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FDA accepts BMY and AstraZeneca's dapagliflozin NDA for review

Bristol-Myers Squibb Company and AstraZeneca today announced that the U.S. Food and Drug Administration has accepted for review a New Drug Application for dapagliflozin, an investigational compound for the treatment of adults with type 2 diabetes mellitus.

9 Mar 2011

Study: Physicians' empathy can improve patients' positive clinical outcomes

It has been thought that the quality of the physician-patient relationship is integral to positive outcomes but until now, data to confirm such beliefs has been hard to find. Through a landmark study, a research team from Jefferson Medical College of Thomas Jefferson University has been able to quantify a relationship between physicians' empathy and their patients' positive clinical outcomes, suggesting that a physician's empathy is an important factor associated with clinical competence.

8 Mar 2011

hUCBs and MenSCs transplant may offer future therapeutic benefit for AD, stroke, ALS

Transplanting stem cells derived from umbilical cord blood cells and menstrual blood cells may offer future therapeutic benefit for those suffering from stroke, Alzheimer's disease, and amyotrophic lateral sclerosis, says a team of neuroscience researchers from the University of South Florida's Department of Neurosurgery and Brain Repair and collaborators from three private-sector research groups, Saneron CCEL Therapeutics, Inc., Tampa, FL, Cryo-Cell International, Inc., Oldsmar, FL, and Cryopraxis, Cell Praxis, BioRio, Rio de Janeiro, Brazil.

8 Mar 2011

Study: Resveratrol can reduce body fat

For her thesis entitled Conjugated Linoleic Acid and Resveratrol: the effect of these functional ingredients on the metabolism of triglycerides and adiposity, Nutrition and Obesity research team member at the University of the Basque Country, Ms Arrate Lasa, studied the fat-reducing effect of CLA and resveratrol.

4 Mar 2011

Lactate plays critical role in formation of long-term memory

Researchers from Mount Sinai School of Medicine have found that lactate, a type of energy fuel in the brain, plays a critical role in the formation of long-term memory. These findings have important implications for common illnesses like Alzheimer's disease, other neurodegenerative disorders, aging-related memory impairment and diabetes. The research is published in the March 4th issue of the journal Cell.

4 Mar 2011

New insight: p53 protein controls molecular crossroads in glucose metabolic pathway

The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins.

3 Mar 2011

PositiveID reaches chemistry milestone in glucose-sensing RFID microchip development

PositiveID Corporation announced today that it has reached an important chemistry milestone in the development of its GlucoChip, glucose-sensing RFID microchip.

3 Mar 2011

New study: Lower potassium levels may help explain racial disparity in type 2 diabetes

Lower potassium levels in the blood may help explain why African-Americans are twice as likely to be diagnosed with type 2 diabetes as whites, according to a new study by Johns Hopkins researchers.

3 Mar 2011

Researchers find mineral deficiency increases type 2 diabetes risk in African-Americans

Lower potassium levels in the blood may help explain why African-Americans are twice as likely to be diagnosed with type 2 diabetes as whites, according to a new study by Johns Hopkins researchers.

2 Mar 2011

Glycogen study findings shed light on possible route to treat Lafora disease

Indiana University scientists have solved a perplexing mystery regarding one of the body's main energy storage molecules, in the process shedding light on a possible route to treatment of a rare but deadly disease in teenagers.

2 Mar 2011

Study: Pycnogenol- offers natural solution for patients with metabolic syndrome

The American Heart Association estimates 35 percent of adults in the U.S. suffer from metabolic syndrome, a group of risk factors characterized by obesity and the simultaneous presence of heart disease risk factors with high blood pressure, blood sugar and lipids.

2 Mar 2011

Gut bacteria could exert control over metabolic functions of other organs

Bacteria in the human gut may not just be helping digest food but also could be exerting some level of control over the metabolic functions of other organs, like the liver, according to research published this week in the online journal mBio-. These findings offer new understanding of the symbiotic relationship between humans and their gut microbes and how changes to the microbiota can impact overall health.

