Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

New guidelines for cardiac specialists

A series of new guidelines for cardiac specialists has been developed to determine when heart failure patients should receive a mechanical heart-pumping device.

18 Apr 2011

Boehringer Ingelheim's dabigatran etexilate receives positive opinion from EMA committee

Boehringer Ingelheim's novel oral anticoagulant dabigatran etexilate, received a positive opinion from the European Medicines Agency's medicinal committee today.

16 Apr 2011

Patients with heart failure can benefit from left ventricular assist device

Non-cardiac surgery can be performed safely in patients with a heart device typically implanted into patients waiting for a transplant, according to a study at Henry Ford Hospital in Detroit.

15 Apr 2011

Acute high-fat diets can protect against heart attack

Approximately one million Americans suffer a heart attack each year of which some 400,000 attacks are fatal. A key cause of heart attacks is atherosclerosis, a process in which cholesterol builds up in the arteries and impedes the ability of the blood to flow to our most vital organ.

15 Apr 2011

Study shows neutralizing antibodies to C5a protein may prevent heart failure

New research published online in The FASEB Journal details research in rats and mice that offers hope for stopping the devastating, and often fatal, effects of sepsis in humans. In the study, University of Michigan researchers show how neutralizing the effects of a key protein fragment, called C5a, used by the immune system to attract white blood cells may ultimately prevent heart failure.

12 Apr 2011

Pfizer to support immatics' IMA901 Phase III trial in advanced renal cell carcinoma

immatics biotechnologies GmbH, a clinical-stage biopharmaceutical company developing advanced therapeutic vaccines that are active against cancer, today announced that Pfizer has agreed to support its pivotal Phase III trial with IMA901, its therapeutic cancer vaccine for advanced renal cell carcinoma.

11 Apr 2011

Louisville Chief of Cardiovascular Medicine earns APS' Walter B. Cannon Award

Heart failure affects roughly six million Americans, yet treatment consists of either a heart transplant or the insertion of mechanical devices that assist the heart. This is unacceptable to Roberto Bolli, MD, Chief of the Division of Cardiovascular Medicine at the University of Louisville in Louisville, Ky., which is why he is on a mission to make cardiac stem cell treatment an option for all who must cope with the limitations of a failing heart.

11 Apr 2011

Research Roundup: The cost of medical errors; 'Unreasonable rate increases'

Health Affairs: The $17.1 Billion Problem: The Annual Cost Of Measurable Medical Errors - "The estimated total cost of measurable medical errors in the United States was $17.1 billion in 2008, which was 0.72 percent of the $2.391 trillion spent on health care," write the authors of this study that used an "an actuarial approach to measure the frequency and costs of measurable U.S. medical errors, identified through medical claims data."

8 Apr 2011

Novation adds St. Jude Medical to portfolio of Cardiac Rhythm Management products

Novation, the leading health care supply contracting company, announced today the addition of St. Jude Medical (St. Paul, MN) to its portfolio of agreements for Cardiac Rhythm Management products.

8 Apr 2011

BioParadox's VitaKine PCT can serve as promising therapy for heart attack patients

BioParadox, Inc., a regenerative medicine company pioneering point-of-care biologic treatments for cardiovascular disease, today announced data supporting the use of VitaKine- Platelet Cell Therapy as a promising treatment for heart attack patients.

8 Apr 2011

Shionogi launches CUVPOSA for pediatric chronic severe drooling

Shionogi Inc., the U.S.-based group company of Shionogi & Co., Ltd., today announced the U.S. commercial availability of CUVPOSA™ (glycopyrrolate) oral solution, the first and only FDA-approved treatment to reduce chronic severe drooling in patients aged 3 to 16 with neurologic conditions associated with problem drooling, such as cerebral palsy.

7 Apr 2011

Alere achieves NCQA Accreditation for Nurse24 program

Alere Health, LLC announced today that it has achieved the National Committee for Quality Assurance Health Information Products Certification for Health Information Line.

7 Apr 2011

AstraZeneca receives FDA approval for vandetanib to treat medullary thyroid cancer

The U.S. Food and Drug Administration today approved vandetanib to treat adult patients with late-stage (metastatic) medullary thyroid cancer who are ineligible for surgery and who have disease that is growing or causing symptoms.

