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New insights into why people suffer from nickel allergy

The cause of the allergic reaction are T lymphocytes (T cells). These cells are part of the body's defences and normally react to viruses or bacteria in the skin.

31 Aug 2020

GlobalData: NGS technology most likely to provide relief for global backlog of COVID-19 testing

Illumina receiving emergency use authorization from the Food and Drug Administration for diagnosing COVID-19 using its next generation sequencing technology could not have come at a more critical period during this pandemic.

23 Jun 2020

Characterizing "re-positives" in recovered COVID-19 patients

The novel coronavirus pandemic has been spreading silently or explosively in almost every country of the world, causing almost half a million deaths and nearly 8.5 million reported cases in just six months. While much is known about the virus and the illness by now, far more remains unclear. One such is the prevalence and persistence of antiviral immunity following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

19 Jun 2020

Does COVID-19 infect peripheral blood cells?

The emergence of the novel coronavirus outbreak in December 2019 was followed by its spread on a global scale unparalleled in the last 100 years. At present, it has claimed over 322,000 lives the world over, with over 4.88 million cases having tested positive.

19 May 2020

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which constitute clusters of different endocrine cell types.

12 May 2020

DNA damage and inaccurate repair mechanisms jointly cause mutational signatures

Researchers at EMBL's European Bioinformatics Institute, the University of Dundee and the Wellcome Sanger Institute analysed over 2700 genomes from C. elegans worms in order to better understand the causes of mutations.

2 May 2020

Russian researchers explain why new pathogenic viruses are so hard to detect

In a recently published fundamental review dedicated to the diagnostics of viral infections, a Russian research team featuring MIPT researchers was the first to systematically describe and summarize the cutting-edge technologies in the rapidly developing field of genetics.

25 Mar 2020

New biomarkers for diagnosis and prognosis of lung cancer identified

Applying bioinformatics to resolve biological problems. This is the objective of the research group of the University of Malaga "BI4NEXT", which, in one of its latest studies, developed in the Supercomputing and Bioinnovation Center based on biobank samples, has identified new biomarkers for the diagnosis, prognosis and even treatment of lung cancer.

20 Feb 2020

Developing new approaches to fight against multi-resistant pathogens

Developing fundamentally new approaches against multi-resistant germs: This is the goal of the new Bavarian research network bayresq.net which started in January 2020.

9 Feb 2020

Experimental vaccine prevents infection of lung and nasal cavity

Researchers have found that viruses causing human respiratory infections called human metapneumovirus (HMPV) have a special ability to hide itself from the body’s immune system. This prevents the body from fighting the infection off. This very strategy has been used in development of a vaccine against HMPV say the researchers.

3 Feb 2020

Sperm microbiome revealed with RNA sequencing

A new study reports the first-ever detailed description of the human sperm microbiome, using newer RNA sequencing techniques that are capable of discriminating between sperm RNA and that of bacterial contamination or colonization.

2 Feb 2020

Study uncovers large, giant viruses that belong to NCLDV supergroup

While the microbes in a single drop of water could outnumber a small city's population, the number of viruses in the same drop-;the vast majority not harmful to humans could be even larger.

24 Jan 2020

Study shows how sewage plants can remove pharmaceuticals from wastewater

Corals depend on their symbiotic relationships with the algae that they host. But how do they keep algal population growth in check?

9 Jan 2020

Researchers discover hundreds of novel viruses in insects

New viruses which cause diseases often come from animals. Well-known examples of this are the Zika virus transmitted by mosquitoes, bird flu viruses, as well as the MERS virus which is associated with camels. In order to identify new viral diseases quickly and prevent possible epidemics, DZIF scientists at Charité - Universitätsmedizin Berlin are targeting their search at viruses in animals.

8 Jan 2020

Researchers to use human bone remains for studying predictable, postmortem microbes

It's one of the most salient questions in any death investigation, and one of the first asked by both law enforcement and loved ones: Not just how, but when did a person die?

9 Dec 2019

GW-led consortium receives $2.2 million from FDA for Biocompute Object Specification Project

A consortium led by the George Washington University (GW) has been refunded for their BioCompute Object Specification Project, thanks to a $2.2 million, five-year grant from the U.S. Food and Drug Administration.

4 Dec 2019

SEPATH: New template to detect oncogenic viruses and bacteria in human DNA

A new study from the University of East Anglia describes a novel approach to detecting bacteria and viruses that may possibly be causing cancer. Many such associations have already been found, such as HPV (human papilloma virus) infection in cervical cancer, and Helicobacter pylori (H. pylori) in stomach cancer.

22 Oct 2019

Patterns unique to the striatum observed in people with Huntington's disease

The part of the brain that selectively degenerates in people with Huntington's disease (HD), called the striatum, is almost entirely destroyed in the late stages of the disease. Brain samples from mutant HD gene positive individuals who had not yet developed symptoms by time of death are extremely rare. As a consequence, very little is known about the active disease process that causes the devastating symptoms of HD.

21 Oct 2019

DNA metabarcoding could improve analysis of human diet

A study has shown that DNA metabarcoding serves as a powerful new tool for monitoring humans’ intake of plants.

8 Oct 2019

Scientists point to enterovirus infection as cause for acute flaccid myelitis

Scientists at the Center for Infection and Immunity at Columbia University Mailman School of Public Health, the U.S. Centers for Disease Control and Prevention, and the University of California San Diego report antibody evidence in cerebrospinal fluid that points to enterovirus infection as a cause for acute flaccid myelitis, a disease responsible for partially paralyzing more than 560 children in the United States since 2014. Results of the study appear in the journal mBio.

13 Aug 2019