Heart Attack News and Research

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Possible alternatives found for Vioxx and Celebrex

According to Canadian and American researchers they have identified one reason why drugs like Celebrex and Vioxx - once popular for the treatment of pain and inflammation - cause heart problems.

18 Apr 2006

Researchers clarify the mechanism by which drugs like Celebrex and Vioxx cause heart problems

Researchers at the University of Pennsylvania School of Medicine have clarified the mechanism by which drugs like Celebrex and Vioxx cause heart problems, in multiple animal models.

18 Apr 2006

Only 43 percent of older people with diabetes receive medicines that could protect their heart and kidneys

...despite the fact that virtually all of them could benefit from those drugs, a new University of Michigan study finds. And even among those with the most to gain from the medicines, the rate of use barely reaches 53 percent.

18 Apr 2006

Placental growth factor may help body repair heart attack damage

Heart attack patients produce higher levels of a natural substance in the body that plays a role in the growth of new blood vessels and this over-expression of placental growth factor (PlGF) may help reduce damage to the heart muscle

17 Apr 2006

Evista may be a better option than Tamoxifen for reducing breast cancer risk

According to drug company Lilly it's osteoporosis drug Evista is as effective as Tamoxifen in reducing the risk of breast cancer in high-risk women.

17 Apr 2006

Approval of integrated insulin pump and continuous glucose system a significant step towards artificial pancreas technology

The Juvenile Diabetes Research Foundation (JDRF) has said that the federal government's approval of an insulin pump that also provides real-time, continuous glucose monitoring is a significant step on the path to the development of an artificial pancreas, with the potential to significantly improve diabetes care and lower the risk of complications.

13 Apr 2006

Angiotension-converting enzyme inhibitors may reduce cardiovascular risk

Angiotension-converting enzyme (ACE) inhibitors, medications commonly used to treat hypertension (high blood pressure), may reduce cardiovascular risk and the risk of death in patients with coronary artery disease, according to a new analysis of previously conducted clinical trials reported in the Archives of Internal Medicine.

13 Apr 2006

No evidence that taking estrogen alone increases the risk of breast cancer in postmenopausal women

The findings come three years after a related WHI study found that a different type of hormone therapy - which combined estrogen and progestin - did result in a higher risk of breast cancer among postmenopausal women.

13 Apr 2006

A drink or two a day may be associated with better cognitive function in women

"Women who had up to two drinks a day scored about 20 percent higher on the Mini Mental State Exam (MMSE) than women who didn't drink at all or who consumed less than one drink a week," said Clinton Wright, M.D., M.S., lead author of the study.

13 Apr 2006

Sildenafil improves blood flow after heart attack in an animal model

Dogs treated with sildenafil, a drug most commonly used to treat erectile dysfunction, had better blood flow in coronary arteries than control animals, following an induced artery obstruction and treatment that modeled a heart attack and standard medical care given to people

13 Apr 2006

How you wake up might explain near death experiences

According to a new study, people who have had near death experiences often have different arousal systems controlling the sleep-wake states than people who have never had such an experience.

12 Apr 2006

Prostate cancer risk linked to high cholesterol

Italian Researchers say they have found what they believe to be the first direct link between high cholesterol levels and prostate cancer.

12 Apr 2006

Estrogen-alone hormone therapy does not increase the risk of breast cancer in postmenopausal women

The results contrast with the previously reported WHI Estrogen plus Progestin Trial, which found an increase in breast cancer over about 5 years among those taking combined hormone therapy.

11 Apr 2006

REM state intrusion contributes to near death experiences

People who have had near death experiences often have different arousal systems controlling the sleep-wake states than people who have not had a near death experience, according to a new study published in the April 11, 2006, issue of Neurology, the scientific journal of the American Academy of Neurology.

11 Apr 2006

Guidelines for medication withdrawal

Although thousands of scientific papers evaluate and compare new and established drugs each year, providing evidence to help doctors prescribe safe and effective doses, almost no studies focus on when or how to stop these medications, even late in life.

11 Apr 2006

MPD Foundation funds research for incurable blood disorders

The Myeloproliferative Disorders Foundation has awarded $750,000 to establish the MPD Research Alliance, a collaboration of the University of Illinois at Chicago, Harvard Medical School and Mayo Clinic to accelerate drug development for incurable, progressive bone marrow disorders.

11 Apr 2006

Discovery of a new mechanism for the neurodegenerative effects of amphetamines

University of Toronto study finds amphetamines are converted in the brain into free radicals whose effects manifest and linger long after the amphetamine has left the body.

7 Apr 2006

Staggering costs of sleep disorders and sleep deprivation on the nation

According to a new report by the Institute of Medicine ( IOM), 50 to 70 million Americans suffer from a disorder of sleep and wakefulness, which adversely affects daily functioning, health and longevity.

5 Apr 2006

Prostate drug doxazosin blocks receptor in heart muscle, increasing risk of heart failure

Doxazosin, a drug commonly prescribed to help improve urinary flow in men with enlarged prostates, increases the likelihood of heart failure by blocking specific receptors in heart muscle cells, according to a study conducted at the San Francisco VA Medical Center.

4 Apr 2006

High levels of HDL cholesterol more important than low levels of LDL in protecting against heart attack

The researchers looked at the history of heart disease, age, sex, race, weight and other heart disease risk factors in almost 7,000 patients. The patients were predominately inner city residents and included a large number of African Americans, women, smokers and overweight people.

4 Apr 2006