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DNA “webs” shown to promote metastasis in ovarian cancer

Researchers have found that neutrophils cast DNA “webs” that aid the spread of ovarian cancer cells to new tissues (a process known as metastasis).

19 Dec 2018

Speed and error rate of DNA synthesis influenced by DNA structure

The speed and error rate of DNA synthesis is influenced by the three-dimensional structure of the DNA. Using "third-generation" genome-wide DNA sequencing data, a team of researchers from Penn State and the Czech Academy of Sciences showed that sequences with the potential to form unusual DNA conformations, which are frequently associated with cancer and neurological diseases, can in fact slow down or speed up the DNA synthesis process and cause more or fewer sequencing errors.

14 Nov 2018

First bifacial molecule can invade double-stranded DNA or RNA

Carnegie Mellon University researchers have developed a synthetic molecule that can recognize and bind to double-stranded DNA or RNA under normal physiological conditions. The molecule could provide a new platform for developing methods for the diagnosis and treatment of genetic conditions.

13 Nov 2018

NIH-funded genome centers to speed up breakthroughs in precision medicine

The All of Us Research Program awarded funds totaling $28.6 million to establish three genome centers around the country. These centers will begin to generate genomic data from biosamples contributed by the program's participants.

26 Sep 2018

Study reveals how dangerous bacterium shares its genetic information

Bacteria are very sneaky in their efforts to develop resistance to antibiotics. Some strains of bacteria package up the genetic instructions for how they defend themselves and cause disease, and pass this information on to neighbouring, naïve, bacteria - essentially gifting their colleagues with the defences they need to survive against our medical armoury of antibiotics.

14 Sep 2018

MyVytalics launches new personal app focusing on genes related to sleep patterns, nutrition

MyVytalics, a privately held company, today announced the release of MySleepInsights, a personal genomics app focusing on genes associated with sleep patterns and nutrition.

10 Sep 2018

Hsp90 protein appears to stimulate exosome release

Researchers from the Verstreken lab have identified a completely novel function for Hsp90, one of the most common and most studied proteins in our body.

7 Sep 2018

Researchers discover brain cells that express sense of time within experiences, memories

Researchers at the Kavli Institute for Systems Neuroscience in Trondheim, Norway have discovered a network of brain cells that express our sense of timewithin experiences and memories.

30 Aug 2018

Socio-economic position associated with pregnant women's exposure to environmental hazards

Socio-economic position determines the environmental hazards--such as air pollution and noise--that pregnant women are exposed to in urban areas, although the nature of the association varies from city to city.

16 Aug 2018

Winners of Promega's first Helix Sustainability awards announced

Promega UK, based on the University of Southampton Science Park in Hampshire, has announced the winners of its first Helix Sustainability award.

From Promega Corporation 27 Jul 2018

New protein complex may explain why patients develop resistance to novel anti-cancer drugs

A team of researchers at the University of Cambridge has identified a protein complex that might explain why some cancer patients treated with the revolutionary new anti-cancer drugs known as PARP inhibitors develop resistance to their medication.

25 Jul 2018

Researchers discover why CRISPR gene editing sometimes fails

A study has explained for the first time why the CRISPR gene editing tool fails to work in 15% cases, and has suggested methods to prevent this.

11 Jul 2018

Researchers reveal why CRISPR gene editing sometimes fails to work

Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient.

11 Jul 2018

New biosensor chip detects single nucleotide polymorphism in real time with high sensitivity

A team led by the University of California San Diego has developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism and send the results in real time to a smartphone, computer, or other electronic device.

10 Jul 2018

Study finds more information about how gene linked to ASD affects the brain

New preclinical research shows a gene already linked to a subset of people with autism spectrum disorder is critical to healthy neuronal connections in the developing brain, and its loss can harm those connections to help fuel the complex developmental condition.

18 Jun 2018

IU researchers observe bacteria's 'DNA uptake' process

Indiana University scientists have made the first direct observation of a key step in the process that bacteria use to rapidly evolve new traits, including antibiotic resistance.

12 Jun 2018

Havard University grants license to Beam Therapeutics to develop new base editing technology

Harvard University has granted a worldwide license to Beam Therapeutics, Inc., to develop and commercialize a suite of revolutionary DNA base editing technologies for the treatment of human disease.

14 May 2018

CMS approves national reimbursement coverage for CardiAMP Chronic Myocardial Ischemia Trial

BioCardia, Inc., a leader in the development of comprehensive solutions for cardiovascular regenerative therapies, today announced that the Centers for Medicare and Medicaid Services has approved national reimbursement coverage for the CardiAMP Chronic Myocardial Ischemia Trial.

10 May 2018

Scientists use X-ray laser to gain insights into structure of Alzheimer's proteins

A new experimental method permits the X-ray analysis of amyloids, a class of large, filamentous biomolecules which are an important hallmark of diseases such as Alzheimer's and Parkinson's.

9 May 2018

Sylentis presents clinical study results of new treatment for dry eye syndrome

Sylentis, Pharmaceutical Company belonging to the PharmaMar Group, has presented results from the clinical studies carried out with tivanisiran for the treatment of dry eye syndrome and that has enabled the start-up of the Phase III "Helix" clinical trial.

3 May 2018