Hepatology News and Research

RSS

Hepatology is the branch of medicine that incorporates study of liver, gallbladder, biliary tree and pancreas as well as management of their disorders.

Scientists provide evidence of the positive effects of alcohol abstinence in advanced liver cirrhosis

Complete abstinence from alcohol is considered a cornerstone in the treatment of patients with alcohol-related liver disease. It has not yet been sufficiently researched whether this measure can still improve the prognosis even in the case of advanced liver cirrhosis.

14 Dec 2022

New approach enables robust intestinal mini-organs to be grown more easily in the lab

Growing human body parts in the lab is a common trope of horror movies and sci-fi books. But growing miniature organ-like tissues in the lab is already within our reach.

6 Dec 2022

Harmful gut bacteria co-opt a genetic susceptibility to trigger Crohn’s disease

Changes in a single gene open the door for harmful gut bacteria to set off the inflammation that drives Crohn’s disease, according to a new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Dec 2022

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

1 Dec 2022

Acute COVID-19 infection disrupts a healthy balance between good and bad gut microbes

In an intensive look at the effects of the virus causing COVID-19 on patients' microbiome – the collection of microorganisms that live in and on the human body – Rutgers scientists found that acute infection disrupts a healthy balance between good and bad microbes in the gut, especially with antibiotic treatment.

28 Nov 2022

Study: Nearly 1 in 7 Americans regularly experience bloating issues

Nearly 1 in 7 Americans experience bloating on a weekly basis, and most aren't seeking professional care for it, according to a new study led by Cedars-Sinai investigators.

24 Nov 2022

New AI blood testing technology detects more than 80% of liver cancers

A novel artificial intelligence blood testing technology developed and used by Johns Hopkins Kimmel Cancer Center researchers to successfully detect lung cancer in a 2021 study has now detected more than 80% of liver cancers in a new study of 724 people.

20 Nov 2022

Study determines the diagnostic utility of liver stiffness measurement

Even after chronic hepatitis C has been cured, portal hypertension remains the major factor driving the development of complications in advanced liver disease. In cooperation with researchers from Spain, a research team led by Georg Semmler and Mattias Mandorfer from the Division of Gastroenterology and Hepatology at MedUni Vienna's Department of Medicine III showed that the non-invasive tests explored in their earlier studies accurately estimate the probability of sequelae.

3 Nov 2022

Study highlights the importance of early screening of first-degree relatives of patients with NAFLD

Approximately one-fourth of the general population worldwide has nonalcoholic fatty liver disease, known as NAFLD, an umbrella term for a range of liver conditions affecting people who drink little to no alcohol. NAFLD can lead to cirrhosis, liver cancer and liver failure.

1 Nov 2022

Third dose of COVID-19 mRNA vaccine offers cirrhosis patients strong protection against the virus

Cirrhosis of the liver is associated with decreased responsiveness to many vaccines, including those that protect against COVID-19.

27 Oct 2022

Diet plays an important role in the success of immunotherapy

Eating a Mediterranean diet, rich in fiber, mono-unsaturated fatty acids and polyphenols, has been associated with improved immunotherapy response rates and progression-free survival in advanced melanoma patients, a new study presented today at UEG Week 2022 has found.

10 Oct 2022

Global burden of liver cancer could rise by more than 55% by 2040, analysis reveals

A new analysis reveals that primary liver cancer was among the top three causes of cancer death in 46 countries in 2020 and the number of people diagnosed with or dying from primary liver cancer per year could rise by more than 55% by 2040.

5 Oct 2022

Study shows the important role of hepatocyte adenosine kinase in NAFLD progression

A study led by Texas A&M AgriLife Research provides compelling evidence of the important role of hepatocyte adenosine kinase in the progression of nonalcoholic fatty liver disease, NAFLD.

5 Oct 2022

Fungal involvement in tumors may drive worse cancer outcomes

The presence of some fungal species in tumors predicts-;and may even help drive-;worse cancer outcomes, according to a study from Weill Cornell Medicine and Duke University researchers.

3 Oct 2022

Orally ingestible robotic drug delivery device overcomes barriers of the gastrointestinal environment

Oral drug delivery is the most common and cost-effective way to deliver a treatment. But drugs must make it through the harsh, acidic environment of the stomach, resist degradation by enzymes, penetrate the barrier posed by the mucus of the small intestine and overcome many other obstacles before they can be absorbed.

28 Sep 2022

Study offers support for increasing the use of living donor liver transplantation in Western countries

Demand for donor livers for transplant patients outstrips supply with over 15% of waitlist patients dying after a year.

26 Sep 2022

Designing a new treatment to treat migraine effectively

In this interview, we speak to Mudra Kapoor, Vice President of Global Medical Affairs for Neuroscience at AbbVie, about atogepant, their new treatment option for migraine.

From AbbVie 26 Sep 2022

Study may lead to a new way for treating children with eosinophilic esophagitis

A groundbreaking study from Ann & Robert H. Lurie Children's Hospital of Chicago determined the threshold for a new measure of early scarring in the esophagus of children with eosinophilic esophagitis (EoE), which allows immediate intervention during endoscopy to halt further damage and prevent food from getting stuck in the esophagus (feeding tube) of kids with this condition.

16 Sep 2022

Most people prefer fecal immunochemical test rather than a colonoscopy, study says

Three-quarters of people prefer to do a fecal immunochemical test (FIT) rather than a colonoscopy for their regular colorectal cancer screening, according to a new Cedars-Sinai study.

12 Sep 2022

New cold perfusion approach to isolate hepatic stellate cells from fatty liver-associated tumors

Obesity can give rise to a variety of health concerns. Nonalcoholic steatohepatitis (NASH)-; a type of fatty liver disease that might progress to cancer-; is particularly prevalent among obese people.