Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Chinmax Medical Systems files complaint against Inverness Medical Beijing over distribution rights for Biosite products

On January 28, 2010, Chinmax Medical Systems, Inc., a leading distributor of clinical diagnostics in China, filed a civil complaint in the People's Court of Yangpu District, Shanghai against Inverness Medical Beijing Co. Ltd., a subsidiary of Inverness Medical Innovations, Inc..

8 Mar 2010

Glencoe Enterprise article highlights medical innovation and research enable people to live longer, healthier

An article in the Glencoe Enterprise recently highlighted the fact that medical innovation and research are enabling many people to live longer, healthier and more productive lives.

5 Mar 2010

Transcendental Meditation technique produces unique state of "restful alertness"

A new EEG study conducted on college students at American University found they could more highly activate the default mode network, a suggested natural "ground state" of the brain, during their practice of the Transcendental Meditation technique. This three-month randomized control study is published in a special issue of Cognitive Processing dedicated to the Neuroscience of Meditation and Consciousness, Volume 11, Number 1, February, 2010.

5 Mar 2010

TransMedics closes $36M financing round

TransMedics, Inc., a leading medical device company focusing on delivering the next standard of care for solid organ transplantation worldwide, announced today the closing of a $36 million financing round. The financing was lead by Foundation Capital and Kleiner Perkins Caufield & Byers (KPCB) and also included investments by Flagship Ventures and by several existing investors.

5 Mar 2010

Data evaluating safety, efficacy of STELARA and REMICADE in patients with plaque psoriasis to be presented

Data evaluating the efficacy and safety of STELARA™ (ustekinumab) and REMICADE® (infliximab) in patients with plaque psoriasis who had an inadequate response to Enbrel® (etanercept) will be presented at the 68th Annual Meeting of the American Academy of Dermatology (AAD) in Miami, Fla., from March 5-9, 2010.

5 Mar 2010

St. Jude Medical publishes clinical results of HOMEOSTASIS trial

St. Jude Medical, Inc. today announced publication of clinical results in the Hemodynamically Guided Home Self-Therapy in Severe Heart Failure Patients (HOMEOSTASIS) trial.

4 Mar 2010

Corning commercializes new Synthemax synthetic surface for supporting growth and differentiation of stem cells

Corning Incorporated today introduced the Corning® Synthemax™ surface, a novel synthetic surface that supports the growth and differentiation of stem cells. The surface is being commercialized as a result of Corning’s ongoing collaboration with Geron Corporation. This development enables researchers to take the next step toward scalable and cost-effective manufacturing of stem cells for potential therapies in the treatment of degenerative diseases.

4 Mar 2010

Beta blockers improve heart function; eliminate need for implantable cardiac devices

New Saint Louis University research has found that beta blockers, a class of drugs used to prevent the progression of heart failure and manage arrhythmias (irregular heart beat) and hypertension (high blood pressure), are underused in heart failure patients who receive implantable cardiac devices.

4 Mar 2010

Shock: Norepinephrine favored over dopamine

Physicians treating patients with shock should consider norepinephrine instead of dopamine as a tool for stabilizing blood pressure, according to an editorial in the March 4, 2010, issue of the New England Journal of Medicine (NEJM).

3 Mar 2010

Aggressive treatment of anemia with ESAs may lower risk of death for dialysis patients: Study

Aggressive treatment of anemia with intravenous iron and drugs known as erythropoiesis-stimulating agents (ESAs) may lower the risk of death for dialysis patients with severe anemia - but also may increase the risk of death among patients with milder anemia, a new study led by a University of North Carolina at Chapel Hill epidemiologist suggests.

3 Mar 2010

Baxter Healthcare's IIPV product recall of HomeChoice peritoneal dialysis cyclers classified as Class I recall

Baxter Healthcare Corporation announced today that the U.S. Food and Drug Administration (FDA) has classified Baxter’s recent Urgent Product Recall regarding Increased Intraperitoneal Volume (IIPV), or overfill of the abdominal cavity, associated with HomeChoice and HomeChoice Pro peritoneal dialysis cyclers as a Class I recall.

From Baxter International Inc. 3 Mar 2010

Geron highlights telomerase inhibitor's activity against cancer stem cells at AACR Special Conference

Geron Corporation today announced several presentations at the American Association for Cancer Research Special Conference on The Role of Telomeres and Telomerase in Cancer Research held in Fort Worth, TX between February 27th and March 1st.

3 Mar 2010

Critical follow-up evaluations provide opportunity to help physicians best evaluate their HF patients

Heart failure is by far the most prevalent chronic cardiac condition. Around 30 million people in Europe have heart failure and its incidence is still increasing: more cases are being identified, more people are living to an old age, and more are surviving a heart attack but with damage to the heart muscle.

