Histology News and Research

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New strategy to grow and measure how tumor organoids respond to therapy

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a new method to bioprint miniature tumor organoids that are designed to mimic the function and architecture of real tumors. The improved process allows researchers to use an advanced imaging method to study and analyze individual organoids in great detail, which can help researchers identify personalized treatments for people with rare or hard-to-treat cancers.

7 Jun 2023

Ultraflexible nanoelectrodes improve the efficacy of brain stimulation

Conventional implantable medical devices designed for brain stimulation are often too rigid and bulky for what is one of the body's softest and most delicate tissues.

30 May 2023

Transforming antibiotic resistance testing: a novel, rapid and affordable technique

News Medical speaks with Dr. Sandor Kasas, a lead researcher at Ecole Polytechnique Fédérale de Lausanne in Switzerland.

19 May 2023

Long-term ketogenic diet boosts survival rates in advanced cancer patients

Long-term ketogenic diet shows improved survival rates in cancer patients, with a significantly better overall survival for those following the diet for ≥12 months. Promising results for cancer therapy.

18 May 2023

Study establishes a mechanistic link between obesity and oral cancer immune escape

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the immune system.

16 May 2023

The interaction between white adipose tissue mitochondria and gut microbiota in obesity

Researchers explored the interaction of white adipose tissue mitochondria with gut microbiota in obesity.

4 Apr 2023

Vedolizumab found to be effective for the treatment of chronic pouchitis after colectomy

12% of people with ulcerative colitis need surgery to have their colon removed (colectomy). Most of those have an ileo-anal pouch surgically constructed from their small bowel, which means that they don't have to live with a stoma bag.

31 Mar 2023

Advancements in understanding and treating breast cancer

Researchers describe recent advancements in breast cancer research.

26 Mar 2023

AI-based diagnostic screening system could streamline the diagnosis and treatment of gliomas

Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds -; and possibly streamline the diagnosis and treatment of gliomas, a study suggests.

23 Mar 2023

Study provides strong support for AAV.NT-3 gene therapy in the management of sarcopenia

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "AAV1.NT-3 gene therapy prevents age-related sarcopenia."

16 Mar 2023

UB researchers develop new tool to assess the presence and severity of sarcopenia

Sarcopenia is a degenerative disease characterized by a pathological decrease in muscle strength that particularly affects older people.

13 Mar 2023

What is the effect of low Anti-Müllerian hormone on semen quality?

A recent BMC Medicine study investigated the relationship between Vitamin D and serum Anti-Müllerian hormone (AMH) in infertile men. This study was based on secondary analysis of a randomized clinical trial, which assessed the effect of high-dose Vitamin D plus calcium and placebo on semen quality in Vitamin D deficient infertile men.

10 Mar 2023

Jamaican fruit bat's response to SARS-CoV-2 adapted to human

In a recent study posted to the bioRxiv* server, researchers examined the vulnerability of Jamaican fruit bats (Artibeus jamaicensis) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Feb 2023

Pulmonary morphopathology in COVID-19 caused by the B.1.617.2 Delta variant

Researchers examined the histopathological condition of the lungs of patients who died from COVID-19 caused by the SARS-CoV-2 Delta (B.1.617.2) variant.

3 Feb 2023

Researchers create large-scale 2D and 3D spatial maps of colorectal cancer

In the United States, turning 45 brings with it a rather unpleasant rite of passage: the beginning of regular colonoscopies, in which an endoscope equipped with a light and a camera is used to visually check the colon for signs of cancer.

19 Jan 2023

Advanced MRI tool can reveal new structural insights into atherothrombosis

Atherosclerosis is a long-term arterial vessel wall disease characterized by the build- up of lipid- rich and inflamed plaques.

3 Jan 2023

New ASTRO guideline provides recommendations on the use of radiation therapy for endometrial cancer

A newly updated clinical guideline from the American Society for Radiation Oncology provides recommendations on the use of radiation therapy and systemic therapy after surgery to treat patients with endometrial cancer.

7 Dec 2022

The effect of ubiquitination on SARS-CoV-2 infection and patient prognosis

A recent Clinical and Translational Medicine study utilized several published public datasets to evaluate the biological characteristics associated with the ubiquitination of patients infected with SARS-CoV-2.

2 Dec 2022

Powerful imaging tool creates 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions

Gross anatomy reveals three-dimensional shapes of pathology at a large scale. Histology, in contrast, reveals the microscopic anatomy of biological structures. But that magnification comes at a cost -; histology shows only two-dimensional shapes because it studies small, flat slices of stained tissue.

29 Nov 2022

Photon-counting CT may help to effectively identify post-COVID patients at risk for lung damage

New CT technology outperforms conventional CT in detecting subtle damage in the lungs of patients with persistent symptoms of COVID-19, according to a new study published in Radiology, a journal of the Radiological Society of North America.