High Density Lipoproteins News and Research

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Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

Houston Methodist scientists reversed infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein, showing further evidence that links high cholesterol to female infertility.

15 Mar 2023

How does the gut microbiome affect muscle strength?

Researchers use fecal microbiome transplantation in mouse models to examine the role of gut microbiota in determining muscle strength.

14 Mar 2023

The association of lipid levels with the risk of COVID-19 infection, hospitalization, disease severity, and mortality

A recent study conducted by a team of international scientists has highlighted that individuals with high serum levels of high-density lipoprotein-cholesterol are less susceptible to SARS-CoV-2 infection.

6 Apr 2022

The impact of SARS-CoV-2 on lipids

SARS-CoV-2 appears to alter host lipid biosynthesis by relying on certain human metabolic pathways to survive and multiply effectively.

20 Feb 2022

Sphingolipid profile could predict severity of heart disease in African American patients with lupus

A team of researchers at the Medical University of South Carolina report in Frontiers in Immunology that they have identified a type of fat known as a sphingolipid that could predict the severity of heart disease in African American patients with lupus.

16 Aug 2021

HDL nanoparticles prevent cholesterol movement at membrane receptor to inhibit entry of SARS-CoV-2 pseudovirus in cell culture

As researchers strive to find safe therapeutics for COVID 19, a study suggests that preventing the movement of cholesterol may inhibit viral entry by up to 80%.

17 Dec 2020

Researchers explore molecular factors that drive the severity of COVID-19

While most COVID-19 cases are asymptomatic or mild, severe complications associated with acute respiratory distress have led to more than one million deaths worldwide in just several months.

13 Oct 2020

Study uncovers how the body synthesizes triglycerides

Doctors regularly warn their patients that having high levels of triglycerides, a major dietary fat, can increase the risk of heart disease, diabetes, obesity and fatty liver disease.

13 May 2020

Sphingolipids associated with heart disease in African Americans with lupus

When it comes to cholesterol, we've come to accept a simple narrative. Our risk of heart disease is lower when we have more "good cholesterol," or high-density lipoproteins (HDL), and less "bad cholesterol," or low-density lipoproteins (LDL) and triglycerides.

21 Nov 2019

Parental depression may increase kids' risk for later physical health problems

When parents suffer from depression, kids may be at risk for physical health problems in young adulthood, according to a study from researchers including the University of Georgia's Katherine Ehrlich.

25 Oct 2019

Mystery underlying cardiac toxicity caused by diabetes drugs solved

Like catching two fish with one worm, treating two problems with a single drug is efficient, but exceedingly difficult.

25 Sep 2019

Diet enriched with cottonseed oil improves cholesterol profiles

Researchers at the University of Georgia have found that a high-fat diet enriched with cottonseed oil drastically improved cholesterol profiles in young adult men.

31 Oct 2018

Researchers explore why heart failure and kidney disease correlate

People with chronic kidney disease are at unusually high risk of also developing cardiovascular disease; in fact, a patient with non-dialysis kidney disease is more likely to die of heart failure than to develop end-stage kidney failure.

24 Jul 2018

Study: Postmenopausal factors may impact heart-protective qualities of 'good cholesterol'

Postmenopausal factors may have an impact on the heart-protective qualities of high-density lipoproteins - also known as 'good cholesterol' - according to a study led by researchers in the University of Pittsburgh Graduate School of Public Health.

19 Jul 2018

High-fat, high-cholesterol diet depletes ranks of artery-protecting immune cells

New research from scientists at the La Jolla Institute for Allergy and Immunology shows how a diet high in fat and cholesterol depletes the ranks of artery-protecting immune cells, turning them into promoters of inflammation, which exacerbate atherosclerotic plaque buildup that occurs in cardiovascular disease.

21 Mar 2018

Reduced risk of heart disease for mothers who breastfeed

According to a new study, women who breastfeed their babies for a minimum of 6 months after giving birth have a reduced risk of heart disease in later life.

1 Mar 2018

Study could help doctors to better predict development of cardiovascular disease at earlier stage

Screening methods for cardiovascular diseases such as heart attacks and strokes could be improved by measuring different biological signposts to those currently being tested, a new study led by researchers from King's College London suggests.

21 Feb 2017

Nanodiscs deliver customized therapeutic vaccine for treatment of colon, melanoma cancers

Researchers at the University of Michigan have had initial success in mice using nanodiscs to deliver a customized therapeutic vaccine for the treatment of colon and melanoma cancer tumors.

27 Dec 2016

FCVB 2014 to feature cutting edge research in basic cardiovascular science

Cutting edge research in basic cardiovascular science will be presented at Frontiers in CardioVascular Biology (FCVB) 2014, held 4-6 July at the Palau de Congressos de Catalunya in Barcelona, Spain.

5 Jun 2014

Cholesterol plays vital role in cell mobility and tissue invasion

University of Barcelona's researchers led by Professor Carles Enrich, from the Department of Cell Biology, Immunology and Neurosciences of the Faculty of Medicine at the University of Barcelona and CELLEX Biomedical Research Centre of IDIBAPS, have found that cholesterol plays a key role in cell mobility and tissue invasion.

21 May 2014