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Screening mammography in elderly patients beneficial

Although guidelines keep changing regarding screening mammography in elderly patients, those older than 70 years old continue to benefit from this exam, showing that with frequent mammograms breast cancers can be found sooner, according to a recent study conducted by researchers at Jacobi Medical Center and Albert Einstein College of Medicine, in Bronx, NY.

11 Apr 2008

New hope for children with bilateral Wilms tumors

Physicians at St. Jude Children's Research Hospital have demonstrated that children with bilateral Wilms tumor, a cancer of the kidneys, can retain normal function in both kidneys by undergoing a procedure called bilateral nephron-sparing surgery, even when preoperative scans suggest that the tumors are inoperable.

25 Mar 2008

Two new studies examine non-invasive ways to determine liver fibrosis and cirrhosis

An enhanced version of the Original European Liver Fibrosis panel was found to have good diagnostic accuracy for fibrosis in patients with non-alcoholic fatty liver disease. Conversely, transient elastography was unreliable for detecting cirrhosis in patients with acute liver damage. The studies are published in the February issue of Hepatology, a journal by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The articles are also available online at Wiley Interscience.

5 Feb 2008

Wyeth receives European approval for TORISEL

Wyeth Pharmaceuticals, a division of Wyeth, has announced that the European Commission has approved TORISEL (temsirolimus) for the first-line treatment of patients with advanced renal cell carcinoma (RCC) who have at least three of six prognostic risk factors. TORISEL is the only approved cancer therapy that specifically inhibits the mTOR (mammalian target of rapamycin) kinase, an important regulator of cell proliferation, cell growth and cell survival.

27 Nov 2007

Colorectal cancer screening improves survival in seniors

As people get older, their risk of developing polyps and colorectal cancer increases. Currently, there is no clear evidence or established guideline for the upper age limit for colorectal cancer screening by colonoscopy.

16 Oct 2007

Avastin approved in Europe for advanced lung cancer

Avastin (bevacizumab), Roche's innovative anti-cancer drug, was approved today in Europe for the first-line treatment of patients with advanced non-small cell lung cancer (NSCLC), in combination with platinum-based chemotherapy.

26 Aug 2007

Drug topotecan shows promise against Wilms tumor

St. Jude researchers have shown that the drug topotecan holds promise as a treatment for the recurrent form of a kidney cancer called Wilms tumor, a solid tumor of the kidney that arises from immature kidney cells, and the fifth most common tumor among children.

17 Aug 2007

3-D microscopic views of tiny mouse brains available online

A multi-institutional consortium including Duke University has created startlingly crisp 3-D microscopic views of tiny mouse brains - unveiled layer by layer - by extending the capabilities of conventional magnetic resonance imaging.

10 Jul 2007

Researchers identify the cancer stem cell for rhabdomyosarcoma

As published in the June 1 issue of Genes & Development, Dr. Leonard Zon (Children's Hospital Boston) and colleagues have identified the cancer stem cell for rhabdomyosarcoma, the most common soft-tissue sarcoma of childhood.

17 May 2007

Long-term survival probability in men with clinically localized prostate cancer

Randomized studies comparing conservative therapy to definitive therapy in men with prostate cancer (CaP) are underway, but not yet available.

20 Apr 2007

Patient age remains a controversial factor in predicting prognosis for patients with renal cell carcinoma

In this large population study led by Verhoest and colleagues from several European hospitals, the clinical parameters for four patient age groups were evaluated to determine the influence of age at diagnosis on tumor characteristics and outcomes for RCC.

18 Apr 2007

Testosterone replacement therapy appears to be safe - has little effect on the prostate gland

Preliminary research suggests that testosterone replacement therapy for men with low testosterone levels appears to have little effect on the prostate gland, contrary to some reports that this therapy may be harmful, according to a study in the November 15 issue of JAMA: The Journal of the American Medical Association.

14 Nov 2006

Bladder urothelium in PBS/IC shows distinct differences in keratin profiles

Research groups from the Netherlands and Denmark led by Pilar Laguna studied urothelial involvement in PBS/IC by characterizing the keratin phenotype of bladder urothelium in 18 patients with the disorder.

20 Aug 2006

Computer-aided detection essential in preventing breast cancer

Computer-aided detection improves breast cancers in both screening and diagnostic patients according to a recent study done by a private practice radiologist in Santa Barbara, CA.

2 Aug 2006

Comparative study of ileocecal vs. ileal neobladders in radical cystectomy patients

The use of orthotopic urinary diversion has gained increasing popularity in the past 20 years.

14 Jun 2006

Comparative study of ileocecal vs. ileal neobladders in radical cystectomy patients

The use of orthotopic urinary diversion has gained increasing popularity in the past 20 years.

18 May 2006

Renal cell carcinoma in the pediatric population

While the incidence of renal cell carcinoma (RCC) is rising, it remains a relatively uncommon malignancy in the pediatric population, where it represents only 2-6% of solid renal malignancies.

16 May 2006

MicroCT-based virtual histology

Utah and Texas researchers combined miniature medical CT scans with high-tech computer methods to produce detailed three-dimensional images of mouse embryos - an efficient new method to test the safety of medicines and learn how mutant genes cause birth defects or cancer.

8 May 2006

Selecting patients for breast conserving therapy: The importance of lobular histology

Invasive lobular carcinoma (ILC) of the breast can be treated with breast conserving surgery (BCT), as is invasive ductal carcinoma (IDC), without greater future risk of radical surgical treatment or additional surgeries, according to a new study.

8 May 2006

Significant changes in tumor growth can be detected through short interval follow-up

These growths may have important clinical implications in the management of patients, enabling early discontinuation of potentially toxic chemotherapy drugs.

4 May 2006