Heart Defect News and Research

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Researchers test experimental drug Neuprex on infants undergoing heart surgery

UT Southwestern Medical Center is the only institution in the nation approved by the Food and Drug Administration to test an experimental drug on infants undergoing heart surgery to see whether it can help them avoid potentially lethal infections and improve survival.

22 Aug 2005

U.S. company wants to commercialise breast milk

It has long been acknowledged that breast milk, with its minerals, digestive enzymes and antibodies, keeps babies healthy and boosts their intelligence.

7 Aug 2005

Researchers discover type of "fuel" that the heart uses can contribute to the severity of heart failures

Researchers have determined how metabolic pathways differ between healthy and failing hearts. Normally, a heart derives its energy from a balance of fatty acids and carbohydrates, specifically glucose.

21 Jul 2005

Quintuplets born to surrogate mother

In what is believed to be a world first, a surrogate mother has given birth to quintuplets.

26 Apr 2005

Infants under one year of age can accept heart transplants from donors of different blood groups

A study showing that infants under one year of age can accept heart transplants from donors of different blood groups without the risk of organ rejection means a better chance of survival for infant patients and more efficient use of donor organs overall.

4 Apr 2005

Treatment of cardiac lesions without anaesthesic

Navarre University Hospital has introduced a novel technique for the treatment of congenital heart defects and involving the percutaneous closure of the patent foramen ovale (PFO) with monitoring through intracavernous ecography.

23 Mar 2005

Abnormal brain structure tied to spatial, numerical thinking problems when children lack part of chromosome

Certain genetic diseases affect children's educational abilities in a distinctive pattern: impairing their numerical abilities more than their verbal skills. New research sheds light on this split in abilities by investigating how differences in brain structures may influence how the mind works.

3 Mar 2005

First evidence of cardiac progenitor cells

The first evidence of cardiac progenitor cells – rare, specialized stem cells located in the newborn heart of rats, mice and humans – has been shown by researchers at the University of California, San Diego (UCSD) School of Medicine. The cells are capable of differentiation into fully mature heart tissue.

10 Feb 2005

Investigation of possible link between migraine and a common heart defect, called a patent foramen ovale (PFO)

Doctors have received approval to investigate the possible link between migraine headache and a common heart defect, called a patent foramen ovale (PFO), which research indicates is prevalent in up to 25% of the general population or 15 million people in the UK.

16 Jan 2005

Glia cells may be essential for the normal development of nerve cells responsible for hearing and balance

Traditionally viewed as supporting actors, cells known as glia may be essential for the normal development of nerve cells responsible for hearing and balance, according to new University of Utah research. The study is reported in the January 6, 2005 issue of Neuron and is co-authored by scientists at the University of Washington.

6 Jan 2005

Patient safety measures work at children’s hospitals

In recent years, children's hospitals have joined in the national push to improve patient safety and avoid preventable problems. But it has been hard to measure progress, because of uncertainty about whether standard patient safety measurement tools apply to their patients, who are younger, smaller and on average sicker than those at other hospitals.

4 Jan 2005

Study evaluates new stroke prevention treatment

Doctors at Wake Forest University Baptist Medical Center are evaluating a new treatment designed to prevent strokes caused by a small heart defect.

21 Dec 2004

Research in children has shown that blood loss after heart surgery can be minimized if fresh whole blood is used for transfusions

A standard medical practice at some of the nation's largest children's hospitals – using whole, recently donated blood for certain infant open heart surgeries – may do more harm than good.

13 Oct 2004

Genetic discovery may hold clues to the development of many cases of the most common cancers

In a study published in Nature Genetics today, a team of scientists at The Institute of Cancer Research have discovered a gene that may hold clues to the development of many cases of the most common cancers including lung, breast, prostate and colon cancers.

12 Oct 2004

Fathers' occupational exposures may play an important role in the development of birth defects

Can exposure to hazardous substances at work contribute to the development of birth defects? If so, then fathers' occupational exposures may play a more important role than mothers' exposures

20 Sep 2004

Research crucial in determining what gene mutations might lead to congenital cardiovascular defects

According to the American Heart Association, congenital cardiovascular defects, such as congenital heart disease (CHD), are present in about one percent of live births and are the most common malformations in newborns.

9 Sep 2004

Parents and siblings of infants born with severe abnormalities of the left side of the heart should also be screened for heart problems

Brothers and sisters as well as parents of infants born with severe, life-threatening abnormalities of the left side of the heart should be screened for less severe, but related, heart problems, said researchers at Baylor College of Medicine in Houston.

7 Sep 2004

Blood vessel plug - amplatzer ductal occluder, performs well in trial

In the largest and longest trial yet of a device called the Amplatzer ductal occluder, a duct that shunts blood flow away from the lungs during fetal development but sometimes fails to close after birth, was successfully closed in almost all patients, according to a new study in the Aug. 4, 2004, issue of the Journal of the American College of Cardiology.

5 Aug 2004

Iraqi child undergoes heart surgery in New York

Four-year old Bra’a Hussein’s heart will never be the same following recent surgery at NYU Medical Center to correct a highly complex congenital heart condition called tetralogy of fallot.

19 Jul 2004

Cornelia de Lange syndrome gene discovered

An international team of researchers has discovered the gene for Cornelia de Lange syndrome, a disabling, multisystem genetic disease that affects an estimated one in 10,000 children.

20 Jun 2004