2 Mar 2010

Use of at-home medical devices can help patients and physicians efficiently manage chronic conditions

The use of at-home medical devices to connect doctors and patients via the Internet can help patients and their physicians work more efficiently together to manage chronic conditions, according to research at Cleveland Clinic.

2 Mar 2010

Pre-clinical study of Cardio3 BioSciences' proprietary C-Cath catheter announced

Cardio3 BioSciences, a leading Belgian biotechnology company specialising in cell-based therapies for the treatment of cardiovascular diseases, announced today promising results in a pre-clinical study of its proprietary C-Cath(R) catheter which is under development to administer a range of bio-therapeutics to the heart. C-Cath is designed to take into account organ tissue structure and properties to maximize patients' safety, improve performance and increase user confidence during the injection procedure.

2 Mar 2010

Researchers develop sensitive measuring system for cGVHD

Researchers from The University of Texas M. D. Anderson Cancer Center have developed a new assessment tool to measure the severity of symptoms that can complicate stem cell transplantation. The tool assesses symptoms resulting from chronic graft-versus-host disease (cGVHD), and was presented with supporting research at the 2010 Bone and Marrow Transplant Tandem Meeting.

2 Mar 2010

Study shows ghrelin prevents acute liver damage, reduces oxidative stress and inflammation

Spanish researchers determined that rats treated with recombinant ghrelin displayed a reduction in liver fibrosis. Ghrelin, a stomach hormone, reduced the amount of fibrogenic cells by 25% in the treated rodents. Research further showed ghrelin prevented acute liver damage and reduced oxidative stress and inflammation in the animal models.

1 Mar 2010

Health Policy Research Roundup: Length of hospital stays, analyses of Obama's reform proposals

Archives Of Internal Medicine: Hospital Cost Of Care, Quality Of Care, And Readmission Rates - This study compares patients treated for pneumonia and congestive heart failure (CHF) and finds that high-cost hospitals don't always deliver better care. The researchers, who based their analysis on the data from 3,146 hospitals in the 2004 to 2006 Medicare Provider Analysis and Review (MedPAR), report that "risk-adjusted costs of care for CHF and pneumonia varied widely between hospitals, although hospital cost-of-care patterns seemed stable over time and correlated across conditions."

27 Feb 2010

Medical innovation and research: A real boon for American patients to live longer, healthier

An article in the Suislaw News recently highlighted the fact that medical innovation and research are enabling many people to live longer, healthier and more productive lives.

26 Feb 2010

Regulus Therapeutics, GSK announce new collaboration on microRNA therapeutics targeting microRNA-122

Regulus Therapeutics Inc. today announced the establishment of a new collaboration with GlaxoSmithKline (GSK) to develop and commercialize microRNA therapeutics targeting microRNA-122 in all fields with Hepatitis C Viral infection (HCV) as the lead indication. Under the terms of the new collaboration, Regulus will receive additional upfront and early-stage milestone payments with the potential to earn more than $150 million in miR-122-related combined payments, and tiered royalties up to double digits on worldwide sales of products.

25 Feb 2010

Heart Failure News and Research

Further Reading

Chinmax Medical Systems files complaint against Inverness Medical Beijing over distribution rights for Biosite products

Glencoe Enterprise article highlights medical innovation and research enable people to live longer, healthier

Transcendental Meditation technique produces unique state of "restful alertness"

TransMedics closes $36M financing round

Data evaluating safety, efficacy of STELARA and REMICADE in patients with plaque psoriasis to be presented

St. Jude Medical publishes clinical results of HOMEOSTASIS trial

Corning commercializes new Synthemax synthetic surface for supporting growth and differentiation of stem cells

Beta blockers improve heart function; eliminate need for implantable cardiac devices

Shock: Norepinephrine favored over dopamine

Aggressive treatment of anemia with ESAs may lower risk of death for dialysis patients: Study

Baxter Healthcare's IIPV product recall of HomeChoice peritoneal dialysis cyclers classified as Class I recall

Geron highlights telomerase inhibitor's activity against cancer stem cells at AACR Special Conference

Critical follow-up evaluations provide opportunity to help physicians best evaluate their HF patients

Use of at-home medical devices can help patients and physicians efficiently manage chronic conditions

Pre-clinical study of Cardio3 BioSciences' proprietary C-Cath catheter announced

Researchers develop sensitive measuring system for cGVHD

Study shows ghrelin prevents acute liver damage, reduces oxidative stress and inflammation

Health Policy Research Roundup: Length of hospital stays, analyses of Obama's reform proposals

Medical innovation and research: A real boon for American patients to live longer, healthier

Regulus Therapeutics, GSK announce new collaboration on microRNA therapeutics targeting microRNA-122

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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