the amount of visceral - which could be close to organs - and subcutaneous -under the skin - fat using a abdominal CT scan. Cognitive ability was determined by a test called a Mini-Mental State Examination.

25 Mar 2012

Deficiency of Mitofusin 2 protein leads to insulin resistance, glucose intolerance

The study shows that the lack of Mitofusin 2 in mice produces insulin resistance and glucose intolerance, the main causes of diabetes.

23 Mar 2012

European Commission grants marketing authorization for use of BYETTA with basal insulin

Amylin Pharmaceuticals, Inc. and Eli Lilly and Company announced today that the European Commission has granted marketing authorization to BYETTA (exenatide twice-daily) as an adjunctive therapy to basal insulin, with or without metformin and/or Actos (pioglitazone), for the treatment of type 2 diabetes in adults who have not achieved adequate glycemic control with these agents.

23 Mar 2012

Blocking PFKFB4 enzyme could prevent growth of prostate cancer cells

Cancer Research UK scientists have discovered how blocking a key enzyme, which helps convert glucose into energy, could provide a new way to kill prostate cancer cells, according to a study published in the journal Cancer Discovery.

23 Mar 2012

Study provides important clue in type 1 diabetes

In type 1 diabetes (T1D), pancreatic beta cells die from a misguided autoimmune attack, but how and why that happens is still unclear. Now, JDRF-funded scientists from the Indiana University School of Medicine have found that a specific type of cellular stress takes place in pancreatic beta cells before the onset of T1D, and that this stress response in the beta cell may in fact help ignite the autoimmune attack.

23 Mar 2012

Verapamil drug may reverse diabetes-related death of pancreatic beta cells

A common high-blood-pressure medication appears to reverse the diabetes-related death of pancreatic beta cells, according to a University of Alabama at Birmingham study published today in the journal Diabetes.

23 Mar 2012

Smoking may restore self-control

Researchers at Moffitt Cancer Center in Tampa, Fla., have found that when they deplete a smoker's self control, smoking a cigarette may restore self-control.

20 Mar 2012

Peer mentor intervention improves glucose control in African American veterans with diabetes

by peer mentors has a statistically significant effect on improving glucose control in African American veterans with diabetes, according to a study by researchers at the Perelman School of Medicine at the University of Pennsylvania and the Philadelphia VA Center for Health Equity Research and Promotion.

20 Mar 2012

Americans not adhering to the 7 healthy heart recommendations

A new study of nearly 45,000 adults showed that participants who met more of seven recommended cardiovascular health behaviors or factors (such as not smoking, having normal cholesterol levels, eating a healthy diet), had a lower risk of death compared to participants who met fewer factors. The study was published in Journal of American Medical Association. The study is being published early online to coincide with its presentation at a specialty meeting of the American Heart Association.

19 Mar 2012

Glucose News and Research

Hyperinsulinemia itself not a cause of atherosclerosis

GIK can reduce cardiac arrest or death in patients with acute coronary syndrome

Top-line results from two Targacept TC-6987 Phase 2 studies on asthma, type 2 diabetes

Bariatric surgery better than standard medical treatment for severe type 2 diabetes

ACS symposium focuses on biomimetics

Theracurmin shows positive impact on human diastolic functions

Population-wide community and clinical prevention program reduces cardiovascular risk profile

Switch may release fuel and materials for rapid growth and formation of layers that later become organs

High-fat, low-carb foods linked with increased risk of heart attack in obese people

Study validates Mitofusin 2 as possible target for treatment of diabetes mellitus

Insulin resistance occurs in the brains of people with Alzheimer's

Obesity in later life linked to decreased mental faculties

Deficiency of Mitofusin 2 protein leads to insulin resistance, glucose intolerance

European Commission grants marketing authorization for use of BYETTA with basal insulin

Blocking PFKFB4 enzyme could prevent growth of prostate cancer cells

Study provides important clue in type 1 diabetes

Verapamil drug may reverse diabetes-related death of pancreatic beta cells

Smoking may restore self-control

Peer mentor intervention improves glucose control in African American veterans with diabetes

Americans not adhering to the 7 healthy heart recommendations

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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