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Atrial fibrillation more difficult to identify in blacks than whites; might explain lower prevalence, study finds

Limitations in the methods used to diagnose atrial fibrillation -- periods of irregular heartbeat -- in population-based studies might explain why findings indicate that atrial fibrillation is less common among blacks than whites, according to a study published in the journal Stroke, Reuters Health reports.

12 May 2009

High levels of estradiol hormone in men with heart failure linked to increased risk of death

Men with systolic chronic heart failure who have low or high levels of estradiol, a form of the hormone estrogen, have an increased risk of death compared with men with moderate levels of this hormone, according to a study in the May 13 issue of JAMA, the Journal of the American Medical Association.

12 May 2009

Aspirin lowers risk of stroke in peripheral artery disease

An analysis of previous studies indicates that among patients with peripheral artery disease, aspirin use is associated with a statistically nonsignificant decrease in the risk of a group of combined cardiovascular events (nonfatal heart attack, nonfatal stroke, and cardiovascular death), but is associated with a significant reduction in the risk of one of these events, nonfatal stroke, although the findings may be limited by the lack of a large study population, according to an article in the May 13 issue of JAMA, the Journal of the American Medical Association.

12 May 2009

Researchers develop a dynamic heart system

A new machine developed at North Carolina State University makes an animal heart pump much like a live heart after it has been removed from the animal's body, allowing researchers to expedite the development of new tools and techniques for heart surgery.

12 May 2009

Schering-Plough starts patient enrollment in phase 3 trial for Acadesine

Schering-Plough Corporation today announced the start of patient enrollment in RED-CABG, the Phase 3 Trial for acadesine, an investigational, potentially first-in-class adenosine regulating agent (ARA). Acadesine was licensed from PeriCor Therapeutics, Inc., a privately held specialty biopharmaceutical company.

12 May 2009

Sinobiopharma announces Chinese approval of Perindopril

Sinobiopharma, Inc. has announced that it has received approval from the Chinese State Food and Drug Administration (SFDA) to manufacture and market its formulation of Perindopril, an anti-hypertension drug.

12 May 2009

DHEA supplement combined with vitamin D and calcium significantly improves spinal bone density in older women

"The results of our study are very promising. Similar studies have demonstrated much smaller benefits for bone than we found. However, calcium and vitamin D deficiencies, which are present in half of older adults, may have prevented DHEA from improving bone density in the earlier studies," said Edward Weiss, Ph.D., associate professor of nutrition and dietetics at Saint Louis University's Doisy College of Health Sciences and lead author of the study.

12 May 2009

Job losses have negative effect on health, study finds

Workers who lost their job through no fault of their own were twice as likely as continuously employed workers to report over the next 18 months that they developed a new illness, such as high blood pressure, diabetes or heart disease, according to a study released last week, the New York Times reports.

12 May 2009

Omega-three fatty acid rich foods lower risk for eye disease

Regularly eating fish, nuts, olive oil and other foods containing omega-three fatty acids and avoiding trans fats appears to be associated with a lower risk for the eye disease age-related macular degeneration, according to two reports in the May issue of Archives of Ophthalmology.

12 May 2009

DASH diet to lower blood pressure also reduces women's risk of heart failure

The DASH diet was initially developed to help patients lower their blood pressure, but a large study led by investigators at Beth Israel Deaconess Medical Center (BIDMC) demonstrates that women who followed the diet also significantly reduced their risk of developing heart failure.

12 May 2009

New evidence of how high glucose damages blood vessels could lead to new diabetes treatments

New evidence of how the elevated glucose levels that occur in diabetes damage blood vessels may lead to novel strategies for blocking the destruction, Medical College of Georgia researchers say.

12 May 2009

New Centre to target health and well being of children and young people

Children and young people in the UK are set to benefit from a new centre of excellence focused on tackling health issues of most concern to them.

12 May 2009

High-caloric exercise reduces risks in heart patients the most

An exercise program that burns a lot of calories reduced cardiac risk factors better than standard cardiac rehabilitation in overweight coronary patients, researchers report in Circulation: Journal of the American Heart Association.

12 May 2009

More patients needed in clinical trials to find treatment for patent foramen ovale (PFO)

The American Heart Association and the American College of Cardiology are calling on doctors to enroll more patients in clinical trials for catheter-based closure of patent foramen ovale (PFO), a condition caused when an opening between the two chambers of the heart fails to close at birth.

12 May 2009

Smoking makes it harder for brain blood flow to recover from long-term heavy drinking

Alcohol-use disorders (AUDs) can damage the brain, particularly the frontal and parietal cortices, although this damage is at least partially reversible with sustained abstinence from alcohol. Chronic smoking is extremely common among individuals with AUDs.

12 May 2009

New genetic clues to treatment of hypertension

An international research team has identified a number of unsuspected genetic variants associated with systolic blood pressure (SBP), diastolic blood pressure (DBP), and hypertension (high blood pressure), suggesting potential avenues of investigation for the prevention or treatment of hypertension.

12 May 2009

FHL2 protein regulates blood vessel maintenance

In a study led by Akiko Hata, PhD, of Tufts University School of Medicine, researchers have shown that a protein expressed in the heart, FHL2, inhibits the genes necessary for the quiescence of vascular smooth muscle cells (vSMCs), which line blood vessels.

12 May 2009

Seniors need more sun!

Spending more time in the sunshine could help older people to reduce their risk of developing heart disease and diabetes.

11 May 2009

Self-reported diagnosis of heart disease: Less than one in five heart problems are diagnosed before symptoms appear

Clinicians are missing golden opportunities to identify heart disease before patients start displaying symptoms, according to a study of 13,877 people published in the May issue of UK-based IJCP, the International Journal of Clinical Practice.

11 May 2009

Discovery of major new treatment target in diseased arteries

Removing a single protein prevents early damage in blood vessels from triggering a later-stage, frequently lethal complication of atherosclerosis, according to research published online today in the journal Nature Medicine. By eliminating the gene for a signaling protein called cyclophilin A (CypA) from a strain of mice, researchers were able to provide complete protection against abdominal aortic aneurysm (AAA).

11 May 2009