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Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

The role of neighborhood-level disparities in determining shorter breast cancer-specific survival.

22 Apr 2024

Breakthrough research offers hope for patients with persistent Lyme disease symptoms

Tulane University researchers have identified a promising new approach to treating persistent neurological symptoms associated with Lyme disease, offering hope to patients who suffer from long-term effects of the bacterial infection, even after antibiotic treatment.

18 Apr 2024

Vaccines targeting chronic diseases show promise in combatting age-related conditions

Vaccine-based therapeutics for age-related disorders.

17 Apr 2024

Placental IGFBP1: A key factor in development of gestational diabetes

A new study led by the Harvard Pilgrim Health Care Institute has identified that a deficit in the placental expression of the gene insulin-like growth factor 1 (IGFBP1) and low IGFBP1 circulating levels are associated with insulin resistance during pregnancy, highlighting a potential risk factor for the development of gestational diabetes.

16 Apr 2024

Ketamine's rapid impact on depression linked to immune system pathways

Study reveals ketamine's potent anti-inflammatory effects on neurological disorders, showing promise for treating major depressive disorder through modulation of neuroimmune pathways.

15 Apr 2024

Vosoritide's first phase 2 study shows increased growth in children with hypochondroplasia

Vosoritide's first global phase 2 study showed an average increased growth rate of 1.8 cm per year in children with hypochondroplasia, a genetic cause of short stature in children, according to researchers from Children's National Hospital.

13 Apr 2024

Study reveals inflammation's role in long COVID's lingering effects

Large-scale study found that long COVID patients exhibit sustained inflammation and specific immune responses associated with varying symptoms, highlighting the importance of personalized treatment approaches.

9 Apr 2024

Research identifies how leukemia develops resistance to first line treatments

Relapses in a common form of leukemia may be preventable following new research which has identified how the cancer develops resistance to first line treatments.

9 Apr 2024

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

Anti-inflammatory therapy shows promise to treat patients following acute myocardial infarction

Research into the protective effects of two anti-inflammatory molecules, transforming growth factor-beta1 (TGFβ1) and Heligmosomoides polygyrus TGM (HpTGM), following heart attack found that both proteins reduced the inflammatory response within the injured heart and reduced mature scarring.

4 Apr 2024

The whey to go: Researchers unlock the potential of whey-derived proteins for cancer prevention

The current evidence regarding the significance of whey protein for cancer prevention and treatment.

4 Apr 2024

Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

A team of researchers from Hiroshima University has discovered a molecule that promotes the production of cancer cells. This molecule may prove to be a potential therapeutic target in the treatment of triple-negative breast cancer, an aggressive form of breast cancer.

27 Mar 2024

Focusing on oncogenic driver mutations and resistance mechanisms in the treatment of NSCLC

Lung cancer is the leading cause of cancer-related death worldwide. Improved understanding of driver mutations of non-small cell lung cancer (NSCLC) has led to more biomarker-directed treatment for patients with advanced stages.

26 Mar 2024

Vitamin D receptor presence in breast cancer tumors linked to better survival outcomes

Research identifies vitamin D receptors (VDR) in breast cancer tumors as a promising prognostic marker, linking VDR presence to tumor characteristics, survival outcomes, and potentially informing treatment strategies.

25 Mar 2024

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

A study assessed the effect of tobacco smoking and electronic cigarette (e-cigarettes) use on DNA methylation changes associated with carcinogenesis.

25 Mar 2024

Advancing precision personalized medicine for gastric cancer with 3D bioprinting

Gastric cancer ranks among the most widespread diseases in Asian populations, with South Koreans experiencing the third-highest incidence globally in 2020, as reported by the International Agency for Research on Cancer.

21 Mar 2024

Hearing loss linked to accelerated Alzheimer's progression via GDF1 pathway

Study unveils the GDF1 signaling pathway's role in mitigating the adverse effects of hearing loss on Alzheimer's disease, spotlighting potential avenues for therapeutic development.

20 Mar 2024

Lactate's role in driving cancer cachexia uncovered

Study highlights the significant role of lactate in promoting cancer cachexia via activation of the adipose-specific G-protein-coupled receptor 81 (GPR81), suggesting new therapeutic targets for this condition.

20 Mar 2024

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

New data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug, pembrolizumab, to chemotherapy before and after surgery for breast cancer leads to better outcomes for patients regardless of their age or menopausal status.

20 Mar 2024

Osteoporosis model rats show improved healing with FGF-2 treatment

A study investigating the effects of local application of fibroblast growth factor (FGF-2) on periodontal healing in osteoporosis model rats was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.

19 Mar 2024

Growth Factor News and Research

Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

Breakthrough research offers hope for patients with persistent Lyme disease symptoms

Vaccines targeting chronic diseases show promise in combatting age-related conditions

Placental IGFBP1: A key factor in development of gestational diabetes

Ketamine's rapid impact on depression linked to immune system pathways

Vosoritide's first phase 2 study shows increased growth in children with hypochondroplasia

Study reveals inflammation's role in long COVID's lingering effects

Research identifies how leukemia develops resistance to first line treatments

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Anti-inflammatory therapy shows promise to treat patients following acute myocardial infarction

The whey to go: Researchers unlock the potential of whey-derived proteins for cancer prevention

Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

Focusing on oncogenic driver mutations and resistance mechanisms in the treatment of NSCLC

Vitamin D receptor presence in breast cancer tumors linked to better survival outcomes

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

Advancing precision personalized medicine for gastric cancer with 3D bioprinting

Hearing loss linked to accelerated Alzheimer's progression via GDF1 pathway

Lactate's role in driving cancer cachexia uncovered

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

Osteoporosis model rats show improved healing with FGF-2 treatment

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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