Glycans News and Research

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Scientists solve structure of a critical innate immune system protein

Scientists at The Scripps Research Institute have solved the structure of a crucial human immune system molecule called TLR3, an acronym for Toll-like receptor three. In an upcoming issue of the journal Science, the protein is described as a large horseshoe-shaped coil composed of 23 leucine-rich repeats (LRRs).

27 Jun 2005

Available lines of human embryonic stem cells have been contaminated

Currently available lines of human embryonic stem cells have been contaminated with a non-human molecule that compromises their potential therapeutic use in human subjects, according to research by investigators at the University of California, San Diego (UCSD) School of Medicine and the Salk Institute in La Jolla, California.

24 Jan 2005

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

An international consortium of scientists lead by Dr. James Paulson of The Scripps Research Institute has created a technology that will advance our understanding of the role of complex sugar chains (glycans or carbohydrates) that decorate the surface of cells in the body.

8 Dec 2004

Scientists discover the body's own defense against H.Pylori, the cause of stomach ulcers and stomach cancer

An international team led by The Burnham Institute's Minoru Fukuda, Ph.D., has discovered that a human glycoprotein inhibits Helicobacter pylori ("H. pylori"), the bacterium that causes stomach ulcers and is linked with 90% of stomach cancers.

13 Aug 2004