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Topical treatment wipes out herpes with RNAi

Whether condoms or abstinence, most efforts to prevent sexually transmitted diseases have a common logic: keep the pathogen out of your body altogether.

21 Jan 2009

Potential new target in the war on HIV/AIDS

The study revealed that a variant of a protein involved in HIV pathogenesis can suppress production of an HIV protein, known as Nef. Nef is required for the human immunodeficiency virus to develop into AIDS through a series of complex events involving viral elements and cellular proteins. Nef has never been a target for drug treatment in HIV patients.

21 Jan 2009

Topical microbicide protects against genital herpes

A topical microbicide that silences two genes can safely protect against genital herpes infection for as long as one week, according to a joint study by researchers at the Albert Einstein College of Medicine of Yeshiva University and Harvard Medical School.

21 Jan 2009

Too much weight loss can be a bad thing

Doctors are not doing enough to pick up on problems with excessive weight loss, says a Saint Louis University physician who helped draft recent guidelines to diagnose the condition called "cachexia" (kuh-kex-ee-uh).

21 Jan 2009

Kidney transplant survival can be long-term for people with HIV

A Johns Hopkins study finds that HIV-positive kidney transplant recipients could have the same one-year survival rates for themselves and their donor organs as those without HIV, provided certain risk factors for transplant failure are recognized and tightly managed.

19 Jan 2009

Mutant host cell protein sequesters critical HIV-1 element

Scientists have identified a new way to inhibit a molecule that is critical for HIV pathogenesis.

19 Jan 2009

Blood type - new weapon in battle against HIV infection

Researchers have discovered a potentially important new resistance factor in the battle against HIV: blood types.

12 Jan 2009

Discovery of new regulatory circuit controlling immune cell production in mice

Using a mouse model, researchers have shown that elevated levels of a small protein known as interleukin 7 (IL-7) plays a central role in regulating the production of a type of white blood cell that is required for effective immune responses.

12 Jan 2009

New hope for transplant recipients and AIDS patients

A researcher from the Université de Montréal and the Maisonneuve-Rosemont Hospital has discovered the mechanism that prevents the regeneration of CD4+ T lymphocytes, which are white cells that are required for the proper functioning of the immune system.

12 Jan 2009

New nasal spray vaccine shown to be effective against botulism

A preclinical study found a new nasal spray vaccine to provide complete protection against a major botulism toxin, according to a study published today in the Nature journal Gene Therapy .

8 Jan 2009

Experts warn Australia is surrounded by a ring of disease hot-spots

Australian biosecurity experts have warned that Australia is surrounded to its north by a 'ring of fire' where new human and animal plagues could appear with very little warning and with potentially dire consequences.

6 Jan 2009

Prolonged nevirapine in breast-fed babies prevents HIV infection but leads to drug-resistant HIV

Babies born to HIV-positive mothers and given the antiretroviral drug nevirapine through the first six weeks of life to prevent infection via breast-feeding are at high risk for developing drug-resistant HIV if they get infected anyway, a team of researchers report.

5 Jan 2009

Pneumococcal polysaccharide vaccines do not appear to protect against pneumonia

Commonly used pneumococcal polysaccharide vaccines do not appear to be effective for preventing pneumonia, found a study by a team of researchers from Switzerland and the United Kingdom.

5 Jan 2009

Final FDA approval for generic version of antiretroviral Zerit capsules

Mylan Inc. has announced that Matrix Laboratories Limited, its India-based subsidiary in which it holds a 71.5% controlling interest, received final approval from the U.S. Food and Drug Administration (FDA) on December 29, for its Abbreviated New Drug Application (ANDA) for Stavudine Capsules USP, 15 mg, 20 mg, 30 mg and 40 mg.

1 Jan 2009

May hepatic granulomas be part of the histological spectrum of chronic hepatitis C?

While older large series of patients with hepatic granulomas have found sarcoidosis and tuberculosis to be the most common causes of hepatic granulomas, recent works have noted some patients with chronic hepatic C and hepatic granulomas and no other obvious associations.

30 Dec 2008

Family rejection of lesbian, gay and bisexual children linked to poor health in early childhood

For the first time, researchers have established a clear link between family rejection of lesbian, gay and bisexual (LGB) adolescents and negative health outcomes in early adulthood.

30 Dec 2008

HIV carriers in Malaysia should not be allowed to marry, says government official

One of Malaysia's top politicians has apparently suggested that HIV carriers should not be allowed to marry in order to avoid having sick children.

22 Dec 2008

Trends in sexual behaviors similar for teens who take few health risk and those who take many

Adolescent health risk behaviors often occur together, suggesting that youth involvement with one risk behavior may inform understanding of other risk behaviors, but in a study to examine the association between involvement in non-sexual risk behaviors and trends among sexual behaviors, Mailman School of Public Health researchers found that sexual behaviors vary considerably between those youth engaged in no risk health behaviors and those engaged in multiple health risk behaviors.

22 Dec 2008

Male circumcision may help prevent human papillomavirus infection

Two new studies suggest that male circumcision may assist in the prevention of human papillomavirus (HPV) infection, particularly infection with the high-risk subtypes associated with cervical, penile, and other cancers.

17 Dec 2008

Circumcision reduces risk of HIV infection in heterosexual men

A new U.S. study has found that being circumcised significantly reduced the risk of HIV infection in heterosexual African American men known to have been exposed to the virus.

17 Dec 2008