Hepatology News and Research

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Hepatology is the branch of medicine that incorporates study of liver, gallbladder, biliary tree and pancreas as well as management of their disorders.

New framework established for defining prebiotics

The concept of prebiotics – defined as substrates that are selectively utilized by host microorganisms conferring a health benefit – was introduced in the scientific community nearly 30 years ago.

4 Oct 2024

Understanding the role of TIPS in improving renal function amid cirrhosis

Cirrhosis is one of the leading causes of mortality from non-communicable diseases, with complications arising as liver function deteriorates.

26 Sep 2024

New pipeline of drug candidates offers hope for effective MASLD treatments

Non-alcoholic fatty liver disease (NAFLD), recently reclassified as metabolic dysfunction-associated steatotic liver disease (MASLD), has become the most prevalent chronic liver disease globally.

25 Sep 2024

Speech analysis phone app could identify early signs of hepatic encephalopathy

Research from the University of Michigan suggests that one day a phone app could be able to detect the development of hepatic encephalopathy in patients just by listening to them speak.

18 Sep 2024

Review highlights mitochondrial dysfunction in cholestatic liver injury

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the digestion and absorption of fats.

16 Sep 2024

Higher soft drink consumption linked to increased risk of liver disease

Study found that higher soft drink consumption is associated with an increased risk of nonalcoholic fatty liver disease, especially in males, within a cohort of Mexican adults.

16 Sep 2024

Study reveals key role of A20 protein in controlling inflammation in liver disease

Many individuals worldwide suffer from chronic liver disease (CLD), which poses significant concerns for its tendency to lead to hepatocellular carcinoma or liver failure. CLD is characterized by inflammation and fibrosis.

29 Aug 2024

Scientists discover key to activating natural killer cells against cancer

Scientists are on the verge of a cancer breakthrough after working out how the body's immune system targets cells devastated by the disease.

28 Aug 2024

Gut microbiota plays a critical role in rotavirus vaccine efficacy

Certain types of gut bacteria can hinder the efficacy of the rotavirus vaccine, according to researchers at the Institute for Biomedical Sciences at Georgia State University.

27 Aug 2024

Should extremely preterm infants be given probiotics?

Researchers found that probiotics similarly impact the gut microbiome in extremely preterm infants as in very preterm infants, suggesting potential benefits for NEC prevention, but further research is needed.

26 Aug 2024

UC Davis researchers unveil pathway for Salmonella's gut invasion

How do bad bacteria find entry points in the body to cause infection? This question is fundamental for infectious disease experts and people who study bacteria.

20 Aug 2024

Study reveals new insights into urea cycle's role in fatty liver disease

An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States.

16 Aug 2024

Liver stiffness becomes crucial indicator for post-treatment hepatitis C risk assessment

Hepatitis C can be cured in almost all cases with modern medication. However, if advanced liver damage is already present at the time of cure, there is still a residual risk of liver cancer and complications of portal hypertension, such as abdominal fluid, bleeding from the digestive tract and confusion.

14 Aug 2024

IU research sheds light on urea cycle defects and fatty liver disease

An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States.

13 Aug 2024

Mini intestines uncover mechanisms behind COVID-19-related diarrhea and potential treatments

Working with human stem cells that form a kind of "mini intestine-in-a-dish," Johns Hopkins Medicine scientists say they have found several molecular mechanisms for COVID-19-related diarrhea, suggesting potential ways to control it.

6 Aug 2024

New study helps better understand the pathology of fatty liver disease MASH

A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis.

24 Jul 2024

Study identifies trends in the use of glucagon-like peptide-1 receptor agonists

Investigators at Cedars-Sinai and other institutions conducted a nationwide, population-based study to identify trends in the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs)-;prescription medications sold under popular drug names like Ozempic and Wegovy-;in the United States.

22 Jul 2024