Glucose News and Research

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Nanoparticles provide a targeted version of photothermal therapy for cancer

In a lecture he delivered in 1906, the German physician Paul Ehrlich coined the term Zuberkugel, or "magic bullet," as shorthand for a highly targeted medical treatment.

15 Mar 2010

Obese type 2 diabetics carry mitochondrial proteins that reduce response to physical exercise

Diet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young. A study at the Institute for Research in Biomedicine and Trinity College in Dublin demonstrates that obese subjects between 18 and 25 years of age carry mitochondrial proteins and genes that work abnormally and that these anomalies contribute to generating insulin resistance and a reduced response to physical exercise.

15 Mar 2010

Discovery of MiR-451 molecule may serve as a biomarker for brain tumor

Cancer cells in rapidly growing brain tumors must adjust to periods of low energy or die. When energy levels are high, tumor cells grow and proliferate. When levels are low, the cells grow less and migrate more.

15 Mar 2010

XOMA initiates Phase 2 clinical trial of XOMA 052 in Type 1 diabetes patients

XOMA Ltd., a leader in the discovery and development of therapeutic antibodies, announced the initiation of a Phase 2 clinical trial of XOMA 052, its antibody to interleukin-1 beta (IL-1 beta), in Type 1 diabetes patients. Funding for the trial is being provided by the Juvenile Diabetes Research Foundation International, the largest patient advocacy organization of Type 1 diabetes research worldwide.

12 Mar 2010

CoreObjects receives PMI Excellence Award for developing HbA1c Blood Sugar Analysis device

CoreObjects is proud to announce the achievement of the Project Management Institutes "Excellence Award" for their role in helping launch a product that enhances the quality of life for patients suffering from diabetes.

12 Mar 2010

Independently-conducted studies confirm significant bioavailability of orally delivered insulin

ACCESS PHARMACEUTICALS, INC. announced that it has received reports of significant bioavailability of orally delivered insulin in two independently-conducted animal studies. The studies, which confirm earlier findings, were performed as part of on-going work with commercial collaborators that are evaluating Access' Cobalamin™ Oral Drug Delivery Technology.

12 Mar 2010

Novel mutation in gene encoding ankyrin-B increases risk of type 2 diabetes

Alterations in our response to the taste or smell of food may be another culprit responsible for Type 2 diabetes, according to scientists at Duke University Medical Center who have identified the specific mechanism in human specimens and in mice.

12 Mar 2010

Sanvita deploys Pivotstream to integrate prescriber data into web-based analytics portal for sales and management

Faster, better intelligence about physicians, competitors, and markets will now enable Sanvita LLC, a leading provider of Consumer Blood Glucose products, to optimize their strategic decision making ability. Pivotstream, the on-demand analytics and business intelligence provider, integrates prescriber data into a web-based analytics portal for Sanvita sales and management.

11 Mar 2010

Insulin resistance in Hepatitis C patients: Mostly in muscle and not in liver

We have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes.

10 Mar 2010

Early administration of metformin can prevent long-term complications of diabetes: Study

The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association.

10 Mar 2010

Augmentation with ketone bodies improves cognitive function in AD patients

Accera, Inc., a biotechnology company delivering breakthrough therapies in central nervous system diseases, announced data which showed that augmentation with ketone bodies significantly improved cognitive function in Alzheimer's disease (AD) patients.

10 Mar 2010

Bristol-Myers Squibb, AstraZeneca commence SAVOR-TIMI 53 trial of ONGLYZA for type 2 diabetes

Bristol-Myers Squibb Company and AstraZeneca today announced the commencement of the “Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus” trial, a multicenter, randomized, double-blind, placebo-controlled Phase 4 study, to evaluate treatment with ONGLYZA™ (saxagliptin), a dipeptidyl peptidase-4 inhibitor, in adult type 2 diabetes patients with cardiovascular risk factors.

10 Mar 2010

ZenBio to be commercial source for popular murine 3T3-L1 cell line

ZenBio announce that they will be a commercial source for the popular murine 3T3-L1 cell line, which has been fundamental in metabolic disease research for 30 years.

