Gonadotropin Hormone News and Research

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Gonadotropins are protein hormones secreted by gonadotrope cells of the pituitary gland of vertebrates.

How minerals influence women's fertility and menstrual health

Research reviews the essential role of minerals like zinc, selenium, and iron in supporting female reproductive health, emphasizing their impact on hormone regulation, ovulation, and endometrial health.

3 Apr 2024

Active management strategy helps women with early, nonviable pregnancies of unknown location

Women with early, nonviable pregnancies of unknown location who were given an active management strategy had more successful pregnancy resolutions than those given an expectant management strategy, according to a recent clinical trial published in JAMA.

13 Sep 2021

Total cessation of GnRH production by hypothalamic neurons can lead to infertility

Individual small RNAs are responsible for controlling the expression of gonadoliberin or GnRH (Gonadotropin-Releasing Hormone), a neurohormone that controls sexual maturation, the appearance of puberty, and fertility in adults.

3 May 2016

Neurocrine Biosciences reports net loss of $29.3 million for fourth quarter 2015

Neurocrine Biosciences, Inc. today announced its financial results for the quarter and year ended December 31, 2015.

12 Feb 2016

AbbVie announces initiation of first Elagolix Phase 3 study in patients with uterine fibroid

AbbVie, in cooperation with Neurocrine Biosciences, Inc., today announced the initiation of the first of two planned Phase 3 clinical studies evaluating the safety and efficacy of Elagolix alone or in combination with add-back therapy compared to placebo.

29 Jan 2016

Neurocrine Biosciences announces positive data from NBI-98854 Phase III trial in tardive dyskinesia

Neurocrine Biosciences, Inc. announced today that NBI-98854, a highly selective small molecule VMAT2 inhibitor, showed a statistically significant reduction in tardive dyskinesia during the six weeks of placebo-controlled treatment in the Kinect 3 clinical trial. This Phase III trial included moderate to severe tardive dyskinesia patients with underlying schizophrenia, schizoaffective disorder, bipolar or major depressive disorder.

8 Oct 2015

No lasting metabolic health costs from combined GH and GnRH analogue therapy

Gonadotropin-releasing hormone analogue given alongside growth hormone during puberty in order to increase adult height does not have long-term metabolic health consequences in children born small for gestational age, research shows.

1 Oct 2015

Neuroendocrine sequelae common after paediatric optic gliomas

Neuroendocrine sequelae are common following paediatric low-grade gliomas affecting the optic pathway, hypothalamus and suprasellar areas and are influenced by tumour location and treatment choice, a study shows.

1 Oct 2015

Study explores effectiveness of frontline treatments for couples with unexplained infertility

A breast cancer drug with promise for improving the chance that couples with unexplained infertility can have a baby without increasing their risk of multiple births apparently does not deliver, according to a comparative study.

24 Sep 2015

New genome-wide association study sheds light on the underlying biology of polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) has been passed down in many families for generations -- causing reproductive and metabolic health problems for millions of women around the world. Yet, its cause remains unknown despite more than 80 years of research since the disorder was first described in 1935.

20 Aug 2015

Neurocrine completes enrollment in Phase III clinical trial of NBI-98854 in tardive dyskinesia patients

Neurocrine Biosciences, Inc. announced today that it has recently completed subject randomization of the Phase III clinical trial (Kinect 3 Study) of its proprietary Vesicular Mono-Amine Transporter 2 (VMAT2) compound NBI-98854 in tardive dyskinesia patients.

13 Aug 2015

Retrieving eggs at earlier stage of fertility treatment may improve pregnancy rates for older women

IVF success rates for women aged 43 and above could improve by retrieving eggs from their ovaries at an earlier stage of fertility treatment, according to a new study published today in the Journal of Endocrinology.

12 Aug 2015

GnRH infusion recommended for adolescent hypogonadotropic hypogonadodism

Pulsatile gonadotropin-releasing hormone may be more effective than human chorionic gonadotropin for the treatment of peripubescent boys with hypogonadotropic hypogonadodism, say Chinese researchers.

27 May 2015

Long-term histrelin implant shows promise for central precocious puberty

Long-term subcutaneous histrelin implant therapy is a viable option for patients with central precocious puberty who require continuous gonadotropin-releasing hormone analogue therapy, say researchers.

1 May 2015

Neurocrine reports net loss of $1.2 million for first quarter 2015

Neurocrine Biosciences, Inc. today announced its financial results for the quarter ended March 31, 2015. For the first quarter of 2015, the Company reported a net loss of $1.2 million, or $0.01 loss per share, compared to a net loss of $11.8 million, or $0.17 loss per share, for the same period in 2014.

30 Apr 2015

Alternative treatment options for uterine fibroids

A 47-year-old African-American woman has heavy menstrual bleeding and iron-deficiency anemia. She reports the frequent need to urinate during the night and throughout the day. A colonoscopy is negative and an ultrasonography shows a modestly enlarged uterus with three uterine fibroids, noncancerous growths of the uterus.

24 Apr 2015

Neurocrine Biosciences, Mitsubishi Tanabe to develop and commercialize NBI-98854 in select Asian markets

Neurocrine Biosciences, Inc. today announced that it has entered into an exclusive collaboration and licensing agreement for the development and commercialization of its VMAT2 inhibitor, NBI-98854, in Japan and other select Asian markets with Mitsubishi Tanabe Pharma Corporation.

1 Apr 2015

No adulthood metabolic consequences of central precocious puberty

Researchers have found that girls with central precocious puberty have similar metabolic and general health to other women when they reach young to middle adulthood.

13 Mar 2015

Study calls for improved accessibility to care for transgender youth with gender dysphoria

A new study has confirmed that transgender youth often have mental health problems and that their depression and anxiety improve greatly with recognition and treatment of gender dysphoria.

9 Mar 2015

Letrozole helps restore fertility in obese, infertile men

A letrozole pill once a week restored fertility in obese, infertile men and led to their partners giving birth to two full-term, healthy babies, according to a new study from Canada. The results will be presented Thursday at the Endocrine Society's 97th annual meeting in San Diego.