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“Chemical surgery” on embryos to free them of a gene causing thalassemia

A team of Chinese researchers have for the first time “mended” defective embryos using chemical surgery to free them of a faulty gene that leads to beta thalassemia. Until now this defect was found to be incorrigible caused due to a single misspelling in the DNA code. Beta thalassemia is a dreaded blood disorder wherein the child is unable to make healthy blood needing blood transfusions on a regular basis. The study was published this week in the journal Protein and Cell.

2 Oct 2017

New findings could help doctors gain insight on miscarriage

The major structures of a baby's heart form in just four days, according to new research using the latest imaging techniques.

30 Sep 2017

New 3D protein structure provides detailed look into how brain cells communicate quickly

An intricate new three-dimensional protein structure is providing a detailed look into how brain cells communicate rapidly.

13 Sep 2017

Old lab technique helps researchers better understand circular DNA

A 50-year-old lab technique is helping researchers better understand circular DNA, a lesser-known and poorly understood cousin of the linear version commonly associated with life's genetic blueprint.

12 Sep 2017

Potential rare gene mutation could act as predictor for schizophrenia and autism

Huntington's disease, cystic fibrosis, and muscular dystrophy are all diseases that can be traced to a single mutation. Diagnosis in asymptomatic patient for these diseases is relatively easy - You have the mutation? Then you are at risk. Complex diseases, on the other hand, do not have a clear mutational footprint.

30 Aug 2017

Scientists uncover stem cell response to prolonged irradiation

Researchers from several Russian institutes, including MIPT, have found out how prolonged exposure to ionizing radiation affects human stem cells.

24 Aug 2017

Vanderbilt researchers unravel how bacterial toxin prevents DNA replication

One of the most potent toxins known acts by welding the two strands of the famous double helix together in a unique fashion which foils the standard repair mechanisms cells use to protect their DNA.

2 Aug 2017

New imaging approach reveals dynamic and structural interactions of DNA in cell's nucleus

Sixty-four years ago, James Watson and Francis Crick described the now-iconic double helix structure of DNA.

29 Jul 2017

New technology could help patients requiring stem cell therapies for Parkinson's, stroke, other diseases

A groundbreaking advancement in materials from Northwestern University could potentially help patients requiring stem cell therapies for spinal cord injuries, stroke, Parkinson's disease, Alzheimer's disease, arthritic joints or any other condition requiring tissue regeneration, according to a new study.

10 Jul 2017

Alzheimer’s disease specific brain deposits photographed for the first time in vivid detail

Scientists from the Britain's Medical Research Council Laboratory of Molecular Biology have for the first time, clearly pictured what the deposits typically seen in a person with Alzheimer’s disease look like. This is a breakthrough in neurodegenerative diseases. The latest study showing the structure of tau protein was published in the journal Nature.

5 Jul 2017

Scientists find new clues to how RSV causes disease

By age 2, most children have been infected with respiratory syncytial virus (RSV), which usually causes only mild cold symptoms. But people with weakened immune systems, such as infants and the elderly, can face serious complications, including pneumonia and -- in some cases -- death.

30 Jun 2017

Researchers discover broad role for DNA-cutting enzyme in driving abnormal genetic rearrangements

Researchers studying a DNA-cutting enzyme with a crucial role in regulating the structure of genes have discovered a broad role for its cutting activity in driving abnormal genetic rearrangements called translocations that cause cancer, including leukemias and solid tumors.

16 Jun 2017

Scripps scientists make important advance in HIV vaccine design

Scientists at The Scripps Research Institute (TSRI) have made another important advance in HIV vaccine design. The development was possible thanks to previous studies at TSRI showing the structures of a protein on HIV’s surface, called the envelope glycoprotein. The scientists used these structures to design a mimic of the viral protein from a different HIV subtype, subtype C, which is responsible for the majority of infections worldwide.

29 May 2017

Stem cell therapy using Helix transendocardial delivery system provides better results, study shows

BioCardia, Inc. today announced publication of a study in the International Heart Journal. According to the study, delivery of stem cell therapy to the heart using the Helix transendocardial delivery system results in superior cell delivery than either percutaneous intra-coronary infusion or direct injection in an open chest procedure.

24 May 2017

Genomic Analysis Technologies: Past, Present and Future

In this interview, Jay Flatley, Executive Chairman of Illumina, gives an introduction to Illumina and the next generation genomics tools they provide.

From Pittcon 10 Apr 2017

New finding on key protein opens door to potential therapies for chronic illnesses

Scientists have determined unexpected characteristics of a key protein linked to blood pressure control and to nerve growth, pain control and heart tissue regeneration. The findings, published April 5 online in the journal Nature, opens doors to potential new therapies to control cardiovascular disease and pain.

6 Apr 2017

Helix News and Research

“Chemical surgery” on embryos to free them of a gene causing thalassemia

New findings could help doctors gain insight on miscarriage

New 3D protein structure provides detailed look into how brain cells communicate quickly

Old lab technique helps researchers better understand circular DNA

Potential rare gene mutation could act as predictor for schizophrenia and autism

Scientists uncover stem cell response to prolonged irradiation

Vanderbilt researchers unravel how bacterial toxin prevents DNA replication

New imaging approach reveals dynamic and structural interactions of DNA in cell's nucleus

New technology could help patients requiring stem cell therapies for Parkinson's, stroke, other diseases

Alzheimer’s disease specific brain deposits photographed for the first time in vivid detail

Scientists find new clues to how RSV causes disease

Researchers discover broad role for DNA-cutting enzyme in driving abnormal genetic rearrangements

Scripps scientists make important advance in HIV vaccine design

Stem cell therapy using Helix transendocardial delivery system provides better results, study shows

Genomic Analysis Technologies: Past, Present and Future

New finding on key protein opens door to potential therapies for chronic illnesses

Kent state researchers use DNA origami to create ‘nano cage’ for deeper study of cancer cell growth

High-resolution images of protein complex performing first step in genome-replication dance captured

LJI researchers unravel molecular underpinnings of exhausted T cells

ASU-led engineers develop new DNA switch to control flow of electrons within atomic-sized molecule

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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