1 Mar 2011

New GuLF STUDY to look at health effects of oil spill on 55,000 cleanup workers, volunteers

A new study that will look at possible health effects of the Gulf of Mexico's Deepwater Horizon oil spill on 55,000 cleanup workers and volunteers begins today in towns across Louisiana, Mississippi, Alabama, and Florida.

1 Mar 2011

Sugary drinks and high blood pressure: Study establishes a link

A new study has found that drinking sugar-sweetened beverages such as soda pop and fruit drinks may increase blood pressure in adults. The results of the study came in Tuesday’s online issue of Hypertension, Journal of the American Heart Association.

28 Feb 2011

Researchers discover new mechanism of beta cell destruction not previously known

The death of insulin-producing beta cells in the pancreas is a core defect in diabetes. Scientists in Italy and Texas now have discovered a new way that these cells die - by toxic imbalance of a molecule secreted by other pancreatic cells.

28 Feb 2011

CTSI awards NYU one-year pilot grant to assess feasibility of hemoglobin A1C diabetes test

New York University's Clinical and Translational Science Institute has awarded an NYU nursing-dental research team a one-year pilot grant to assess the feasibility of using gingival crevicular blood from periodontal patients to gauge hemoglobin A1C -- a blood glucose measurement -- as a means of diagnosing diabetes and identifying pre-diabetes.

28 Feb 2011

Evolutionary changes may have influenced metabolism and increased risk of diabetes

Researchers at the University of California, San Diego School of Medicine and Rady Children's Hospital-San Diego say an evolutionary gene mutation that occurred in human millions of years ago and our subsequent inability to produce a specific kind of sugar molecule appears to make people more vulnerable to developing type 2 diabetes, especially if they're overweight.

25 Feb 2011

Research sheds new light on problem of insulin resistance in type 2 diabetes

A research team, led by La Jolla Institute scientist Joel Linden, Ph.D., has shed new light on the problem of insulin resistance, and identified the key participants in a molecular pathway that holds therapeutic promise for reducing the severity of type 2 diabetes.

25 Feb 2011

Maternal fructose intake during pregnancy leads to sex-specific changes in fetal, neonatal endocrinology

A recent study accepted for publication in Endocrinology, a publication of The Endocrine Society, reports for the first time that maternal fructose intake during pregnancy results in sex-specific changes in fetal and neonatal endocrinology.

25 Feb 2011

Research: Loss of CMAH's function may make humans more prone to obesity and diabetes

As if the recent prediction that half of all Americans will have diabetes or pre-diabetes by the year 2020 isn't alarming enough, a new genetic discovery published online in the FASEB Journal provides a disturbing explanation as to why: we took an evolutionary "wrong turn."

25 Feb 2011

Glucose News and Research

FDA accepts BMY and AstraZeneca's dapagliflozin NDA for review

Study: Physicians' empathy can improve patients' positive clinical outcomes

hUCBs and MenSCs transplant may offer future therapeutic benefit for AD, stroke, ALS

Study: Resveratrol can reduce body fat

Lactate plays critical role in formation of long-term memory

New insight: p53 protein controls molecular crossroads in glucose metabolic pathway

PositiveID reaches chemistry milestone in glucose-sensing RFID microchip development

New study: Lower potassium levels may help explain racial disparity in type 2 diabetes

Researchers find mineral deficiency increases type 2 diabetes risk in African-Americans

Glycogen study findings shed light on possible route to treat Lafora disease

Study: Pycnogenol- offers natural solution for patients with metabolic syndrome

Gut bacteria could exert control over metabolic functions of other organs

New GuLF STUDY to look at health effects of oil spill on 55,000 cleanup workers, volunteers

Sugary drinks and high blood pressure: Study establishes a link

Researchers discover new mechanism of beta cell destruction not previously known

CTSI awards NYU one-year pilot grant to assess feasibility of hemoglobin A1C diabetes test

Evolutionary changes may have influenced metabolism and increased risk of diabetes

Research sheds new light on problem of insulin resistance in type 2 diabetes

Maternal fructose intake during pregnancy leads to sex-specific changes in fetal, neonatal endocrinology

Research: Loss of CMAH's function may make humans more prone to obesity and diabetes

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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