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High fat, low carb diet improves Alzheimer's disease in mice

A report published today in the BioMed Central, open access journal Nutrition and Metabolism, showed that a brain protein, amyloid-beta, which is an indicator of Alzheimer's disease, is reduced in mice on the so-called ketogenic diet.

16 Oct 2005

New hormone discovery has implications for liver diseases

Researchers at UT Southwestern Medical Center have discovered that the small intestine communicates with the liver to control the production of bile acids - a finding that has great medical implications in treating people at risk for certain types of liver disease.

11 Oct 2005

Newly discovered hormone plays an important role in the digestion of fat, cholesterol, and fat-soluble vitamins

A newly discovered hormone plays an important role in the digestion of fat, cholesterol, and fat-soluble vitamins, such as vitamins A, E, and D, according to a new study in the October 2005 issue of Cell Metabolism.

11 Oct 2005

Vanadium may help prepare the body to recover speedily from infections

Dietary supplements containing vanadium are used by body builders to help beef up muscles and by some diabetic people to control blood sugar. New research now suggests the naturally occurring but easily toxic element may help prepare the body to recover speedily from infections from gram-negative organisms such as E. coli.

11 Oct 2005

Gene variation may play fundamental role in the development and spread of cancer in the body

New research shows that a small gene variation that increases the risk of inherited cancer can also arise during the development of spontaneous, or non-inherited, tumors.

9 Oct 2005

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

Subtle differences in other genes -- besides the defective gene known to cause the illness cystic fibrosis -- can significantly modify the inherited disease's severity, a large new multi-center national study has concluded.

5 Oct 2005

Common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer

A relatively common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer, and give cancer cells a growth advantage, according to a study in the October 5 issue of JAMA: The Journal of the American Medical Association.

4 Oct 2005

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Pharmaceutical companies around the world still come knocking on Renato Baserga, M.D.,'s door. And for good reason.

27 Sep 2005

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

...a discovery that could pave the way for more effective cancer treatments.

27 Sep 2005

Increlex - first major innovation in 20 years for the treatment of growth failure

Rush University Medical Center is participating in a clinical trial to evaluate the potential benefit of the first major innovation in 20 years for the treatment of growth failure.

26 Sep 2005

Tumor formation is generated by a complex interaction of both mechanical as well as chemical signals

The relationship between tissue rigidity and tumor formation is fairly well established; however, what is not so well understood is what happens on a molecular level that contributes to such stiffness.

26 Sep 2005

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Scientists from J. Craig Venter Institute, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine identified three novel mutations in two receptor tyrosine kinases in glioblastoma tumors using high throughput sequencing.

26 Sep 2005

Link between tissue tension and tumor formation

Most investigations into cancer have focused on chemical signals, but a new research study provides rare insight into how mechanical force can regulate cellular behavior.

20 Sep 2005

Simple new way to modify collagen, paving the way for better infection-fighting bandages

Collagen often pops up in beauty products and supermodel lips. But by mating collagen with a molecular hitchhiker, materials scientists at Johns Hopkins hope to create some important medical advances.

30 Aug 2005

Nitric oxide synthase plays a role in peripheral vascular disease

The enzyme nitric oxide synthase plays a role in peripheral vascular disease, a common disease that impairs the mobility of 25 percent of people over the age of 50, according to a Yale study in the Proceedings of the National Academy of Sciences (PNAS).

26 Aug 2005

Discovery of signaling component that influences spread of breast cancer cells

Researchers at the Virginia Commonwealth University Massey Cancer Center have found a new signaling component that influences movement of human breast cancer cells toward epidermal growth factor.

22 Aug 2005

Mutations in the targets of designer drugs critically influence their effectiveness

Two designer cancer drugs differed dramatically in a laboratory test comparing their ability to shut down a mutant, overactive growth signal in lung cancer cells, reports a team headed by scientists at the Dana-Farber Cancer Institute.

18 Aug 2005

Method to propagate mouse brain stem cells derived from ES cells

It's hard to grow stem cells in a dish. In particular, while it is possible to multiply mouse embryonic stem cells in culture, propagating stem cells that are specific to distinct tissues (e.g. neural stem cells) has proven to be a challenge.

16 Aug 2005

Researchers identify protein called EMP-1 that is present in the tumors of patients who fail to respond to treatment with gefitinib

By the time the human genome was mapped, cancer researchers had already begun investigating the proteins that were encoded by these newly identified genes.

9 Aug 2005

Arf gene prevents excessive growth of blood vessels in the developing eye

A gene better known for its role in preventing cancer also plays a key role in the developing embryo, where the gene prevents excessive growth of blood vessels, according to investigators at St. Jude Children's Research Hospital.

2 Aug 2005

Growth Factor News and Research

High fat, low carb diet improves Alzheimer's disease in mice

New hormone discovery has implications for liver diseases

Newly discovered hormone plays an important role in the digestion of fat, cholesterol, and fat-soluble vitamins

Vanadium may help prepare the body to recover speedily from infections

Gene variation may play fundamental role in the development and spread of cancer in the body

Particular versions of the TGFb1 gene are largely responsible for how badly the illness affects patients' lungs

Common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer

Pursuit of potential drugs and small molecules that target the IGF-1 receptor

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

Increlex - first major innovation in 20 years for the treatment of growth failure

Tumor formation is generated by a complex interaction of both mechanical as well as chemical signals

Mutations in receptor tyrosine kinases provide potential for highly-targeted cancer therapies

Link between tissue tension and tumor formation

Simple new way to modify collagen, paving the way for better infection-fighting bandages

Nitric oxide synthase plays a role in peripheral vascular disease

Discovery of signaling component that influences spread of breast cancer cells

Mutations in the targets of designer drugs critically influence their effectiveness

Method to propagate mouse brain stem cells derived from ES cells

Researchers identify protein called EMP-1 that is present in the tumors of patients who fail to respond to treatment with gefitinib

Arf gene prevents excessive growth of blood vessels in the developing eye

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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