7 Apr 2011

ICD therapy can improve ischemic cardiomyopathy survival rates

Most patients with ischemic cardiomyopathy and dilated cardiomyopathy who have an implantable cardioverter-defibrillator now live more than seven years and those ICD patients with hereditary heart disease can live for decades, based on a scientific paper that will be presented at the American College of Cardiology Scientific Sessions in New Orleans, April 1-3.

6 Apr 2011

J&JPRD announces rivaroxaban Phase 3 trial results against venous thromboembolism

Johnson & Johnson Pharmaceutical Research & Development, L.L.C., today announced results from the MAGELLAN Phase 3 trial evaluating the investigational oral anticoagulant rivaroxaban for the prevention of venous thromboembolism in hospitalized patients with acute medical illnesses.

6 Apr 2011

Milliman Care Guidelines honors Sound Physicians with prestigious award

Sound Physicians, a leading hospitalist organization focused on driving improvements in quality, satisfaction and efficiency of inpatient healthcare delivery, today received the Doyle Award for Innovation and Leadership in Healthcare.

6 Apr 2011

Device to treat resistant hypertension lowers blood pressure by 33 points

A device designed to treat people with resistant hypertension helped lower blood pressure by 33 points, a substantial drop that would otherwise require patients to take an additional three or four drugs, on top of this subgroup's usual regimen of up to five drugs, to control their difficult-to-treat condition.

6 Apr 2011

MR patients treated with Abbott MitraClip system demonstrate clinical benefits of initial treatment at two years

Abbott today announced data from its EVEREST II (Endovascular Valve Edge-to-Edge REpair STudy) study showing that patients with significant mitral regurgitation (MR) treated with the company's investigational percutaneous catheter-based MitraClip® system continue to demonstrate the clinical benefits of initial treatment shown at one year out to two years, including improvements in heart function and reductions in symptoms.

5 Apr 2011

Milliman Care Guidelines presents Doyle Award to ADVANTAGE Health Solutions and Sound Physicians

Milliman Care Guidelines today presented its Doyle Award for Innovation and Leadership in Healthcare to ADVANTAGE Health Solutions, Inc.(SM) and to Sound Physicians. The awards were presented in ceremonies here at the Milliman Care Guidelines Client Forum.

5 Apr 2011

RE-LY trial results suggest Pradaxa capsule reduces risk of stroke in AF patients

Two new retrospective subanalyses of the RE-LY trial, involving Pradaxa capsules, suggested that the reduction in stroke risk achieved with PRADAXA 150mg over warfarin occurred irrespective of CHA2DS2-VASc risk score and the type of non-valvular atrial fibrillation.

5 Apr 2011

Heart Failure News and Research

Further Reading

New guidelines for cardiac specialists

Boehringer Ingelheim's dabigatran etexilate receives positive opinion from EMA committee

Patients with heart failure can benefit from left ventricular assist device

Acute high-fat diets can protect against heart attack

Study shows neutralizing antibodies to C5a protein may prevent heart failure

Pfizer to support immatics' IMA901 Phase III trial in advanced renal cell carcinoma

Louisville Chief of Cardiovascular Medicine earns APS' Walter B. Cannon Award

Research Roundup: The cost of medical errors; 'Unreasonable rate increases'

Novation adds St. Jude Medical to portfolio of Cardiac Rhythm Management products

BioParadox's VitaKine PCT can serve as promising therapy for heart attack patients

Shionogi launches CUVPOSA for pediatric chronic severe drooling

Alere achieves NCQA Accreditation for Nurse24 program

AstraZeneca receives FDA approval for vandetanib to treat medullary thyroid cancer

ICD therapy can improve ischemic cardiomyopathy survival rates

J&JPRD announces rivaroxaban Phase 3 trial results against venous thromboembolism

Milliman Care Guidelines honors Sound Physicians with prestigious award

Device to treat resistant hypertension lowers blood pressure by 33 points

MR patients treated with Abbott MitraClip system demonstrate clinical benefits of initial treatment at two years

Milliman Care Guidelines presents Doyle Award to ADVANTAGE Health Solutions and Sound Physicians

RE-LY trial results suggest Pradaxa capsule reduces risk of stroke in AF patients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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