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New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections in Seattle, a leading annual conference of HIV research, clinical practice and progress.

24 Feb 2017

Only subset of mother's HIV virus infects infants during pregnancy or breastfeeding, research shows

In the transmission of HIV-1 from mother to child only a subset of a mother's viruses infects their infants either in utero or via breastfeeding, and the viruses that are transmitted depend on whether transmission occurs during pregnancy or through breastfeeding, according to UCLA-led research.

15 Feb 2017

First large-scale clinical study of long-acting injectable HIV drug begins

The first large-scale clinical trial of a long-acting injectable drug for HIV prevention began today.

21 Dec 2016

Penn researchers pinpoint some effective HIV drugs in causing neuronal damage

Antiretroviral drugs have been life-changing therapies for HIV patients, but they can have significant side effects.

16 Dec 2016

Scientists develop genetically engineered T cells with fusion inhibitor to disrupt HIV's harpoon

When HIV attacks a T cell, it attaches itself to the cell's surface and launches a "harpoon" to create an opening to enter and infect the cells.

18 Nov 2016

New research examines use of nanotechnology to improve delivery of drugs to HIV patients

New research led by the University of Liverpool aims to improve the administration and availability of drug therapies to HIV patients through the use of nanotechnology.

21 Oct 2016

MU researcher awarded $3 million NIH grant to develop new drugs for treating HBV

Hepatitis B (HBV) is a viral infection that increases the likelihood of developing liver cancer or liver failure.

26 Sep 2016

Hitchhiking of drugs on incorrect targets can cause adverse side effects

It probably isn't surprising to read that pharmaceutical drugs don't always do what they're supposed to. Adverse side effects are a well-known phenomenon and something many of us will have experienced when taking medicines.

26 Aug 2016

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

Neutron crystallography allows us to determine the three-dimensional structures of biological macromolecules, such as proteins, by means of the diffraction of neutrons from the regularly spaced atoms of a crystal.

21 Jul 2016

Innovative computer HIV capsid model provides real insight into virus maturation process

From a virus's point of view, invading our cells is a matter of survival. The virus makes a living by highjacking cellular processes to produce more of the proteins that make it up.

16 Jun 2016

Understanding structure of HIV-1 protease vital to development of next-generation HIV drugs

HIV, the virus that causes AIDS, has become one of the world’s most serious health and development challenges.

24 May 2016

Two Johns Hopkins scientists named among 105 winners of Presidential Early Career Awards

Namandje Bumpus, Ph.D., and Jordan Green, Ph.D., of the Johns Hopkins University School of Medicine are among 105 winners of Presidential Early Career Awards for Scientists and Engineers, which were announced by the White House on Feb. 18.

23 Feb 2016

New discovery may help researchers tackle mitochondrial diseases and age-related diseases

Buck Institute faculty Judith Campisi, PhD, says age researchers need to stop thinking of cellular senescence, now accepted as an important driver of aging, as a single phenotype that stems from genotoxic stress. Research from her lab reveals that cellular senescence, a process whereby cells permanently lose the ability to divide, is also induced by signaling from dysfunctional mitochondria - and that the arrested cells secrete a distinctly different "stew" of biologically active factors in a process unrelated to the damaging free radicals that are created in mitochondria as part of oxygen metabolism.

13 Jan 2016

Researchers use quick screening method to identify, test promising anti-Ebola drugs

A quick screening method has been used for the first time in a standard open laboratory to identify and test promising anti-Ebola drugs. This approach increases the possibility of finding new therapies faster.

12 Jan 2016

12 months of liquid formula HIV drugs protect breastfeeding babies against HIV infection

A study from four countries in Africa, published in The Lancet, shows that providing babies with up to 12 months of liquid formula HIV drugs, while breastfeeding with their HIV-positive mothers, is highly effective at protecting them from infection, including in the 6–12 month period after birth which has not been analysed in previous research.

20 Nov 2015

Drug interactions in placenta may increase risk of birth defects or stunting fetal growth

To date, studies in pregnant women examining transport of drugs across the placenta are rare and inadequate, said Tomo Nabekura, PhD. Such knowledge could be vital to preserving fetal health. In a new laboratory study, Nabekura and colleagues have illuminated a piece of this puzzle, and the results hint that mothers taking new anti-hepatitis C and/or anti-HIV drugs along with anti-hypertensives or non-steroidal anti-inflammatories (NSAIDs) could be raising the risk of birth defects or stunting fetal growth, respectively.

15 Oct 2015

Nurse-trainer uses new approach to teach correct combination of HIV drugs to Angola's nurses

Nurse-trainer Helena Cumbelembe Inacio was struggling to teach nurses at the health center here the correct combination of medicines to prevent pregnant women with HIV from passing the infection to their children.

11 Sep 2015

Southern Research receives $22 million to support HIV cure initiative

Southern Research has been awarded a seven-year contract of up to $22 million to support research that could contribute to the cure of HIV disease. Under this contract, Southern Research will develop and standardize assays that quantitate latent reservoirs of HIV.

7 Jul 2015

Clinical trial suggests HIV patients should start therapy sooner rather than later

Findings from a large-scale clinical trial have shown that people with HIV should start antiretroviral therapy as soon as they have been diagnosed, irrespective of what their CD4+ count is...

28 May 2015

Bio-Rad grants Beckman Coulter exclusive distribution rights for access HIV and Hepatitis C assays

Bio-Rad is extending its agreement with Beckman Coulter and has named the company exclusive global distributor of Bio-Rad’s Access HIV combo assay and the Access hepatitis C virus (HCV) assay in select geographies...

From Beckman Coulter Diagnostics 21 Apr 2015