Hemoglobin News and Research

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HIV drug combo Trimethoprim-sulfamethoxazole highly effective at preventing malaria

A drug combination used to prevent pneumonia and opportunistic bacterial infection in persons with HIV/AIDS has unexpectedly been found to be highly effective at preventing malaria, according to a study published in the November 15 issue of The Journal of Infectious Diseases, now available online.

18 Oct 2005

Paying clinicians to reach a common, fixed performance target may produce little gain in overall quality

...and may largely reward those with higher performance at baseline, according to a study in the October 12 issue of JAMA: The Journal of the American Medical Association.

11 Oct 2005

Researchers reveal basis for hereditary coproporphyria

A research team led by scientists at The University of Texas Medical School at Houston has determined the structure of an enzyme that when defective causes an inherited disease that afflicts sufferers with severe abdominal pain, psychiatric symptoms, skin fragility, and light sensitivity.

9 Oct 2005

Protein secreted by the dog hookworm may advance vaccine development in humans

A paper published in this week's PLoS Medicine shows that vaccination against a protein secreted by the dog hookworm can protect against blood loss and anaemia caused by the same hookworm in dogs.

4 Oct 2005

Lack of oxygen in body tissues creates a defect of red blood cells that further exacerbates the condition by constricting blood vessels in the lung

What's more, the team demonstrated through studies in people and animals that inhalation of a 'souped up' form of nitric oxide, which targets red blood cells, reverses the blood abnormality to restore normal lung pressure.

3 Oct 2005

Combining optical tomography with standard ultrasound imaging can help distinguish early-stage breast cancer

A new study shows that combining a technology called optical tomography with standard ultrasound imaging can help distinguish early-stage breast cancer from non-cancerous lesions--and potentially reduce the number of breast biopsies performed. The study appears in the October issue of the journal Radiology.

27 Sep 2005

Adult sickle cell drug hydroxyurea proves effective in young children

A drug used for the treatment of sickle cell anemia in adults has now been shown to cause significant improvements in very young children with the disorder.

20 Sep 2005

Lowering blood sugar levels could reduce the risk of coronary heart disease

Lowering blood sugar levels could reduce the risk of coronary heart disease in both diabetics and non-diabetics, according to researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions.

19 Sep 2005

Can a new combination treatment prevent a secondary stroke in children with sickle cell anemia?

St. Jude Children’s Research Hospital will lead a national Phase III clinical trial to investigate whether a new combination treatment can prevent a secondary stroke in children with sickle cell anemia (SCA) and eliminate the need for nightly injections with a drug that reduces iron overload in these patients.

1 Sep 2005

Ways to avoid hazards of heart bypass under study

The heart-lung bypass machine that stills the heart while surgeons bypass an adult’s clogged arteries or repair a baby’s malformed heart can also trigger a potentially deadly inflammatory response.

28 Aug 2005

Unique blood test detects iron deficiency in infants earlier

A unique blood test detects iron deficiency in infants earlier and more accurately than the commonly used hemoglobin screening test, according to a study in the August 24/31 issue of the Journal of the American Medical Association.

23 Aug 2005

Defects in newly discovered pathway may be an overlooked cause of anemia

Researchers studying zebrafish that die from anemia have discovered a new pathway for the synthesis of heme, the deep red, iron-containing molecule that is a component of hemoglobin and myoglobin.

18 Aug 2005

Low hemoglobin levels are a predictor of increased risk of death among heart failure patients

Hemoglobin (Hgb) is the major substance in red blood cells, and its level indicates the blood's ability to carry oxygen throughout the body. Studies have shown that low hemoglobin, which may result in anemia, is more common among patients with heart failure than it is among people in the general population.

17 Aug 2005

Oral medications may control symptoms of Type II diabetes in children just as well as insulin injections

According to the medical records of 26 children diagnosed with the disease, oral medications reduced levels of a compound in the blood called hemoglobin A1C by an average of 2 percentage points.

15 Aug 2005

New insight into how protein E75 may control circadian rhythms and metabolic processes

University of Toronto researchers have gained new insight into how a specific protein may control circadian rhythms and metabolic processes, which has implications for treating cholesterol-related diseases.

28 Jul 2005

Quality of care may vary in association with the characteristics of individual physicians and their practices

Certain physician characteristics and practice-setting characteristics are associated with Medicare beneficiaries receiving routine preventive services below the national goals, according to a study in the July 27 issue of JAMA: The Journal of the American Medical Association.

27 Jul 2005

Chromium picolinate significantly reduces weight gain associated with common antidiabetic medication

...according to a study released today. Researchers at the Pennington Biomedical Research Center (PBRC), who conducted the study, also found that chromium significantly improved blood sugar control and insulin sensitivity.

16 Jun 2005

Hydroxyurea may prevent complications such as organ damage and stunted growth in treatment of sickle cell disease

Treating babies who have sickle cell disease (SCD) with oral liquid hydroxyurea appears to prevent the onset of long-term complications triggered by this disease, according to results of a preliminary study by investigators at St. Jude Children's Research Hospital.