Hemoglobin News and Research

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Combined aerobic and resistance training best for people with diabetes

In a new randomized controlled trial, both aerobic and resistance exercise improved glycemic/blood sugar control in people with type 2 diabetes.

18 Sep 2007

HIV patients with declining platelet counts appear to be at increased risk for HIV-associated dementia

Therapies leading to longer life for HIV patients have paradoxically increased the prevalence of this condition. Identifying biological markers for the development of HIV–associated dementia is critical both for diagnosing the disorder and for understanding its underlying mechanisms.

11 Sep 2007

Discovery of novel cause of iron overload in patients with thalassemia

According to the study, thalassemia patients overproduce a protein called GDF15, which suppresses the production of a liver protein, hepcidin, which in turn leads to an increase in the uptake of dietary iron in the gut.

30 Aug 2007

New technology for keeping liver cells alive inside bioartificial liver-assist devices

Such devices enable people who are suffering from acute liver failure to survive while their own liver cells regenerate, or until they receive a liver transplant. The person's blood or plasma circulates through the device. Inside, living cells -- usually pig or human liver cells -- perform normal liver functions.

24 Aug 2007

New techniques for measuring blood volume

The July issue of The American Journal of Medical Sciences presents a special symposium on the measurement and clinical implications of blood volume and its measurement.

16 Aug 2007

New research may lead to future gene therapies for patients with sickle cell anemia and beta-thalassemia

Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells.

7 Aug 2007

Jump in cancer-related clots

Blood clots are increasingly common in cancer patients, but University of Rochester Medical Center researchers have created a novel risk model that can predict, with 98 percent certainty, which patients will not get a blood clot.

3 Aug 2007

Discovery of molecular pathway that detects and eliminates defective messenger RNAs from red blood cells

Other such pathways - known as surveillance pathways - operate in a more general way, in many cell types. Knowing how this specific surveillance system works can help researchers better understand hereditary diseases, in this case, thalassemia, a form of anemia, which is the most common genetic disorder worldwide.

3 Aug 2007

Hemoglobin-based oxygen carrier shows promise as treatment for sickle cell disease

Studies in mice suggest that a red blood cell substitute based on human hemoglobin could be a promising new treatment for sickle cell disease in humans.

24 Jul 2007

High-definition telemedicine

As a surgeon performs a minimally invasive procedure at Cedars-Sinai Medical Center in Los Angeles, surgeons observing in Boston or Mexico City or London will notice a remarkable improvement in clarity, compared to the view they would have had in the past.

18 Jul 2007

Analysis of diabetes drugs

Most oral medications prescribed for type 2 diabetes are similarly effective for reducing blood glucose, but the drug metformin is less likely to cause weight gain and may be more likely than other treatments to decrease so-called bad cholesterol, according to a report funded by HHS Agency for Healthcare Research and Quality.

17 Jul 2007

New method to estimate sickle cell disease severity

Researchers from Boston University School of Medicine (BUSM) and Boston University School of Public Health (BUSPH) have developed a method to estimate sickle cell disease severity and predict the risk of death in people with this disease.

12 Jul 2007

Functional data analysis in renal anemia

Anemia is one of the most frequent complications of hemodialysis, and its correction is an important factor in restoring a tolerable quality of life to dialysis-dependent patients.

12 Jul 2007

Alogliptin for type 2 diabetes shows promise in early trial

Alogliptin, a highly selective dipeptidyl peptidase-IV (DPP-4) inhibitor under investigation for the treatment of type 2 diabetes, demonstrated efficacy in reducing glucose levels throughout the day, in an early phase clinical study.

26 Jun 2007

Solvay Pharmaceuticals submits supplemental NDA for AndroGel

Solvay Pharmaceuticals, Inc., has announced that it submitted a supplemental New Drug Application (sNDA) for AndroGel (testosterone gel) 1% CIII to the U.S. Food and Drug Administration (FDA) for treatment in male adolescents ages 13-17 years old with primary or secondary hypogonadism.

17 Jun 2007

Researchers create first 3-D optical images of human breast cancer in patients based on tissue fluorescence

Fluorescence diffuse optical tomography, or FDOT, relies on the presence of fluorophore molecules in tissue that re-radiate fluorescent light after illumination by excitation light of a different color.

14 Jun 2007

New understanding of anti-malarial drug resistance

Researchers at Georgetown University Medical Center say they are moving closer to understanding why the most lethal form of human malaria has become resistant to drug treatment in the past three decades.

8 Jun 2007

Diagnosing skin cancers with laser-based system

In an early step toward nonsurgical screening for malignant skin cancers, Duke University chemists have demonstrated a laser-based system that can capture three-dimensional images of the chemical and structural changes under way beneath the surface of human skin.

5 Jun 2007

Quality improvement effort pays off in diabetes care

Spending money to improve diabetes care at federally qualified community health centers is a sound investment, according to one of the first studies to examine the clinical and economic impact of quality improvement on diabetes care.

18 May 2007