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Researchers discover natural gene therapy for intractable skin disease

Pathogenic gene mutations causing a type of intractable skin disease can be eliminated from some parts of patients' skin as they age, according to Hokkaido University researchers and their collaborators in Japan. This represents a form of natural gene therapy.

1 Apr 2019

Researchers discover 'taste bud cells' in mice lungs after severe bout of flu

Most people who weather an infection with influenza fully recover after a week or two. But for some, a severe case of the flu can actually reshape the architecture of their lungs and forever compromise their respiratory function.

29 Mar 2019

Machine learning approach sheds light on the biology of liver and kidneys after toxin exposure

Exposure to potentially harmful chemicals is a reality of life. Our ancestors, faced with naturally occurring toxins, evolved mechanisms to detoxify and expel damaging substances.

15 Mar 2019

Tactile and proprioceptive stimulation improves effects of perinatal brain injuries in mice

A research conducted by the INc-UAB shows that the same perinatal brain injury caused by hypoxia and ischemia have differentiated effects on each gender, but can be improved through tactile and proprioceptive stimuli.

5 Mar 2019

Groundbreaking AI technology could predict melanoma metastasis

An interdisciplinary team of researchers at Ben-Gurion University of the Negev in Israel and the University of Texas Southwestern Medical Center in Dallas have developed groundbreaking technology to identify melanoma cells that are likely to metastasize to other parts of the body using artificial intelligence.

26 Feb 2019

New breakthrough study can impact drug development and personalized medicine

A breakthrough for brain tumor drug development and personalized medicine published today in Nature Scientific Reports.

6 Feb 2019

In vitro grafts improve blood flow in the hearts of infarcted rats

Advances in stem cell research offer hope for treatments that could help patients regrow heart muscle tissue after heart attacks, a key to achieving more complete recovery.

5 Feb 2019

Leica Microsystems' new THUNDER imagers set to transform visualization of 3D samples

World-leading designer and manufacturer of innovative microscope solutions, Leica Microsystems, has announced the launch of a new class of instruments for high-speed, high-quality imaging of a large diversity of samples, including thick specimens.

From Leica Microsystems GmbH 28 Jan 2019

First probabilistic atlas of thalamus nuclei to better understand the brain

A multidisciplinary study led by BCBL, a Basque research center, opens the door to the investigation of the structure and functions of human thalamic nuclei and their involvement in Alzheimer's, dyslexia, epilepsy, Huntington's and schizophrenia.

20 Nov 2018

Molecular DNA analysis could facilitate more accurate prognosis, treatment of aggressive brain tumors

Meningiomas, a type of brain tumor, are usually easy to treat. However, there are a few subtypes that follow a very aggressive course and have high recurrence rates, i.e. there is a high risk of them coming back after treatment.

19 Nov 2018

FDA authorizes two devices that provide real-time location of parathyroid tissue during surgery

Today, the U.S. Food and Drug Administration permitted marketing of two devices that provide real-time location of parathyroid tissue during surgical procedures such as thyroidectomy (surgery to remove all or part of the thyroid) and parathyroidectomy (surgery to remove one or more parathyroid glands).

2 Nov 2018

Drugs approved for breast cancer treatment are effective and well tolerated in men

There is growing evidence that drugs approved for the treatment of breast cancer in women are also effective and well tolerated in men, according to the largest real-life study yet to investigate treatment and outcomes in men with breast cancer and two further studies to be reported at ESMO 2018.

23 Oct 2018

FOTIVDA expected to be included in new ESMO guidelines for advanced renal cell carcinoma

EUSA Pharma welcomes the news that FOTIVDA (tivozanib) is expected to be included in the upcoming European Society of Medical Oncology clinical practice guidelines for advanced renal cell carcinoma, anticipated to be published at the end of this year.

22 Oct 2018

CDx Diagnostics announces WATS3D data demonstrating crypt dysplasia as risk factor for esophageal cancer

CDx Diagnostics, an innovator in computer synthesized, three dimensional tissue analysis for the early detection and surveillance of Barrett’s esophagus, today announced new data for WATS3D, or Wide Area Transepithelial Sampling with 3D Tissue Analysis, demonstrating the clinical significance of crypt dysplasia as an important risk factor for progression to high-grade esophageal dysplasia or esophageal cancer.

9 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Study reveals molecular mechanisms underlying expansive arterial remodeling

Expansive arterial remodeling comprises a genetically programmed biological response designed to restore homeostatic levels of arterial wall stress after an increase in vessel flow load occurs.

25 Aug 2018

New biosensor tracks oxygen levels in real time in 'organ-on-a-chip' systems

A new biosensor allows researchers to track oxygen levels in real time in "organ-on-a-chip" systems, making it possible to ensure that such systems more closely mimic the function of real organs.

21 Aug 2018

RNA and DNA sequencing platform matches broader swath of drugs to late-stage cancer patients

A comprehensive RNA and DNA sequencing platform benefits late-stage and drug-resistant multiple myeloma patients by determining which drugs would work best for them, according to results from a clinical trial published in JCO Precision Oncology in August.

9 Aug 2018

Scientists create predictive model for neuroblastoma that incorporates early developmental signals

Neuroblastoma, a rare childhood cancer of the sympathetic nervous system, is particularly deadly because it is difficult to detect and thus generally advanced before treatment begins.

9 Jul 2018

AI could improve clinical diagnosis and treatment of prostate cancer

Researchers in Sweden have shown how data-driven AI could contribute to a better understanding of how prostate cancer develops, and even improve clinical diagnosis and treatment of the disease.

26 Jun 2018