Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Discovery could lead to new drug targets for heart disease

Mice with glowing green hearts have yielded the latest clue in the search for molecules involved in structural heart disease. Vanderbilt University Medical Center investigators found that blocking the activity of a single protein, called CaM kinase, in the mouse heart protects against the damaging effects of a heart attack.

30 Mar 2005

Important link between kidney damage and cardiac problems

Scientists have identified an important link between kidney damage and cardiac problems, creating new possibilities for treating the primary cause of death in kidney disease patients.

29 Mar 2005

Herceptin - more powerful treatment for patients with HER-2-positive breast cancer

A new use of the drug Herceptin appears to offer a much more powerful treatment advantage than expected for patients with HER-2-positive breast cancer, say researchers at The University of Texas M. D. Anderson Cancer Center.

29 Mar 2005

Doctors raise concern about heart drug Nesiritide

Doctors raise concern about heart drug. The heart drug Nesiritide (Natrecor) is an FDA-approved drug for the treatment of decompensated heart failure, the most common reason for hospitalization for those over 65 years of age.

22 Mar 2005

Ongoing specialist care can improve heart attack survival

When a good network of care involving access to specialists and family physicians is established, it can significantly improve the number of lives saved from heart disease, especially in rural areas, according to a University of Alberta two-year study.

16 Mar 2005

Questions about validity of HOPE TOO vitamin E study

A study published in the March 16 issue of Journal of the American Medical Association (JAMA) suggesting that a "daily-dose" of vitamin E (400 international units) among high-risk (chronically ill) cardiovascular patient populations is associated with a greater risk of heart failure is being challenged by leading health researchers around the country who claim the study lacks the adequate research and controlled sampling audience to justify this conclusion.

16 Mar 2005

More research on Vitamin E surprises scientists

50 years of research into the supposed benefits of taking vitamin E has extolled its antioxidant potential to offer a variety of potential health benefits, including reducing the risk of Alzheimer's, cancer and heart disease.

15 Mar 2005

Vitamin E may increase heart attack risk - does not prevent cancer

A study by Canadian researchers Eva Lonn, M.D., of the Population Health Research Institute and McMaster University, Hamilton Health Sciences Corporation, Hamilton, Ontario, Canada, and colleagues, has found from examining experimental and epidemiological data, that patients who took vitamin E supplements for 7 years did not significantly reduce their risk of cancer or cardiovascular events and some in fact had an increased risk of heart failure.

15 Mar 2005

Study indicates that vitamin E does not prevent cancer

Patients who took vitamin E supplements for about 7 years did not have their risk of cancer or cardiovascular events significantly reduced, and in fact some had an increased risk of heart failure, according to a study in the March 16 issue of JAMA.

15 Mar 2005

Vasogen granted European patent in chronic heart failure

Vasogen today announced that it has been granted a European patent covering the use of its Celacade technology for the treatment of chronic heart failure, and has completed the registration procedure to bring it fully into force in all the major countries of Europe including the U.K., France, Germany, Spain, Italy, and Sweden.

15 Mar 2005

Only one-third of cardiologists believe racial and ethnic disparities in care occur often in the United States

Only one-third of cardiologists surveyed believe racial and ethnic disparities in care occur often in the United States despite extensive documentation of the problem, according to a survey published in a special disparities issue of Circulation: Journal of the American Heart Association.

15 Mar 2005

Disparities in health care are pervasive in America

Disparities in health care are pervasive in America. These disparities adversely impact the cardiovascular health of Americans, especially African Americans, Hispanics, poor and uneducated people, according to a report in a special disparities themed issue of Circulation: Journal of the American Heart Association.

15 Mar 2005

Blacks less likely to get expensive, newer heart treatments

Blacks who suffer the most common type of cardiac ischemia – non-ST-elevation acute coronary syndrome – are less likely than whites to receive expensive or newer evidence-based treatments, according to a report in a special disparities themed issue of Circulation: Journal of the American Heart Association.

15 Mar 2005

Nature of electrical abnormalities occurring during the development of heart failure

A Johns Hopkins undergraduate student has contributed to new research showing that electrical changes in the heart leading to heart failure can occur long before a patient exhibits any clinical symptoms.

8 Mar 2005

Adiponectin may be helpful in finding treatments for Progeria

In a study published in the March issue of The Journal of Pediatrics, researchers found that decreased levels of HDL cholesterol, or "good" cholesterol, may contribute to premature heart disease in children with Hutchinson-Gilford Progeria Syndrome, or Progeria.

8 Mar 2005

Keep laughing, its doing you more good than you realise

Dr. Michael Miller of the University of Maryland School of Medicine in Baltimore showed two movies, one humorous, one stressful, to 20 healthy volunteers and tested the function of their blood vessels.

7 Mar 2005

Beta-blockers can benefit patients with certain serious heart problems such as diastolic heart failure

Beta-blockers, medications that block the action of certain hormones on the heart, can benefit patients with certain serious heart problems such as diastolic heart failure, according to cardiologists at the Keck School of Medicine of the University of Southern California and Loma Linda University Medical Center.

7 Mar 2005

Implanted devices are giving cardiologists a new view of subtle changes in a key measurement of heart health

Implanted devices intended to optimize the cardiac function of patients with heart failure have provided new insights into which patients might be at higher risk of dying suddenly from their disease, according to researchers at Duke University Medical Center.

7 Mar 2005

Serum sodium level is a major predictor of a poor prognosis for heart failure patients

Research presented today at the American College of Cardiology's Scientific Sessions in Orlando pinpoints a major marker of a poor prognosis for heart failure, hyponatremia, or a lower than normal concentration of serum or blood sodium.

7 Mar 2005

FDA issues information on the risks and benefits of Crestor

The U.S. Food and Drug Administration (FDA), today issued public health advice, patient information, and professional healthcare information on the risks and benefits of Crestor (Rosuvastatin calcium), a cholesterol-lowering drug.

2 Mar 2005

Heart Failure News and Research

Further Reading

Discovery could lead to new drug targets for heart disease

Important link between kidney damage and cardiac problems

Herceptin - more powerful treatment for patients with HER-2-positive breast cancer

Doctors raise concern about heart drug Nesiritide

Ongoing specialist care can improve heart attack survival

Questions about validity of HOPE TOO vitamin E study

More research on Vitamin E surprises scientists

Vitamin E may increase heart attack risk - does not prevent cancer

Study indicates that vitamin E does not prevent cancer

Vasogen granted European patent in chronic heart failure

Only one-third of cardiologists believe racial and ethnic disparities in care occur often in the United States

Disparities in health care are pervasive in America

Blacks less likely to get expensive, newer heart treatments

Nature of electrical abnormalities occurring during the development of heart failure

Adiponectin may be helpful in finding treatments for Progeria

Keep laughing, its doing you more good than you realise

Beta-blockers can benefit patients with certain serious heart problems such as diastolic heart failure

Implanted devices are giving cardiologists a new view of subtle changes in a key measurement of heart health

Serum sodium level is a major predictor of a poor prognosis for heart failure patients

FDA issues information on the risks and benefits of Crestor

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