10 Mar 2010

Patients taking warfarin who develop acute stroke more likely to experience brain hemorrhage

Patients already taking warfarin who develop an acute stroke appear more likely to experience a brain hemorrhage following treatment with an intravenous clot-dissolving medication, even if their blood clotting function appears normal, according to a report posted online today that will appear in the May print issue of Archives of Neurology, one of the JAMA/Archives journals.

9 Mar 2010

Taxing less healthful foods may steer adults toward healthier diets

Adults tend to eat less pizza and drink less soda as the price of these items increases, and their body weight and overall calorie intake also appear to decrease, according to a report in the March 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

9 Mar 2010

Obesity - Body's effort to protect organs from lipids' toxic effects

The collection of symptoms that is the metabolic syndrome-insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke-are all related to obesity, but, according to a review in the March 9th issue of the Cell Press publication Trends in Endocrinology and Metabolism, not in the way you probably think they are.

9 Mar 2010

HbA1c levels help predict future diabetes more accurately than fasting glucose measurements

Measurements of hemoglobin A1c (HbA1c) more accurately identify persons at risk for clinical outcomes than the commonly used measurement of fasting glucose, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health.

4 Mar 2010

Blood glucose-lowering hormone FGF21 also activates brown adipose tissue metabolism

The blood glucose-lowering hormone FGF21 is also an activator of brown adipose tissue metabolism, according to the study featured on the cover of Cell Metabolism and directed by the lecturer Francesc Villarroya of the UB's Department of Biochemistry and Molecular Biology (Faculty of Biology), the Institute of Biomedicine, and the Biomedical Research Networking Centre in Physiopathology of Obesity and Nutrition.

3 Mar 2010

Diabetics at risk: Nova Scotia limits pharmacare coverage of blood glucose test strips

The Nova Scotia government's decision to limit Pharmacare coverage of blood glucose test strips for some diabetes patients places a significant financial and health burden on these Nova Scotians and violates the fundamental principle that patients and their healthcare professionals should be able to determine how to manage treatment.

3 Mar 2010

Patient Safety Authority highlights analysis of data related to insulin medication errors

Pennsylvania healthcare facilities submitted over 2,600 event reports that involved the use of insulin products to the Patient Safety Authority where more than 52 percent led to situations in which a patient may have or actually received the wrong dose or no dose of insulin. The data raises awareness of a broader issue that is highlighted in the 2010 March Pennsylvania Patient Safety Advisory.

3 Mar 2010

Glucose News and Research

Nanoparticles provide a targeted version of photothermal therapy for cancer

Obese type 2 diabetics carry mitochondrial proteins that reduce response to physical exercise

Discovery of MiR-451 molecule may serve as a biomarker for brain tumor

XOMA initiates Phase 2 clinical trial of XOMA 052 in Type 1 diabetes patients

CoreObjects receives PMI Excellence Award for developing HbA1c Blood Sugar Analysis device

Independently-conducted studies confirm significant bioavailability of orally delivered insulin

Novel mutation in gene encoding ankyrin-B increases risk of type 2 diabetes

Sanvita deploys Pivotstream to integrate prescriber data into web-based analytics portal for sales and management

Insulin resistance in Hepatitis C patients: Mostly in muscle and not in liver

Early administration of metformin can prevent long-term complications of diabetes: Study

Augmentation with ketone bodies improves cognitive function in AD patients

Bristol-Myers Squibb, AstraZeneca commence SAVOR-TIMI 53 trial of ONGLYZA for type 2 diabetes

ZenBio to be commercial source for popular murine 3T3-L1 cell line

Patients taking warfarin who develop acute stroke more likely to experience brain hemorrhage

Taxing less healthful foods may steer adults toward healthier diets

Obesity - Body's effort to protect organs from lipids' toxic effects

HbA1c levels help predict future diabetes more accurately than fasting glucose measurements

Blood glucose-lowering hormone FGF21 also activates brown adipose tissue metabolism

Diabetics at risk: Nova Scotia limits pharmacare coverage of blood glucose test strips

Patient Safety Authority highlights analysis of data related to insulin medication errors

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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